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The map label for this gene is paaG [H]

Identifier: 169628004

GI number: 169628004

Start: 898130

End: 898933

Strand: Direct

Name: paaG [H]

Synonym: MAB_0905

Alternate gene names: 169628004

Gene position: 898130-898933 (Clockwise)

Preceding gene: 169628003

Following gene: 169628005

Centisome position: 17.72

GC content: 67.54

Gene sequence:

>804_bases
ATGACTCAAACCGCACCGGCCGCCGTCGCGTACTCAGTGAACCACGCTGGCGTCGCTGCGATCGTGCTCGATCGGCCGGA
GGCGTCGAACGCGCTTGACCGGACGATGAAAACCGAACTGCTGCAGGCTTTGTTGGCAGCGGGCGGTGATCCAGCGGTAC
GCGCGGTCGTCATGAGCGCAGCCGGTAAGAACTTCTGCGTCGGCCAGGATCTTGCCGAGCATGTCGAGGCGCTGCGCGAC
GACCCGGCTCACGCGATGGACACCGTGCGCGAGCACTACAACCCGGTCCTGGAGGCGTTGGATGCCATCAAGGTGCCGGT
CGTCGTGGCGATCAACGGCGCCTGTGTGGGCGCGGGGTTGGGCTTGGCGTTGGGTGCCGATATCCGTATCGCCGGTCAGC
GCGCCAAGTTCGGGACCGCTTTCACCGGCATCGGCCTAGCCGCGGATTCCGCGTTGTCGGCGTCGTTGCCAAGGCTCATC
GGAGCTAGCCGGGCGACGGCCATGTTCCTGCTCGGTGACACCATCGATGCCCCGACGGCCCACACGTGGGGGCTGGTGCA
CGAGGTGGTTGACGAGGGCTCACCCGCCGACGTAGCGAACTCCGTCGCCGGTCGCCTGGCCGGCGGGCCCACCGCCGCCT
TCTCAGAGGTCAAGGAACTGTTGCGTCGCAACGCTGTCGCGCCACTAGGCGATGTCCTAGAACGGGAAGCGAGCGCCCAG
CAGCGCCTCGGGGCGTCCCGCGACCACAGCGCTGCGGTGGAGGCATTCCTGGCCAAGGACAAGCCGGTCTTCGTCGGCCG
CTGA

Upstream 100 bases:

>100_bases
CGAAACTGCTGCGGGCCAAGGTTGCCGAGGGCAACCTTGGCCGCAAGACCGGGCAGGGCTTTTTTCGCTGGTCCAGCTGA
ACATCGTCAGAGGAGGAATC

Downstream 100 bases:

>100_bases
TCGATCGAGACTTGTGCTCCGCGTTCGAATCCGGCACACTCAAATAACCGAACATTCGGTCGGTAATCAGGAGGATTTGA
TGACAGTCACCGATATCTCA

Product: putative enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRD
DPAHAMDTVREHYNPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTAFTGIGLAADSALSASLPRLI
GASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQ
QRLGASRDHSAAVEAFLAKDKPVFVGR

Sequences:

>Translated_267_residues
MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRD
DPAHAMDTVREHYNPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTAFTGIGLAADSALSASLPRLI
GASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQ
QRLGASRDHSAAVEAFLAKDKPVFVGR
>Mature_266_residues
TQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRDD
PAHAMDTVREHYNPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTAFTGIGLAADSALSASLPRLIG
ASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQQ
RLGASRDHSAAVEAFLAKDKPVFVGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4757968, Length=235, Percent_Identity=30.2127659574468, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI49355787, Length=235, Percent_Identity=30.2127659574468, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI25453481, Length=235, Percent_Identity=29.7872340425532, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI51538573, Length=235, Percent_Identity=29.7872340425532, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4757966, Length=235, Percent_Identity=29.7872340425532, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI51538581, Length=235, Percent_Identity=29.7872340425532, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=30.3643724696356, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI221136756, Length=231, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221136753, Length=231, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221307494, Length=231, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI260274832, Length=247, Percent_Identity=25.1012145748988, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI70995211, Length=151, Percent_Identity=31.7880794701987, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45643119, Length=247, Percent_Identity=25.1012145748988, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260275230, Length=247, Percent_Identity=25.1012145748988, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542718, Length=252, Percent_Identity=28.1746031746032, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI116235487, Length=221, Percent_Identity=28.9592760180996, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787660, Length=252, Percent_Identity=37.3015873015873, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787659, Length=251, Percent_Identity=32.2709163346614, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=28.735632183908, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788597, Length=187, Percent_Identity=30.4812834224599, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790281, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082183, Length=253, Percent_Identity=24.5059288537549, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=30.6122448979592, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=198, Percent_Identity=30.8080808080808, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=30.6451612903226, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=198, Percent_Identity=28.7878787878788, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=252, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=246, Percent_Identity=26.4227642276423, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=183, Percent_Identity=30.6010928961749, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=27.5303643724696, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=218, Percent_Identity=28.4403669724771, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=167, Percent_Identity=31.1377245508982, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19920382, Length=258, Percent_Identity=31.7829457364341, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129971, Length=180, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653477, Length=180, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357171, Length=216, Percent_Identity=30.0925925925926, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19922422, Length=190, Percent_Identity=26.8421052631579, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571729, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571730, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650670, Length=224, Percent_Identity=27.2321428571429, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27337; Mature: 27206

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSA
CCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGKNFCVGQDLAEHVEALRDDPAHAMDTVREHYNPVLEALDAIKVPVVVAINGACVGAGL
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCC
GLALGADIRIAGQRAKFGTAFTGIGLAADSALSASLPRLIGASRATAMFLLGDTIDAPTA
HHHCCCCEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCC
HTWGLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQ
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QRLGASRDHSAAVEAFLAKDKPVFVGR
HHCCCCCCHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure 
TQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSA
CCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGKNFCVGQDLAEHVEALRDDPAHAMDTVREHYNPVLEALDAIKVPVVVAINGACVGAGL
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCC
GLALGADIRIAGQRAKFGTAFTGIGLAADSALSASLPRLIGASRATAMFLLGDTIDAPTA
HHHCCCCEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCC
HTWGLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQ
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QRLGASRDHSAAVEAFLAKDKPVFVGR
HHCCCCCCHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]