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The map label for this gene is ptrB [H]

Identifier: 169627792

GI number: 169627792

Start: 692207

End: 694342

Strand: Direct

Name: ptrB [H]

Synonym: MAB_0690

Alternate gene names: 169627792

Gene position: 692207-694342 (Clockwise)

Preceding gene: 169627791

Following gene: 169627793

Centisome position: 13.66

GC content: 63.34

Gene sequence:

>2136_bases
GTGAGCGGGCCGGTACGCCCGCCCGTCGCGAACCGTATCGACACTCTCCGCGAGTATCACGGGGACACCTTCGTCGATCC
GTATGAATGGATGCGTGAAAAGGAGACCCCCGAGGTCATCGCGTATTTAGAGGCGGAAAACGCCTATGTCGATGACCAGC
TTGGCCATCTGGCGGAGCTGCGCACCACCATCTTCGGTGAGATCAAGTCGCGCACCAAGGAGACCGACCTTTCGATCCCG
ACCCGGATGGGGCAGTGGTGGTACTACGCCCGCAGCTTCGAGGGAAAGCAGTACGGAGTTCATTGTCGTTGTCCGATAGG
GGATCCGAACGACTGGACACCGCCGGCCCTGGATCACGACGTTCCTGGTGAGCAGATCCTGCTCGACGGTAACGTGGAGG
CGGCAGGACACGACTTCTTCTCGCTCGGTGCCGCCACCGTCAGTCCGGACGGGAACACACTGGCCTATTCGGTCGACGTC
GTCGGCCATGAGATGTACACGCTGCGGTTCAAGAACCTGCGCACCGGCGAGATGTATCCGGACGAGATCGCCGATATCGG
CGCCGGTGCAACCTGGGCGATGGACAGCCGCACGCTCTACTATCCCGTGATCGATGAGGCCTTCCGGCCCTACGCCATTC
GCCGGTACACATTGGGTGGCGGCGCGGAACCCGTCGAGGTGTTCTCCGAACCGGACGAGCGATTCTGGATCGGGGTGGGC
CGCACCCGCAGTGATCGCTTTGTCGCCATTAGTGTGCATTCGTCGGTGACATCGGAGATCCTGATCGGGGACGCCGAGGA
TCCCGCGGCGACCTTTTCGCCAGTCTGGTTGCGCCGCAACGGTATCGAATACACCGTCGATCACATCGTGGTCGGCGGTG
AGGACAGGCTGCTGATTCTGCACAATGACGGCGCCGTGAATTTCGCGCTCGCGGAAATGCCGGTCGCCGCGGTGGTGGAC
GGACCGGCCGACCCGTCGGCGGCACGCACCCTGATCGCCCACCGCGATGATGTGCGGCTGGACGGGGTCGAGGCATTCGC
ACAGCGGTTCGTGATCGGGTACCGGCGAGAAGCATTGCCGCGCATTCAGGTCTGGCCCGTCACGGCCGACGGATACGGTT
CACCGCAGGAGGTCGAGTTCGACTCCGAGCTCATGCTCTCGGGATTGGGTGACAACCCGGAGTGGGATTCGCCGCTGCTG
CGGGTGGGTTGCGCATCGTTCATCACCCCCACCCGTGTCTACGACCTCGATGTGCACACCGGGGAGCGCACGCTGCTCAA
GGAGCAGCCCGTGCTCGGTGGCTATCGCCGCGAGGATTATGTGGAGCGGCGGGAATGGGCGCTCGCCGTAGATGGCACCC
GGGTGCCACTCTCAGTGGTCCACCGCAGAGGTATCACGTCACCGTCCCCGACCGTGCTGTACGGGTACGGCGCATACGAG
ATGTGTGAGGACCCCCAGTTCAGCATCGGCCGGCTCTCGTTGTTGGATCGGGGAGTGGTGTTCGTCATCGCTCACGTGCG
CGGTGGTGGTGAGATGGGCCGCCTCTGGTACGAGGACGGCAAGATGCTGCACAAGAAGCACAGCTTTTCCGATTTCGTAT
CGGCAGCAAGGCATCTCGTTGACTCAGGGGTCGCGCTGCCCAATCGGCTGGTCGCCTGGGGCGGCAGCGCGGGCGGGCTG
TTGGTGGGTGCCGCGGTAAACCTGGCACCCGAGCTGTTCGCCGGTGTGCTGGCGCAGGTGCCCTTCGTCGACCCCGTCAC
CACCATTTGCGATCCCTCGCTACCGCTCACCGTCACCGAGTGGGATGAGTGGGGAAATCCCCTGGAAAACAAGGATGTTT
ACGACTACATCAAGTCGTACTCGCCCTACGAGAACATCCGCGCCGCCGACTATCCGAGCATTCTCGCGATGACATCGCTG
CATGACTCGCGGGTGCTGTACGTCGAACCCGCCAAATGGGTGGCCGAACTGCGCCACACCACCACCGGTGAGCGACCCAT
CCTGTTGAAGACCGAGATGACGGCGGGGCACGGCGGGATAAGCGGCCGCTATGAACGCTGGAAGGAAAGCGCTTTCCAGC
TCGCCTGGCTACTGGATATCCTTGGAGCGCAGGGGGAGACGCCGAATGCCCGATGA

Upstream 100 bases:

>100_bases
CGTTGCCAGATGAGGTGGCAGTGGCCACGCGGGAACGTTATATCGAGGCCTATGAGCGCATTTCAGGGCTGAGCTTCTCT
GATTGGATTGGCCCGTCGGC

Downstream 100 bases:

>100_bases
GGTCGTCGTCGTCATCGGCGTCGGCGGGATGGGCAGGGTCATCGCCCGTCGTCAGGGCATCGGCAAGGCGCTGCTGCTCG
CCGACCACAACGAGCAGGCG

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MSGPVRPPVANRIDTLREYHGDTFVDPYEWMREKETPEVIAYLEAENAYVDDQLGHLAELRTTIFGEIKSRTKETDLSIP
TRMGQWWYYARSFEGKQYGVHCRCPIGDPNDWTPPALDHDVPGEQILLDGNVEAAGHDFFSLGAATVSPDGNTLAYSVDV
VGHEMYTLRFKNLRTGEMYPDEIADIGAGATWAMDSRTLYYPVIDEAFRPYAIRRYTLGGGAEPVEVFSEPDERFWIGVG
RTRSDRFVAISVHSSVTSEILIGDAEDPAATFSPVWLRRNGIEYTVDHIVVGGEDRLLILHNDGAVNFALAEMPVAAVVD
GPADPSAARTLIAHRDDVRLDGVEAFAQRFVIGYRREALPRIQVWPVTADGYGSPQEVEFDSELMLSGLGDNPEWDSPLL
RVGCASFITPTRVYDLDVHTGERTLLKEQPVLGGYRREDYVERREWALAVDGTRVPLSVVHRRGITSPSPTVLYGYGAYE
MCEDPQFSIGRLSLLDRGVVFVIAHVRGGGEMGRLWYEDGKMLHKKHSFSDFVSAARHLVDSGVALPNRLVAWGGSAGGL
LVGAAVNLAPELFAGVLAQVPFVDPVTTICDPSLPLTVTEWDEWGNPLENKDVYDYIKSYSPYENIRAADYPSILAMTSL
HDSRVLYVEPAKWVAELRHTTTGERPILLKTEMTAGHGGISGRYERWKESAFQLAWLLDILGAQGETPNAR

Sequences:

>Translated_711_residues
MSGPVRPPVANRIDTLREYHGDTFVDPYEWMREKETPEVIAYLEAENAYVDDQLGHLAELRTTIFGEIKSRTKETDLSIP
TRMGQWWYYARSFEGKQYGVHCRCPIGDPNDWTPPALDHDVPGEQILLDGNVEAAGHDFFSLGAATVSPDGNTLAYSVDV
VGHEMYTLRFKNLRTGEMYPDEIADIGAGATWAMDSRTLYYPVIDEAFRPYAIRRYTLGGGAEPVEVFSEPDERFWIGVG
RTRSDRFVAISVHSSVTSEILIGDAEDPAATFSPVWLRRNGIEYTVDHIVVGGEDRLLILHNDGAVNFALAEMPVAAVVD
GPADPSAARTLIAHRDDVRLDGVEAFAQRFVIGYRREALPRIQVWPVTADGYGSPQEVEFDSELMLSGLGDNPEWDSPLL
RVGCASFITPTRVYDLDVHTGERTLLKEQPVLGGYRREDYVERREWALAVDGTRVPLSVVHRRGITSPSPTVLYGYGAYE
MCEDPQFSIGRLSLLDRGVVFVIAHVRGGGEMGRLWYEDGKMLHKKHSFSDFVSAARHLVDSGVALPNRLVAWGGSAGGL
LVGAAVNLAPELFAGVLAQVPFVDPVTTICDPSLPLTVTEWDEWGNPLENKDVYDYIKSYSPYENIRAADYPSILAMTSL
HDSRVLYVEPAKWVAELRHTTTGERPILLKTEMTAGHGGISGRYERWKESAFQLAWLLDILGAQGETPNAR
>Mature_710_residues
SGPVRPPVANRIDTLREYHGDTFVDPYEWMREKETPEVIAYLEAENAYVDDQLGHLAELRTTIFGEIKSRTKETDLSIPT
RMGQWWYYARSFEGKQYGVHCRCPIGDPNDWTPPALDHDVPGEQILLDGNVEAAGHDFFSLGAATVSPDGNTLAYSVDVV
GHEMYTLRFKNLRTGEMYPDEIADIGAGATWAMDSRTLYYPVIDEAFRPYAIRRYTLGGGAEPVEVFSEPDERFWIGVGR
TRSDRFVAISVHSSVTSEILIGDAEDPAATFSPVWLRRNGIEYTVDHIVVGGEDRLLILHNDGAVNFALAEMPVAAVVDG
PADPSAARTLIAHRDDVRLDGVEAFAQRFVIGYRREALPRIQVWPVTADGYGSPQEVEFDSELMLSGLGDNPEWDSPLLR
VGCASFITPTRVYDLDVHTGERTLLKEQPVLGGYRREDYVERREWALAVDGTRVPLSVVHRRGITSPSPTVLYGYGAYEM
CEDPQFSIGRLSLLDRGVVFVIAHVRGGGEMGRLWYEDGKMLHKKHSFSDFVSAARHLVDSGVALPNRLVAWGGSAGGLL
VGAAVNLAPELFAGVLAQVPFVDPVTTICDPSLPLTVTEWDEWGNPLENKDVYDYIKSYSPYENIRAADYPSILAMTSLH
DSRVLYVEPAKWVAELRHTTTGERPILLKTEMTAGHGGISGRYERWKESAFQLAWLLDILGAQGETPNAR

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=715, Percent_Identity=23.4965034965035, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI284172420, Length=521, Percent_Identity=27.6391554702495, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI284172413, Length=521, Percent_Identity=27.6391554702495, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI70778815, Length=521, Percent_Identity=27.6391554702495, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI284172438, Length=454, Percent_Identity=29.295154185022, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI284172431, Length=454, Percent_Identity=29.295154185022, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI108860686, Length=204, Percent_Identity=37.7450980392157, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI108860692, Length=197, Percent_Identity=38.0710659898477, Blast_Score=125, Evalue=1e-28,
Organism=Escherichia coli, GI1788150, Length=711, Percent_Identity=37.4120956399437, Blast_Score=437, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24583414, Length=737, Percent_Identity=24.8303934871099, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI221510989, Length=698, Percent_Identity=25.0716332378224, Blast_Score=177, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 79028; Mature: 78896

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPVRPPVANRIDTLREYHGDTFVDPYEWMREKETPEVIAYLEAENAYVDDQLGHLAEL
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHH
RTTIFGEIKSRTKETDLSIPTRMGQWWYYARSFEGKQYGVHCRCPIGDPNDWTPPALDHD
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEECEEEECCCCCCCCCCCCCCCCC
VPGEQILLDGNVEAAGHDFFSLGAATVSPDGNTLAYSVDVVGHEMYTLRFKNLRTGEMYP
CCCCEEEEECCCCCCCCCCEECCCEEECCCCCEEEEEEEEECCEEEEEEECCCCCCCCCC
DEIADIGAGATWAMDSRTLYYPVIDEAFRPYAIRRYTLGGGAEPVEVFSEPDERFWIGVG
HHHHHCCCCCEEEECCCEEEEEEHHHCCCCEEEEEEECCCCCCHHHHHCCCCCEEEEECC
RTRSDRFVAISVHSSVTSEILIGDAEDPAATFSPVWLRRNGIEYTVDHIVVGGEDRLLIL
CCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEECCCCEEEEE
HNDGAVNFALAEMPVAAVVDGPADPSAARTLIAHRDDVRLDGVEAFAQRFVIGYRREALP
ECCCCEEEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
RIQVWPVTADGYGSPQEVEFDSELMLSGLGDNPEWDSPLLRVGCASFITPTRVYDLDVHT
CEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCC
GERTLLKEQPVLGGYRREDYVERREWALAVDGTRVPLSVVHRRGITSPSPTVLYGYGAYE
CCHHHHHCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCCCCEEEEECCCHH
MCEDPQFSIGRLSLLDRGVVFVIAHVRGGGEMGRLWYEDGKMLHKKHSFSDFVSAARHLV
HCCCCCCCCCHHHHHCCCEEEEEEEECCCCCCCCEEECCCHHHHHHCCHHHHHHHHHHHH
DSGVALPNRLVAWGGSAGGLLVGAAVNLAPELFAGVLAQVPFVDPVTTICDPSLPLTVTE
HCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEC
WDEWGNPLENKDVYDYIKSYSPYENIRAADYPSILAMTSLHDSRVLYVEPAKWVAELRHT
HHHCCCCCCCCHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHC
TTGERPILLKTEMTAGHGGISGRYERWKESAFQLAWLLDILGAQGETPNAR
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SGPVRPPVANRIDTLREYHGDTFVDPYEWMREKETPEVIAYLEAENAYVDDQLGHLAEL
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHH
RTTIFGEIKSRTKETDLSIPTRMGQWWYYARSFEGKQYGVHCRCPIGDPNDWTPPALDHD
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEECEEEECCCCCCCCCCCCCCCCC
VPGEQILLDGNVEAAGHDFFSLGAATVSPDGNTLAYSVDVVGHEMYTLRFKNLRTGEMYP
CCCCEEEEECCCCCCCCCCEECCCEEECCCCCEEEEEEEEECCEEEEEEECCCCCCCCCC
DEIADIGAGATWAMDSRTLYYPVIDEAFRPYAIRRYTLGGGAEPVEVFSEPDERFWIGVG
HHHHHCCCCCEEEECCCEEEEEEHHHCCCCEEEEEEECCCCCCHHHHHCCCCCEEEEECC
RTRSDRFVAISVHSSVTSEILIGDAEDPAATFSPVWLRRNGIEYTVDHIVVGGEDRLLIL
CCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEECCCCEEEEE
HNDGAVNFALAEMPVAAVVDGPADPSAARTLIAHRDDVRLDGVEAFAQRFVIGYRREALP
ECCCCEEEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
RIQVWPVTADGYGSPQEVEFDSELMLSGLGDNPEWDSPLLRVGCASFITPTRVYDLDVHT
CEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCC
GERTLLKEQPVLGGYRREDYVERREWALAVDGTRVPLSVVHRRGITSPSPTVLYGYGAYE
CCHHHHHCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCCCCEEEEECCCHH
MCEDPQFSIGRLSLLDRGVVFVIAHVRGGGEMGRLWYEDGKMLHKKHSFSDFVSAARHLV
HCCCCCCCCCHHHHHCCCEEEEEEEECCCCCCCCEEECCCHHHHHHCCHHHHHHHHHHHH
DSGVALPNRLVAWGGSAGGLLVGAAVNLAPELFAGVLAQVPFVDPVTTICDPSLPLTVTE
HCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEC
WDEWGNPLENKDVYDYIKSYSPYENIRAADYPSILAMTSLHDSRVLYVEPAKWVAELRHT
HHHCCCCCCCCHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHC
TTGERPILLKTEMTAGHGGISGRYERWKESAFQLAWLLDILGAQGETPNAR
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]