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The map label for this gene is msrR [H]

Identifier: 169627853

GI number: 169627853

Start: 751927

End: 754212

Strand: Reverse

Name: msrR [H]

Synonym: MAB_0752c

Alternate gene names: 169627853

Gene position: 754212-751927 (Counterclockwise)

Preceding gene: 169627854

Following gene: 169627852

Centisome position: 14.88

GC content: 65.7

Gene sequence:

>2286_bases
ATGGGTGATGGCCCAAACGCCACTCCTGCCCAACCACGCGCGTATGGCTCGGCCCCCTGGGAACGCGCGATCGAACCCGT
TGGCAGTCATCCTGACATCGACGTGGCGCCAGAACCATCCAACACACCGTGGACGCCACCGCCGGCTCTCAATCACTCAT
TGCCCGACCCCACCGACGACGAGTGGACGCGACGGCTCGAGACCGAACAATCCCTACGCGAACCGCGGCGGGCGGTGCCC
GAGGTACCGGCATCCCGGCCCGCCCGACCGGCCCCCAACGCAACGGCACCCACGGCCCCGCAGCCGCCGGCGCCCTCCGC
ACACGAGACCGGATCGCACTCGTTGTCGGTCGCCGATCTGCTGGCCCGTGAGGGCGCCAACGGCAGCCGTCGTTCACGTC
GGCACGCGCGCACCCAGGAGTCGGACGACTACGCAGAGGAGCCTGCTCCAGCGTCGTCCGCCGACGACAGCCACACAGAC
GTTCTCCCACAGGTGCACGAAGCCGCACCGCAGCGTGCTCAGTACACCGATGGGCCGGCCGACGAGCACCCGCCGTACGT
GGACTACCCCGATGACGCGCCCCTCTACGACAAGGCCGCCGCGCGTCGGGTTCGGGCATCGAATCTGGACGACAACATCG
ACACCCGCGCCATTCCCGTCCGGGTGGGCAACCCGGACGCCGCGGTCCGAGAAGAAGAACCGAAACGCTCACGGCGGCCC
ATCTACCTAGGACGCTCGATCGCCGCCGTCGTCGCGGTGTGTTCACTCACCGTGACCGGCGGTGCGTGGCAGTGGAGCAA
CGTCAAGAACAACAGGCTCAATCACGTTGAGGCGCTGGACCCCAACTCGCGCGACATCCGCGATCCCAACGCCCAGTACG
GCGACGAGAACTTCCTCATCATCGGCGTCGACACCCGTGCCGGCGCCAACAGCGCCATGGGCGCCGGCGACACCTCAGAC
GCTGAGGGCACACGCTCGGACACCATGATGTTGGTCAACATCCCGGCCAACCGTAAGCGCGTCGCGGTGGTGTCCTTCCC
CCGCGATCTGGCCATCCAGCCGACACTGTGCGAGGTCTGGAATGAGGACACCAAGTCCTATGGGCCCGATAAGGCCTACA
CCGAGACCAAACTCAACTCGGCGTTCGCCTTCGGCGGCCCCAAGTGCCTGGTCAAGGTCATCCAGAAGATGTCGGGACTG
AACATCAACCGCTTCCTCGGCGTGGATTTCGCCGGATTCTCCAAGATGGTCGACGCACTCGGTGGGGTCGAGGTGTGCAC
ACCCACACCGATCGAGGACTACGAGTTGGGCACGGTGCTGCAAAACGCCGGCCGCCAAACGATCGACGGCCACACCGCCC
TGCAGTATGTGCGGGCCCGCCAGGTCACCACCGAATACAACGGCGACTACGGACGCATCAAGCGCCAGCAGTTGTTCCTG
TCCTCCTTGCTGCGTTCGATGATTTCGCACAACACCTTCTTCTCGCTGAGCAAGCTCAACAACGTGGTGAACACCTTCAT
CGACGACTCCTATGTCGACAACATCAGGACGAAAGACCTTGTGGACCTTGGTCAGTCGCTTCAGGATGTGAAGGCTGGCC
GAATCACCTTCCTGACGGTGCCCACCGACGGCACCGACTCCGAGGGCAACGAGACACCGCGCACCACCGACATCCGGAAG
ATCTTCGACGCCATCATCAATGACGACCCGCTGCCCGGCGAGTTGCTGCCCGATGGCACCCGTGTTCCCATGCCAGGCAC
CACCACTCAGGACACCACCCTGGCCGCCAGCGAGCACGGAGCCGCCAGCGAGCTAGGCGAAACATCCACTGCCCCACCGA
CTCCCGCAGCAACACCCACCGAGCAGGTCGACCTGGTGACCACCGAACCCAGCGAGATCAACGTGCACGTGTCCAACAGC
ACGGGCCAAACCGGCCTGGCGGCGTCGGCGGCCAGCCAGCTGAGCAACTACGGCTTTGGCATCACCACCACCGACGACTA
CCCCTCGGCACTGCCCACCACCACCGTCTTCTTCTCGCCGGGCCACGAGCAACAGGCCGCGACGGTTGCCGCCTCATTCG
GCGGAGCCAAGCTGCAGCGGATCACCGGAGCCCAAACCACGGTGCGGGTGGTGCTCGGCAGCGACTACGCGTCTACCGCG
AACTTGCAGGCTCCGCCCGCGGCGGGTTCAACCGTCCCGCTGCAGCTGTCCTCGGGCGCAATGGCCCCCACCGAGCTGCC
GATGGACCTGACGGTCGTGAACGCCGGCGACACTAGCTGCGGATAG

Upstream 100 bases:

>100_bases
TCAGTAGCATGTGACGACGACCGTGCCCCGGGCACGGCGTTATCTGCTGCCGGTGTGCCGTGAACTTGCAACTGTCCAGA
CGTTTTAAGCGAGGTTGAAC

Downstream 100 bases:

>100_bases
TCCGACAATTTAGACGCTGCTCGCAGTTTCTTACGCGGACCCTGTAGTGGCATTCACTCGCCGTTCACACCAGGTCCATG
ACTCGACGGCGACGGGTCCG

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 760

Protein sequence:

>761_residues
MGDGPNATPAQPRAYGSAPWERAIEPVGSHPDIDVAPEPSNTPWTPPPALNHSLPDPTDDEWTRRLETEQSLREPRRAVP
EVPASRPARPAPNATAPTAPQPPAPSAHETGSHSLSVADLLAREGANGSRRSRRHARTQESDDYAEEPAPASSADDSHTD
VLPQVHEAAPQRAQYTDGPADEHPPYVDYPDDAPLYDKAAARRVRASNLDDNIDTRAIPVRVGNPDAAVREEEPKRSRRP
IYLGRSIAAVVAVCSLTVTGGAWQWSNVKNNRLNHVEALDPNSRDIRDPNAQYGDENFLIIGVDTRAGANSAMGAGDTSD
AEGTRSDTMMLVNIPANRKRVAVVSFPRDLAIQPTLCEVWNEDTKSYGPDKAYTETKLNSAFAFGGPKCLVKVIQKMSGL
NINRFLGVDFAGFSKMVDALGGVEVCTPTPIEDYELGTVLQNAGRQTIDGHTALQYVRARQVTTEYNGDYGRIKRQQLFL
SSLLRSMISHNTFFSLSKLNNVVNTFIDDSYVDNIRTKDLVDLGQSLQDVKAGRITFLTVPTDGTDSEGNETPRTTDIRK
IFDAIINDDPLPGELLPDGTRVPMPGTTTQDTTLAASEHGAASELGETSTAPPTPAATPTEQVDLVTTEPSEINVHVSNS
TGQTGLAASAASQLSNYGFGITTTDDYPSALPTTTVFFSPGHEQQAATVAASFGGAKLQRITGAQTTVRVVLGSDYASTA
NLQAPPAAGSTVPLQLSSGAMAPTELPMDLTVVNAGDTSCG

Sequences:

>Translated_761_residues
MGDGPNATPAQPRAYGSAPWERAIEPVGSHPDIDVAPEPSNTPWTPPPALNHSLPDPTDDEWTRRLETEQSLREPRRAVP
EVPASRPARPAPNATAPTAPQPPAPSAHETGSHSLSVADLLAREGANGSRRSRRHARTQESDDYAEEPAPASSADDSHTD
VLPQVHEAAPQRAQYTDGPADEHPPYVDYPDDAPLYDKAAARRVRASNLDDNIDTRAIPVRVGNPDAAVREEEPKRSRRP
IYLGRSIAAVVAVCSLTVTGGAWQWSNVKNNRLNHVEALDPNSRDIRDPNAQYGDENFLIIGVDTRAGANSAMGAGDTSD
AEGTRSDTMMLVNIPANRKRVAVVSFPRDLAIQPTLCEVWNEDTKSYGPDKAYTETKLNSAFAFGGPKCLVKVIQKMSGL
NINRFLGVDFAGFSKMVDALGGVEVCTPTPIEDYELGTVLQNAGRQTIDGHTALQYVRARQVTTEYNGDYGRIKRQQLFL
SSLLRSMISHNTFFSLSKLNNVVNTFIDDSYVDNIRTKDLVDLGQSLQDVKAGRITFLTVPTDGTDSEGNETPRTTDIRK
IFDAIINDDPLPGELLPDGTRVPMPGTTTQDTTLAASEHGAASELGETSTAPPTPAATPTEQVDLVTTEPSEINVHVSNS
TGQTGLAASAASQLSNYGFGITTTDDYPSALPTTTVFFSPGHEQQAATVAASFGGAKLQRITGAQTTVRVVLGSDYASTA
NLQAPPAAGSTVPLQLSSGAMAPTELPMDLTVVNAGDTSCG
>Mature_760_residues
GDGPNATPAQPRAYGSAPWERAIEPVGSHPDIDVAPEPSNTPWTPPPALNHSLPDPTDDEWTRRLETEQSLREPRRAVPE
VPASRPARPAPNATAPTAPQPPAPSAHETGSHSLSVADLLAREGANGSRRSRRHARTQESDDYAEEPAPASSADDSHTDV
LPQVHEAAPQRAQYTDGPADEHPPYVDYPDDAPLYDKAAARRVRASNLDDNIDTRAIPVRVGNPDAAVREEEPKRSRRPI
YLGRSIAAVVAVCSLTVTGGAWQWSNVKNNRLNHVEALDPNSRDIRDPNAQYGDENFLIIGVDTRAGANSAMGAGDTSDA
EGTRSDTMMLVNIPANRKRVAVVSFPRDLAIQPTLCEVWNEDTKSYGPDKAYTETKLNSAFAFGGPKCLVKVIQKMSGLN
INRFLGVDFAGFSKMVDALGGVEVCTPTPIEDYELGTVLQNAGRQTIDGHTALQYVRARQVTTEYNGDYGRIKRQQLFLS
SLLRSMISHNTFFSLSKLNNVVNTFIDDSYVDNIRTKDLVDLGQSLQDVKAGRITFLTVPTDGTDSEGNETPRTTDIRKI
FDAIINDDPLPGELLPDGTRVPMPGTTTQDTTLAASEHGAASELGETSTAPPTPAATPTEQVDLVTTEPSEINVHVSNST
GQTGLAASAASQLSNYGFGITTTDDYPSALPTTTVFFSPGHEQQAATVAASFGGAKLQRITGAQTTVRVVLGSDYASTAN
LQAPPAAGSTVPLQLSSGAMAPTELPMDLTVVNAGDTSCG

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 81311; Mature: 81180

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDGPNATPAQPRAYGSAPWERAIEPVGSHPDIDVAPEPSNTPWTPPPALNHSLPDPTDD
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EWTRRLETEQSLREPRRAVPEVPASRPARPAPNATAPTAPQPPAPSAHETGSHSLSVADL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LAREGANGSRRSRRHARTQESDDYAEEPAPASSADDSHTDVLPQVHEAAPQRAQYTDGPA
HHHCCCCCHHHHHHHHCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
DEHPPYVDYPDDAPLYDKAAARRVRASNLDDNIDTRAIPVRVGNPDAAVREEEPKRSRRP
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCC
IYLGRSIAAVVAVCSLTVTGGAWQWSNVKNNRLNHVEALDPNSRDIRDPNAQYGDENFLI
EEECHHHHHHHHHHHHEEECCCEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEE
IGVDTRAGANSAMGAGDTSDAEGTRSDTMMLVNIPANRKRVAVVSFPRDLAIQPTLCEVW
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHH
NEDTKSYGPDKAYTETKLNSAFAFGGPKCLVKVIQKMSGLNINRFLGVDFAGFSKMVDAL
CCHHHCCCCCCHHHHHHCCCEECCCCHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHH
GGVEVCTPTPIEDYELGTVLQNAGRQTIDGHTALQYVRARQVTTEYNGDYGRIKRQQLFL
CCCEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SSLLRSMISHNTFFSLSKLNNVVNTFIDDSYVDNIRTKDLVDLGQSLQDVKAGRITFLTV
HHHHHHHHHCCCEEEHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEE
PTDGTDSEGNETPRTTDIRKIFDAIINDDPLPGELLPDGTRVPMPGTTTQDTTLAASEHG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
AASELGETSTAPPTPAATPTEQVDLVTTEPSEINVHVSNSTGQTGLAASAASQLSNYGFG
CHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCC
ITTTDDYPSALPTTTVFFSPGHEQQAATVAASFGGAKLQRITGAQTTVRVVLGSDYASTA
EEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCCC
NLQAPPAAGSTVPLQLSSGAMAPTELPMDLTVVNAGDTSCG
CCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
GDGPNATPAQPRAYGSAPWERAIEPVGSHPDIDVAPEPSNTPWTPPPALNHSLPDPTDD
CCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EWTRRLETEQSLREPRRAVPEVPASRPARPAPNATAPTAPQPPAPSAHETGSHSLSVADL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LAREGANGSRRSRRHARTQESDDYAEEPAPASSADDSHTDVLPQVHEAAPQRAQYTDGPA
HHHCCCCCHHHHHHHHCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
DEHPPYVDYPDDAPLYDKAAARRVRASNLDDNIDTRAIPVRVGNPDAAVREEEPKRSRRP
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCC
IYLGRSIAAVVAVCSLTVTGGAWQWSNVKNNRLNHVEALDPNSRDIRDPNAQYGDENFLI
EEECHHHHHHHHHHHHEEECCCEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEE
IGVDTRAGANSAMGAGDTSDAEGTRSDTMMLVNIPANRKRVAVVSFPRDLAIQPTLCEVW
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHH
NEDTKSYGPDKAYTETKLNSAFAFGGPKCLVKVIQKMSGLNINRFLGVDFAGFSKMVDAL
CCHHHCCCCCCHHHHHHCCCEECCCCHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHH
GGVEVCTPTPIEDYELGTVLQNAGRQTIDGHTALQYVRARQVTTEYNGDYGRIKRQQLFL
CCCEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SSLLRSMISHNTFFSLSKLNNVVNTFIDDSYVDNIRTKDLVDLGQSLQDVKAGRITFLTV
HHHHHHHHHCCCEEEHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEE
PTDGTDSEGNETPRTTDIRKIFDAIINDDPLPGELLPDGTRVPMPGTTTQDTTLAASEHG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
AASELGETSTAPPTPAATPTEQVDLVTTEPSEINVHVSNSTGQTGLAASAASQLSNYGFG
CHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCC
ITTTDDYPSALPTTTVFFSPGHEQQAATVAASFGGAKLQRITGAQTTVRVVLGSDYASTA
EEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCCC
NLQAPPAAGSTVPLQLSSGAMAPTELPMDLTVVNAGDTSCG
CCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]