Click here to switch to the map view.

The map label for this gene is acdA [H]

Identifier: 169627698

GI number: 169627698

Start: 595416

End: 596576

Strand: Reverse

Name: acdA [H]

Synonym: MAB_0595c

Alternate gene names: 169627698

Gene position: 596576-595416 (Counterclockwise)

Preceding gene: 169627699

Following gene: 169627697

Centisome position: 11.77

GC content: 64.25

Gene sequence:

>1161_bases
GTGGACCTACTTCTTGACGATGAGACCGAGGCGTTCCGGGCCGAGGTCCGCGAGTTCCTCGTATCCAATGTCCCCAATCC
GCCGCTGCCGTCCTATGACTCACCGGAAGGTGCGGCGGCACACCGGCAATGGGAACGCACCCTGTACGACGCGGGATTCT
CCGCCGTGTCCTGGCCCAAGGAATACGGCGGCCGAGATGTCACGCCGCTGCAGTGGGTGATCTTCGAAGAGGAATACTTC
AAGGCCGGTGCGCCCGCGCGCATCAGCCAGAACGGCATGTTCTTGTTGGGGCCGACGCTGTTCGCCCACGGCAGCAAGGA
CCAGCTGGATCGCGTGCTTCCGAAGATGGCCAACGGGGAAGAGATCTGGGCACAGGCATGGTCCGAGCCCGAGTCCGGCA
GCGACCTGGCGTCGCTGCGCTCCCCCGCTCGAAAGGTGGACGGGGGCTGGCGTCTGTCTGGCCAGAAGATCTGGAGTTCA
CGAGCGCCCTTCGCGGACAGAGCATTCGGCTTGTTCCGTTCCGATCCGGACGCGCAGCGCCATCAGGGTCTGACGTATTT
CATGTTTGATCTGAAGGCGGAGGGCATCACCGTGCGCCCGATCCCGCAGCTCGACGGTGATCCCGGGTTCGCGGAAATCT
TCCTGGACGACGTGTTTGTGCCCGATGAAGACGTCATCGGCGCGGTGCATGACGGCTGGCGCGTGGCGATGAGCACCTCG
AGCAACGAGCGTGGCATGTCGCTACGCAGCCCCGGACGCTTCCTGGCCACCGCAGACCGCCTGGTCGAGCTGTGGAAATC
GGTTCCGGAGAACGAGTTCGCATCCGAACGCGTTGCCGACGCCTGGATCGCGGCGCAGGCATACCGGCTGCACACATTTG
GCACCGTGACCCGGCTGGCCGGTGGCGGGGAGCTTGGCGCCGAATCCTCGATCACCAAGGTGTTCTGGTCCGAGCTCGAT
GTCGCCTTGCACGAGACCGCAATCGACCTGCGCGGGGCCGAGGGCGAGTTGACGAATGCTTGGACGGACGGATACCTGTT
CTCGCTCGGCGGTCCGATTTATGCGGGCACCAACGAGATTCAGCGCAATATCATCGCCGAGCGCATCCTGGGCCTACCCA
GAGAAAGCAGCGCAAGCGCTCGCACGGGAGGTGCCAAGTGA

Upstream 100 bases:

>100_bases
TCCTCGATGAGCTTCCCCGCAACCTGGGCGGCAAGGTGGTCAAGCCCACGCTGCGGGCCATGCATGGCGAACAGCGCAGG
GCACAGAAGGAGAGCAGTTA

Downstream 100 bases:

>100_bases
AATTCGATCTGGACACCCAACAGCGCGACTTCGCCGCCAGCATCGACGCGGCGCTGTCGGTAGCCGATGTTCCGGCCGCG
GCGCGTGCCTGGGCCGCGGG

Product: acyl-CoA dehydrogenase FadE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDLLLDDETEAFRAEVREFLVSNVPNPPLPSYDSPEGAAAHRQWERTLYDAGFSAVSWPKEYGGRDVTPLQWVIFEEEYF
KAGAPARISQNGMFLLGPTLFAHGSKDQLDRVLPKMANGEEIWAQAWSEPESGSDLASLRSPARKVDGGWRLSGQKIWSS
RAPFADRAFGLFRSDPDAQRHQGLTYFMFDLKAEGITVRPIPQLDGDPGFAEIFLDDVFVPDEDVIGAVHDGWRVAMSTS
SNERGMSLRSPGRFLATADRLVELWKSVPENEFASERVADAWIAAQAYRLHTFGTVTRLAGGGELGAESSITKVFWSELD
VALHETAIDLRGAEGELTNAWTDGYLFSLGGPIYAGTNEIQRNIIAERILGLPRESSASARTGGAK

Sequences:

>Translated_386_residues
MDLLLDDETEAFRAEVREFLVSNVPNPPLPSYDSPEGAAAHRQWERTLYDAGFSAVSWPKEYGGRDVTPLQWVIFEEEYF
KAGAPARISQNGMFLLGPTLFAHGSKDQLDRVLPKMANGEEIWAQAWSEPESGSDLASLRSPARKVDGGWRLSGQKIWSS
RAPFADRAFGLFRSDPDAQRHQGLTYFMFDLKAEGITVRPIPQLDGDPGFAEIFLDDVFVPDEDVIGAVHDGWRVAMSTS
SNERGMSLRSPGRFLATADRLVELWKSVPENEFASERVADAWIAAQAYRLHTFGTVTRLAGGGELGAESSITKVFWSELD
VALHETAIDLRGAEGELTNAWTDGYLFSLGGPIYAGTNEIQRNIIAERILGLPRESSASARTGGAK
>Mature_386_residues
MDLLLDDETEAFRAEVREFLVSNVPNPPLPSYDSPEGAAAHRQWERTLYDAGFSAVSWPKEYGGRDVTPLQWVIFEEEYF
KAGAPARISQNGMFLLGPTLFAHGSKDQLDRVLPKMANGEEIWAQAWSEPESGSDLASLRSPARKVDGGWRLSGQKIWSS
RAPFADRAFGLFRSDPDAQRHQGLTYFMFDLKAEGITVRPIPQLDGDPGFAEIFLDDVFVPDEDVIGAVHDGWRVAMSTS
SNERGMSLRSPGRFLATADRLVELWKSVPENEFASERVADAWIAAQAYRLHTFGTVTRLAGGGELGAESSITKVFWSELD
VALHETAIDLRGAEGELTNAWTDGYLFSLGGPIYAGTNEIQRNIIAERILGLPRESSASARTGGAK

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI76496475, Length=348, Percent_Identity=27.8735632183908, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI4557235, Length=348, Percent_Identity=27.8735632183908, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=24.0105540897098, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226958414, Length=366, Percent_Identity=24.5901639344262, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4557233, Length=332, Percent_Identity=26.5060240963855, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=23.8726790450928, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4501857, Length=389, Percent_Identity=24.4215938303342, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI21361497, Length=401, Percent_Identity=26.9326683291771, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI187960098, Length=382, Percent_Identity=24.0837696335079, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557231, Length=382, Percent_Identity=24.0837696335079, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=23.3766233766234, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786223, Length=348, Percent_Identity=21.8390804597701, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=25.1322751322751, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=392, Percent_Identity=27.5510204081633, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=380, Percent_Identity=23.9473684210526, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=358, Percent_Identity=24.5810055865922, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=336, Percent_Identity=23.2142857142857, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=357, Percent_Identity=24.3697478991597, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=302, Percent_Identity=27.1523178807947, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=24.2666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71985192, Length=170, Percent_Identity=31.1764705882353, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=389, Percent_Identity=23.3933161953728, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=24.802110817942, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21356377, Length=338, Percent_Identity=26.0355029585799, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=27.7142857142857, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21355753, Length=386, Percent_Identity=24.0932642487047, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666513, Length=336, Percent_Identity=24.4047619047619, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24660351, Length=341, Percent_Identity=23.4604105571848, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42530; Mature: 42530

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLDDETEAFRAEVREFLVSNVPNPPLPSYDSPEGAAAHRQWERTLYDAGFSAVSWPK
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHH
EYGGRDVTPLQWVIFEEEYFKAGAPARISQNGMFLLGPTLFAHGSKDQLDRVLPKMANGE
HHCCCCCCCEEEEEEEHHHHCCCCCCEECCCCEEEECCHHHCCCCHHHHHHHHHHCCCCH
EIWAQAWSEPESGSDLASLRSPARKVDGGWRLSGQKIWSSRAPFADRAFGLFRSDPDAQR
HHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHCCCCCCHHHHHHHHCCCCCHHH
HQGLTYFMFDLKAEGITVRPIPQLDGDPGFAEIFLDDVFVPDEDVIGAVHDGWRVAMSTS
HCCCEEEEEEEECCCEEEECCCCCCCCCCHHHEEECCCCCCCHHHEEEECCCEEEEEECC
SNERGMSLRSPGRFLATADRLVELWKSVPENEFASERVADAWIAAQAYRLHTFGTVTRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGGELGAESSITKVFWSELDVALHETAIDLRGAEGELTNAWTDGYLFSLGGPIYAGTNEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEECCCCEECCHHHH
QRNIIAERILGLPRESSASARTGGAK
HHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLLLDDETEAFRAEVREFLVSNVPNPPLPSYDSPEGAAAHRQWERTLYDAGFSAVSWPK
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHH
EYGGRDVTPLQWVIFEEEYFKAGAPARISQNGMFLLGPTLFAHGSKDQLDRVLPKMANGE
HHCCCCCCCEEEEEEEHHHHCCCCCCEECCCCEEEECCHHHCCCCHHHHHHHHHHCCCCH
EIWAQAWSEPESGSDLASLRSPARKVDGGWRLSGQKIWSSRAPFADRAFGLFRSDPDAQR
HHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHCCCCCCHHHHHHHHCCCCCHHH
HQGLTYFMFDLKAEGITVRPIPQLDGDPGFAEIFLDDVFVPDEDVIGAVHDGWRVAMSTS
HCCCEEEEEEEECCCEEEECCCCCCCCCCHHHEEECCCCCCCHHHEEEECCCEEEEEECC
SNERGMSLRSPGRFLATADRLVELWKSVPENEFASERVADAWIAAQAYRLHTFGTVTRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGGELGAESSITKVFWSELDVALHETAIDLRGAEGELTNAWTDGYLFSLGGPIYAGTNEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEECCCCEECCHHHH
QRNIIAERILGLPRESSASARTGGAK
HHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]