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The map label for this gene is moaCB [H]

Identifier: 169627964

GI number: 169627964

Start: 864027

End: 864506

Strand: Direct

Name: moaCB [H]

Synonym: MAB_0865

Alternate gene names: 169627964

Gene position: 864027-864506 (Clockwise)

Preceding gene: 169627963

Following gene: 169627965

Centisome position: 17.05

GC content: 69.79

Gene sequence:

>480_bases
ATGGACCCGACCCTGAGATCGGCGCGGGTGATCGTGGCCTCCACTCGGGCGGCAACCGGTCAGTACACCGATAGGACAGG
CCCCATCATCGTCGAATGGCTTGGTGCACAAGGATTCCGTGTAGACGAGCCGGTTGTGGTGCCCGACGGTGAGGCGGTGG
GAGACGCGATACGTTCCGCGCTCGGCGCCTCACTCGTCATCACCACCGGAGGCACCGGGCTTTCGCCCACCGATTCCACT
CCCGAACAGACCGCCGCGTTGCTGGACTATCAGGTCCCAGGCCTGGCCGATGCGATCCGGCGCTCCGGGCTGCCCGCGGT
CCCCACCAGCATCCTGTCCCGCGGCGTCTGCGGGGTCGCCGGGCGCACCCTGGTGGTCAACCTGCCCGGCTCCGCCGGCG
GCGTCCGCGACGGGCTCGCGGTGCTCGGCGGCGTGCTCGGCCACGCCTTGGACCAGCTAGCCGGGGGTGATCACGTATGA

Upstream 100 bases:

>100_bases
TTGCCGGCCTGACCTTGCACGACATGGTCAAGGCCGTCGATCCCGCCTCACGTATCGACGACGTCAGGGTGCTACGCAAA
GAGGGCGGTAAGACCGGAAC

Downstream 100 bases:

>100_bases
GCACCGCCGTCACTCGTGCCCTGTTGACCGCGGAGTCCATCTCGCTGATCGAACACGAGAGGCTGGTCGATCATGAATCG
GCCGGCGCCACTGTTGGATT

Product: molybdopterin biosynthesis protein Mog

Products: NA

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdenum cofactor biosynthesis protein B [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MDPTLRSARVIVASTRAATGQYTDRTGPIIVEWLGAQGFRVDEPVVVPDGEAVGDAIRSALGASLVITTGGTGLSPTDST
PEQTAALLDYQVPGLADAIRRSGLPAVPTSILSRGVCGVAGRTLVVNLPGSAGGVRDGLAVLGGVLGHALDQLAGGDHV

Sequences:

>Translated_159_residues
MDPTLRSARVIVASTRAATGQYTDRTGPIIVEWLGAQGFRVDEPVVVPDGEAVGDAIRSALGASLVITTGGTGLSPTDST
PEQTAALLDYQVPGLADAIRRSGLPAVPTSILSRGVCGVAGRTLVVNLPGSAGGVRDGLAVLGGVLGHALDQLAGGDHV
>Mature_159_residues
MDPTLRSARVIVASTRAATGQYTDRTGPIIVEWLGAQGFRVDEPVVVPDGEAVGDAIRSALGASLVITTGGTGLSPTDST
PEQTAALLDYQVPGLADAIRRSGLPAVPTSILSRGVCGVAGRTLVVNLPGSAGGVRDGLAVLGGVLGHALDQLAGGDHV

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=90, Percent_Identity=43.3333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI10880983, Length=90, Percent_Identity=43.3333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1786190, Length=133, Percent_Identity=35.3383458646617, Blast_Score=79, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564954, Length=155, Percent_Identity=36.1290322580645, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17136978, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24638841, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR020817
- InterPro:   IPR012247
- InterPro:   IPR008284
- InterPro:   IPR001453
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC; PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 15917; Mature: 15917

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPTLRSARVIVASTRAATGQYTDRTGPIIVEWLGAQGFRVDEPVVVPDGEAVGDAIRSA
CCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCHHHHHHHHHH
LGASLVITTGGTGLSPTDSTPEQTAALLDYQVPGLADAIRRSGLPAVPTSILSRGVCGVA
HCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHCCCCCCC
GRTLVVNLPGSAGGVRDGLAVLGGVLGHALDQLAGGDHV
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDPTLRSARVIVASTRAATGQYTDRTGPIIVEWLGAQGFRVDEPVVVPDGEAVGDAIRSA
CCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCHHHHHHHHHH
LGASLVITTGGTGLSPTDSTPEQTAALLDYQVPGLADAIRRSGLPAVPTSILSRGVCGVA
HCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHCCCCCCC
GRTLVVNLPGSAGGVRDGLAVLGGVLGHALDQLAGGDHV
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9495759 [H]