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The map label for this gene is ybdL [H]

Identifier: 169627946

GI number: 169627946

Start: 841816

End: 842985

Strand: Reverse

Name: ybdL [H]

Synonym: MAB_0847c

Alternate gene names: 169627946

Gene position: 842985-841816 (Counterclockwise)

Preceding gene: 169627947

Following gene: 169627939

Centisome position: 16.64

GC content: 65.64

Gene sequence:

>1170_bases
GTGAATCAGAGAACCGTCGAACGGTTACGTCCTTTCGGCGCAACGATCTTCGCCGAGATGTCGGCACTGGCCGTCCGGCA
TGACGCGATCAATCTTGGTCAGGGCTTCCCCGACGAGGACGGACCCGCATCCATGCTCGATGCGGCGCAACAGGCCATCC
GCTCCGGCCTGAATCAATATCCGCCGGGGCTGGGCATTCCCGAATTACGCCGGGCCATCACCGCCGATCGGCTCGCCCGC
TACGGCGAGGAGCTTGACCCGGACACCCAGGTGCTGGTGACCGTCGGCGCCACCGAAGCGATCGCCGGCGCCCTGCTCGG
CCTCGTCGAACCCGGTTCCGAGGTCATCCTGATCGAGCCCTACTACGACTCCTACGCCGCCGTGGTAGCGATGGCGGGAG
CGGTCCGCGTGCCCGTGCCCCTCGTACCGGACGGGGCGGGCTTCGCATTGGATACCGACGCGCTGGCGGCGGCCATCACG
CCCCGGACGGCGGCGCTGGTGATCAACTCGCCGCATAACCCGACGGGCAAGGTGTTCACCGATACCGAGTTGGCGCGGAT
AGCCGAGCTCGCGGTGGAACACGACCTGCTTGTCGTCTCCGACGAGGTATACGAGCGCCTGCTTTTCGATGGGCGCACCC
AAACTCCGATGGCAAGCCTGCCCGGGATGGCCGACCGGACCGTGACCATCTCCAGCGCCGCCAAGACATTCAACTGCACC
GGTTGGAAAATTGGCTGGGCCTGTGGCACGCCGGAGTTGGTCGCGGGCGTGCGGGCCGCTAAACAGTTCCTCTCCTATGT
CGGCGGCGGACCATTTCAACCGGCGGTGGCAGTGGCCCTGGACACCGAACAGTCGTGGGTGAAGACCCTACGAGAATCAC
TGCAGCGCAGGCGCGATCGCCTCTCGGCCGCCCTCACTGGCCTGGGATTCGAGGTGCACAGCAGTGACGGCGGATACTTT
GTCTGCGCCGATCCGCGGCCGCTCGGGTTCAGCGATAGCGCGGAGCTCTGCCGGCGTTTACCGGAAACTGTTGGCGTCGC
CGCAGTCCCGGTAAGCGCCTTCTGTGACAGATACGCCGACCAATGGAATCACTTGGTGCGGTTCACCTTCGCCAAGCGCG
ATGTGGTGATCGATGAGGCCATCACCCGCCTGGCCCGGCTAGGAGCCTAG

Upstream 100 bases:

>100_bases
CCCGATCCCGGATACCGACCTGTCCTTCGAACCGCCCAGCTGCTAAGTCCAGCGGTAGGCTGCCCGGCATGGAGCCGCGG
CACACCGAACACGGGCCAGC

Downstream 100 bases:

>100_bases
GCCGGTCGCCATCTCACCGGGACGCTGCCGCGCCTTGGCCAGCCCCGGCAGGACCTTGATGAAGTCGGTGATCTCCGCTA
CCGCCCGCCGCGCATCCGGG

Product: aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNQRTVERLRPFGATIFAEMSALAVRHDAINLGQGFPDEDGPASMLDAAQQAIRSGLNQYPPGLGIPELRRAITADRLAR
YGEELDPDTQVLVTVGATEAIAGALLGLVEPGSEVILIEPYYDSYAAVVAMAGAVRVPVPLVPDGAGFALDTDALAAAIT
PRTAALVINSPHNPTGKVFTDTELARIAELAVEHDLLVVSDEVYERLLFDGRTQTPMASLPGMADRTVTISSAAKTFNCT
GWKIGWACGTPELVAGVRAAKQFLSYVGGGPFQPAVAVALDTEQSWVKTLRESLQRRRDRLSAALTGLGFEVHSSDGGYF
VCADPRPLGFSDSAELCRRLPETVGVAAVPVSAFCDRYADQWNHLVRFTFAKRDVVIDEAITRLARLGA

Sequences:

>Translated_389_residues
MNQRTVERLRPFGATIFAEMSALAVRHDAINLGQGFPDEDGPASMLDAAQQAIRSGLNQYPPGLGIPELRRAITADRLAR
YGEELDPDTQVLVTVGATEAIAGALLGLVEPGSEVILIEPYYDSYAAVVAMAGAVRVPVPLVPDGAGFALDTDALAAAIT
PRTAALVINSPHNPTGKVFTDTELARIAELAVEHDLLVVSDEVYERLLFDGRTQTPMASLPGMADRTVTISSAAKTFNCT
GWKIGWACGTPELVAGVRAAKQFLSYVGGGPFQPAVAVALDTEQSWVKTLRESLQRRRDRLSAALTGLGFEVHSSDGGYF
VCADPRPLGFSDSAELCRRLPETVGVAAVPVSAFCDRYADQWNHLVRFTFAKRDVVIDEAITRLARLGA
>Mature_389_residues
MNQRTVERLRPFGATIFAEMSALAVRHDAINLGQGFPDEDGPASMLDAAQQAIRSGLNQYPPGLGIPELRRAITADRLAR
YGEELDPDTQVLVTVGATEAIAGALLGLVEPGSEVILIEPYYDSYAAVVAMAGAVRVPVPLVPDGAGFALDTDALAAAIT
PRTAALVINSPHNPTGKVFTDTELARIAELAVEHDLLVVSDEVYERLLFDGRTQTPMASLPGMADRTVTISSAAKTFNCT
GWKIGWACGTPELVAGVRAAKQFLSYVGGGPFQPAVAVALDTEQSWVKTLRESLQRRRDRLSAALTGLGFEVHSSDGGYF
VCADPRPLGFSDSAELCRRLPETVGVAAVPVSAFCDRYADQWNHLVRFTFAKRDVVIDEAITRLARLGA

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=35, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=35, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI95147551, Length=415, Percent_Identity=34.4578313253012, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI169881279, Length=415, Percent_Identity=34.4578313253012, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI169881281, Length=413, Percent_Identity=29.5399515738499, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI149944424, Length=321, Percent_Identity=25.5451713395639, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4507369, Length=200, Percent_Identity=27, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786816, Length=381, Percent_Identity=36.745406824147, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=30.2631578947368, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1788627, Length=232, Percent_Identity=28.8793103448276, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787710, Length=351, Percent_Identity=28.4900284900285, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787909, Length=254, Percent_Identity=26.7716535433071, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=419, Percent_Identity=36.2768496420048, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI71994476, Length=419, Percent_Identity=36.2768496420048, Blast_Score=237, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17567369, Length=407, Percent_Identity=33.6609336609337, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17567663, Length=337, Percent_Identity=24.3323442136499, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=31.701030927835, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323118, Length=364, Percent_Identity=21.978021978022, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=36.1650485436893, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=36.1650485436893, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=36.1650485436893, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=36.1650485436893, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI18859735, Length=210, Percent_Identity=28.0952380952381, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 41609; Mature: 41609

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRTVERLRPFGATIFAEMSALAVRHDAINLGQGFPDEDGPASMLDAAQQAIRSGLNQY
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PPGLGIPELRRAITADRLARYGEELDPDTQVLVTVGATEAIAGALLGLVEPGSEVILIEP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEC
YYDSYAAVVAMAGAVRVPVPLVPDGAGFALDTDALAAAITPRTAALVINSPHNPTGKVFT
CHHHHHHHHHHHCCCCCCCEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCCEEC
DTELARIAELAVEHDLLVVSDEVYERLLFDGRTQTPMASLPGMADRTVTISSAAKTFNCT
HHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEECCCCEECCC
GWKIGWACGTPELVAGVRAAKQFLSYVGGGPFQPAVAVALDTEQSWVKTLRESLQRRRDR
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
LSAALTGLGFEVHSSDGGYFVCADPRPLGFSDSAELCRRLPETVGVAAVPVSAFCDRYAD
HHHHHHHCCEEEECCCCCEEEECCCCCCCCCCHHHHHHHCHHHHCCHHCCHHHHHHHHHH
QWNHLVRFTFAKRDVVIDEAITRLARLGA
HHHHHEEEEHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQRTVERLRPFGATIFAEMSALAVRHDAINLGQGFPDEDGPASMLDAAQQAIRSGLNQY
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PPGLGIPELRRAITADRLARYGEELDPDTQVLVTVGATEAIAGALLGLVEPGSEVILIEP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEC
YYDSYAAVVAMAGAVRVPVPLVPDGAGFALDTDALAAAITPRTAALVINSPHNPTGKVFT
CHHHHHHHHHHHCCCCCCCEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCCEEC
DTELARIAELAVEHDLLVVSDEVYERLLFDGRTQTPMASLPGMADRTVTISSAAKTFNCT
HHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEECCCCEECCC
GWKIGWACGTPELVAGVRAAKQFLSYVGGGPFQPAVAVALDTEQSWVKTLRESLQRRRDR
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
LSAALTGLGFEVHSSDGGYFVCADPRPLGFSDSAELCRRLPETVGVAAVPVSAFCDRYAD
HHHHHHHCCEEEECCCCCEEEECCCCCCCCCCHHHHHHHCHHHHCCHHCCHHHHHHHHHH
QWNHLVRFTFAKRDVVIDEAITRLARLGA
HHHHHEEEEHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]