Click here to switch to the map view.

The map label for this gene is desA1 [H]

Identifier: 169627855

GI number: 169627855

Start: 755542

End: 756549

Strand: Reverse

Name: desA1 [H]

Synonym: MAB_0754c

Alternate gene names: 169627855

Gene position: 756549-755542 (Counterclockwise)

Preceding gene: 169627856

Following gene: 169627854

Centisome position: 14.93

GC content: 63.89

Gene sequence:

>1008_bases
ATGTCGCAGAAGGAATTCACCGACCTCGAGCTGCTGCACGAGCTGGAGCCCGTGGTCGAGGAGAATGTCCACCGCCACCT
CGGTGTCACCAAGGACTGGAACCCGCACGATTACGTCCCGTGGTCGGAGGGCAAGAACTACAAGGCCCTGGGCGGGCAGG
ACTGGGATCCGGAGCAGTCCAAGCTCTCCGAGGTCGCCAAGATCGCGATGATCACCAACCTGCTCACCGAGGACAATCTG
CCCTCGTATCACCGCGAGATCGCCATGAACTTCACCATGGACGGCCCGTGGGGCACCTGGGTCAACCGCTGGACCGCCGA
GGAAAACCGGCACGGCATCGCCATCCGCGACTACCTGGTGGTCACCCGCTCGGTGGACCCGGTGGAACTGGAGAAACTGC
GCGTGGAGCAGATGACCCGCGGCTTCTCCCCCGGCCAGAACCGCCAGGGCGGCGACGAACTCTTCGCCGAGAGCCTGTTT
GACTCGGTGGTCTACGTGACCTTCCAGGAGCTGGCCACCCGCGTCTCGCACCGCAACACCGGTAAGGCCTGCGCCGAGCC
CGTCGCCGACGAGCTGCTCAAGCGCATCTCCACCGACGAGAACCTGCACATGATCTTCTACCGCAACCTTGTCGAGGCGG
GCATGCACATCGCTCCCGACCAGGCCCTGAAGTCCATCCATAAGGTGCTCGACAACTTCAAGATGCCCGGCTACACGATT
CCGGGGTTCCGCCGCAATGCCGTCACCATCGCCACCGGCGGTGTCTACGACCCGCAGTCGCACCTCGATGAGGTCGTCAT
GCCGGTGCTGCGCAAGTGGCGCATCTTCGAACGCGACGACATCAGCAGCGAGGGCGAGTGGTACCGCGAAGACCTCGACC
GGATCATCGGAGACCTCAAGAAGACGTCCGCGGACTTCGAAGAGGTCAAGGCCAAGTACCTGGAACGCCAGGCCAAGCGC
GCAGAACGCCAGGCCGCCAAGGCTGCCCGGGAAGCTGTCAGCGTCTAA

Upstream 100 bases:

>100_bases
GTGTGCCACGGCCGGTCCACTTGTATGCAACCGCCGTTTACAGATATATTGACTGCAACTTCCAGATACAGATAACTCTG
TCGAACCGAGGACCACATTC

Downstream 100 bases:

>100_bases
CCGGCTGTGACCGCATCTGTCGACCTACCAGAGGCCCGATCCCGCGAACTGCGGATCGGGTCTTTGGCATTGCCCAGCCC
GGTGGTGCTGGCCCCGATGG

Product: fatty acid desaturase

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA1 [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKALGGQDWDPEQSKLSEVAKIAMITNLLTEDNL
PSYHREIAMNFTMDGPWGTWVNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRVEQMTRGFSPGQNRQGGDELFAESLF
DSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDENLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTI
PGFRRNAVTIATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLKKTSADFEEVKAKYLERQAKR
AERQAAKAAREAVSV

Sequences:

>Translated_335_residues
MSQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKALGGQDWDPEQSKLSEVAKIAMITNLLTEDNL
PSYHREIAMNFTMDGPWGTWVNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRVEQMTRGFSPGQNRQGGDELFAESLF
DSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDENLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTI
PGFRRNAVTIATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLKKTSADFEEVKAKYLERQAKR
AERQAAKAAREAVSV
>Mature_334_residues
SQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKALGGQDWDPEQSKLSEVAKIAMITNLLTEDNLP
SYHREIAMNFTMDGPWGTWVNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRVEQMTRGFSPGQNRQGGDELFAESLFD
SVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDENLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTIP
GFRRNAVTIATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLKKTSADFEEVKAKYLERQAKRA
ERQAAKAAREAVSV

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 38499; Mature: 38368

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKALGGQDWDPEQS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KLSEVAKIAMITNLLTEDNLPSYHREIAMNFTMDGPWGTWVNRWTAEENRHGIAIRDYLV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHCCCCCCCCEEEEHHEE
VTRSVDPVELEKLRVEQMTRGFSPGQNRQGGDELFAESLFDSVVYVTFQELATRVSHRNT
EECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKACAEPVADELLKRISTDENLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTI
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
PGFRRNAVTIATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLK
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KTSADFEEVKAKYLERQAKRAERQAAKAAREAVSV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKALGGQDWDPEQS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KLSEVAKIAMITNLLTEDNLPSYHREIAMNFTMDGPWGTWVNRWTAEENRHGIAIRDYLV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHCCCCCCCCEEEEHHEE
VTRSVDPVELEKLRVEQMTRGFSPGQNRQGGDELFAESLFDSVVYVTFQELATRVSHRNT
EECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKACAEPVADELLKRISTDENLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTI
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
PGFRRNAVTIATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLK
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KTSADFEEVKAKYLERQAKRAERQAAKAAREAVSV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]