Click here to switch to the map view.

The map label for this gene is kstR2 [H]

Identifier: 169628000

GI number: 169628000

Start: 894548

End: 895168

Strand: Reverse

Name: kstR2 [H]

Synonym: MAB_0901c

Alternate gene names: 169628000

Gene position: 895168-894548 (Counterclockwise)

Preceding gene: 169628012

Following gene: 169627999

Centisome position: 17.67

GC content: 64.57

Gene sequence:

>621_bases
ATGACCACGCCCCGCACACGCCCGAGCCGACAGGTGGGTCGACCGGGCTACGACCTGGACTCACTCCTGGCGGTGGCGGT
AAGCGTGTTCAATCAGCGCGGCTACGACGGCACCTCAATGGAGCATCTCTCCACACGGCTAGGGATCAGCAAGTCGTCGA
TCTACCACCATGTGAGCGGCAAAGAGGAACTGTTGCGACTCGCGGTCGATCGGGCGCTCGACGCACTGTTCGCCGCGACC
GAGGCCCCCGACACCACCACCGGCCCGGCAATCGATCGCCTGGAAAACCTGGTGAAGCGCAGTATTCAGGTGCTGGTCCA
AGAGTTGCCCTACGTGACGCTGCTGCTACGCATCCGGGGGAACACTGCTGCCGAACGGCGCGCACTGGCCCGCCGCCGAG
AGTTCGATGACATCGTCGGCAACCTGGTCGAGGAAGCCTGCAATGAGGGCAGCATCCGCGCCGGAGTGGATCCCGCATTG
ACGAGCCGACTCATTTTCGGCACCGTCAACTCGCTGATCGAGTGGTATCGACCCAGCCGCACCCTGTCCGCCGACGAGGT
TGCCGACGCGGTCGCCACGATGATTTTCGACGGGCTGCGGACCCGCTCGGGTCAGCACTGA

Upstream 100 bases:

>100_bases
AAAACATTAATAACCGATCGTTCGGTCGGTTGTCTAGAGAGGCCGGGACCGTTGGGAGTGGAAACGCCACCAGCGCACAC
GCGGTGCGATGATTGTCGTC

Downstream 100 bases:

>100_bases
CCGTTCGGTCGGCCACAACACCCCCTGCCAGATCTTGACGCGCACCCGCTCCTGCTGCCAAGGTCATTACCGAACGAATG
GACGGTTGGTAAGGAGTGTG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTTPRTRPSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTSMEHLSTRLGISKSSIYHHVSGKEELLRLAVDRALDALFAAT
EAPDTTTGPAIDRLENLVKRSIQVLVQELPYVTLLLRIRGNTAAERRALARRREFDDIVGNLVEEACNEGSIRAGVDPAL
TSRLIFGTVNSLIEWYRPSRTLSADEVADAVATMIFDGLRTRSGQH

Sequences:

>Translated_206_residues
MTTPRTRPSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTSMEHLSTRLGISKSSIYHHVSGKEELLRLAVDRALDALFAAT
EAPDTTTGPAIDRLENLVKRSIQVLVQELPYVTLLLRIRGNTAAERRALARRREFDDIVGNLVEEACNEGSIRAGVDPAL
TSRLIFGTVNSLIEWYRPSRTLSADEVADAVATMIFDGLRTRSGQH
>Mature_205_residues
TTPRTRPSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTSMEHLSTRLGISKSSIYHHVSGKEELLRLAVDRALDALFAATE
APDTTTGPAIDRLENLVKRSIQVLVQELPYVTLLLRIRGNTAAERRALARRREFDDIVGNLVEEACNEGSIRAGVDPALT
SRLIFGTVNSLIEWYRPSRTLSADEVADAVATMIFDGLRTRSGQH

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22720; Mature: 22589

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPRTRPSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTSMEHLSTRLGISKSSIYHHVSG
CCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCC
KEELLRLAVDRALDALFAATEAPDTTTGPAIDRLENLVKRSIQVLVQELPYVTLLLRIRG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
NTAAERRALARRREFDDIVGNLVEEACNEGSIRAGVDPALTSRLIFGTVNSLIEWYRPSR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TLSADEVADAVATMIFDGLRTRSGQH
CCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTPRTRPSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTSMEHLSTRLGISKSSIYHHVSG
CCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCC
KEELLRLAVDRALDALFAATEAPDTTTGPAIDRLENLVKRSIQVLVQELPYVTLLLRIRG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
NTAAERRALARRREFDDIVGNLVEEACNEGSIRAGVDPALTSRLIFGTVNSLIEWYRPSR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TLSADEVADAVATMIFDGLRTRSGQH
CCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA