Click here to switch to the map view.

The map label for this gene is paaE [H]

Identifier: 169628009

GI number: 169628009

Start: 901790

End: 902890

Strand: Direct

Name: paaE [H]

Synonym: MAB_0910

Alternate gene names: 169628009

Gene position: 901790-902890 (Clockwise)

Preceding gene: 169628008

Following gene: 169628010

Centisome position: 17.8

GC content: 64.67

Gene sequence:

>1101_bases
ATGACCACCGAATTGTCCGCGCCCACCACCGGACGCGGCATGCGCAACCGGCCGTTCCGCACGGTGCGGGTCGCCGAGGT
ACAGCAGCTGTGCGCCGATGCTGCGGCTATCACTTTCGCGGTGCCCGACCAGTACATCGACGAATTCGGTTTCGCCCCTG
GGCAATCCATCACAGTGCGCCGGAACGTCGACGGAGTCGAGCAGCGCCGCACCTATTCGATCTGCTCGCCGCTCGGGGCC
CGACCCCGCATCGGGGTCCGCGAGGTGCCCGGGGGAGCGTGCTCAGGGTGGCTGGTGCACCAGCTGTCGGCCGGCGATGA
GATCGAGGTCCAGCCGCCGTCCGGGAACTTCGTTGCCGATGCCACGACGCCGGCACATCACGTTCTGATCGCCGCCGGAT
CGGGTATCACGCCCCTGCTGTCCATCGCCGCATCGGTTTTGGCGCAGCCGGATTCGCGGGTCACCCTGCTCTACGGAAAT
CGGCGGGCCAACACCGTCATGTTCGCCGACGAGCTTGCCGACCTGAAAGACACGTACCACAGCCGACTGCAACTGGTCCA
CGTACTTTCACGGGAACCGCGTACCGTCGAGCTGTTCAGTGGGCGACTCGATCACCAGCGGATCCGCGTGCTCCTGCAGC
AGCTGGTGCCGATAGCTGCCGTCGACCATGTGTGGTTGTGTGGGCCGTTTGGCATGGTCACCGATGCCCAAGCGGCGCTG
CGGGAGCTCGGGGTGGAAGACAGCCGCATTCACCAAGAGTTGTTCTTCGTCGAAGACGCCGCCCCACCTCAGGCAGAGCA
TCGAGACGGAGTTGCGTCAGGACCGGTCAGTGAAGTGACCATTGTCTTGGACGGGGCGACCAGCACCATGGCATTGCCGC
GCAACGTGTCAGTCCTCGACGCGGCCCAACGATCGCGCGACGATCTGCCATTCGCCTGTAAGGGCGGTGTGTGTGGCACC
TGTCGCGCGAAGGTCACCGGGGGTGCGGTCGACATGCGCCGCAATTATGCCCTTGAGCCGGACGAGATAGACGCCGGATT
TGTGCTGACCTGTCAGTCCTATCCGACCACCGATTCATTGACCGTCGACTTCGACGCCTGA

Upstream 100 bases:

>100_bases
GAAACCGAAATGACGTCCGAATTCGGTTCGACCGCCTGCAAATCGCTGCACAGATGCATCCACTGCGGCGAACCATTCGA
CCGAATCAAGGAACTCTGAC

Downstream 100 bases:

>100_bases
AATCCCACCTCACCCACCGGAGTACGCCATGATCGAAACCGTCGAACGCAGCGAGAGCCACAGCGTGGCGTGCTCGCCTG
ATGAGCTCGAGCCCATCGAA

Product: putative phenylacetic acid degradation protein PaaE/phenylacetate-CoA oxygenase/reductase, PaaK subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTTELSAPTTGRGMRNRPFRTVRVAEVQQLCADAAAITFAVPDQYIDEFGFAPGQSITVRRNVDGVEQRRTYSICSPLGA
RPRIGVREVPGGACSGWLVHQLSAGDEIEVQPPSGNFVADATTPAHHVLIAAGSGITPLLSIAASVLAQPDSRVTLLYGN
RRANTVMFADELADLKDTYHSRLQLVHVLSREPRTVELFSGRLDHQRIRVLLQQLVPIAAVDHVWLCGPFGMVTDAQAAL
RELGVEDSRIHQELFFVEDAAPPQAEHRDGVASGPVSEVTIVLDGATSTMALPRNVSVLDAAQRSRDDLPFACKGGVCGT
CRAKVTGGAVDMRRNYALEPDEIDAGFVLTCQSYPTTDSLTVDFDA

Sequences:

>Translated_366_residues
MTTELSAPTTGRGMRNRPFRTVRVAEVQQLCADAAAITFAVPDQYIDEFGFAPGQSITVRRNVDGVEQRRTYSICSPLGA
RPRIGVREVPGGACSGWLVHQLSAGDEIEVQPPSGNFVADATTPAHHVLIAAGSGITPLLSIAASVLAQPDSRVTLLYGN
RRANTVMFADELADLKDTYHSRLQLVHVLSREPRTVELFSGRLDHQRIRVLLQQLVPIAAVDHVWLCGPFGMVTDAQAAL
RELGVEDSRIHQELFFVEDAAPPQAEHRDGVASGPVSEVTIVLDGATSTMALPRNVSVLDAAQRSRDDLPFACKGGVCGT
CRAKVTGGAVDMRRNYALEPDEIDAGFVLTCQSYPTTDSLTVDFDA
>Mature_365_residues
TTELSAPTTGRGMRNRPFRTVRVAEVQQLCADAAAITFAVPDQYIDEFGFAPGQSITVRRNVDGVEQRRTYSICSPLGAR
PRIGVREVPGGACSGWLVHQLSAGDEIEVQPPSGNFVADATTPAHHVLIAAGSGITPLLSIAASVLAQPDSRVTLLYGNR
RANTVMFADELADLKDTYHSRLQLVHVLSREPRTVELFSGRLDHQRIRVLLQQLVPIAAVDHVWLCGPFGMVTDAQAALR
ELGVEDSRIHQELFFVEDAAPPQAEHRDGVASGPVSEVTIVLDGATSTMALPRNVSVLDAAQRSRDDLPFACKGGVCGTC
RAKVTGGAVDMRRNYALEPDEIDAGFVLTCQSYPTTDSLTVDFDA

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=353, Percent_Identity=41.643059490085, Blast_Score=260, Evalue=9e-71,
Organism=Escherichia coli, GI1787098, Length=346, Percent_Identity=26.5895953757225, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788104, Length=323, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788903, Length=215, Percent_Identity=30.2325581395349, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322146, Length=238, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323510, Length=199, Percent_Identity=26.6331658291457, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39458; Mature: 39327

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTELSAPTTGRGMRNRPFRTVRVAEVQQLCADAAAITFAVPDQYIDEFGFAPGQSITVR
CCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHEEEEECCHHHHHHHCCCCCCEEEEE
RNVDGVEQRRTYSICSPLGARPRIGVREVPGGACSGWLVHQLSAGDEIEVQPPSGNFVAD
ECCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCHHHEEECCCCEEEEECCCCCEEEE
ATTPAHHVLIAAGSGITPLLSIAASVLAQPDSRVTLLYGNRRANTVMFADELADLKDTYH
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHH
SRLQLVHVLSREPRTVELFSGRLDHQRIRVLLQQLVPIAAVDHVWLCGPFGMVTDAQAAL
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHH
RELGVEDSRIHQELFFVEDAAPPQAEHRDGVASGPVSEVTIVLDGATSTMALPRNVSVLD
HHHCCCHHHHHHHHEEEECCCCCCCHHCCCCCCCCCCEEEEEEECCCCEEECCCCCHHHH
AAQRSRDDLPFACKGGVCGTCRAKVTGGAVDMRRNYALEPDEIDAGFVLTCQSYPTTDSL
HHHHCCCCCCEEECCCCCCCCEEEECCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCE
TVDFDA
EEEECC
>Mature Secondary Structure 
TTELSAPTTGRGMRNRPFRTVRVAEVQQLCADAAAITFAVPDQYIDEFGFAPGQSITVR
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHEEEEECCHHHHHHHCCCCCCEEEEE
RNVDGVEQRRTYSICSPLGARPRIGVREVPGGACSGWLVHQLSAGDEIEVQPPSGNFVAD
ECCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCHHHEEECCCCEEEEECCCCCEEEE
ATTPAHHVLIAAGSGITPLLSIAASVLAQPDSRVTLLYGNRRANTVMFADELADLKDTYH
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHH
SRLQLVHVLSREPRTVELFSGRLDHQRIRVLLQQLVPIAAVDHVWLCGPFGMVTDAQAAL
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHH
RELGVEDSRIHQELFFVEDAAPPQAEHRDGVASGPVSEVTIVLDGATSTMALPRNVSVLD
HHHCCCHHHHHHHHEEEECCCCCCCHHCCCCCCCCCCEEEEEEECCCCEEECCCCCHHHH
AAQRSRDDLPFACKGGVCGTCRAKVTGGAVDMRRNYALEPDEIDAGFVLTCQSYPTTDSL
HHHHCCCCCCEEECCCCCCCCEEEECCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCE
TVDFDA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]