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The map label for this gene is yngJ [H]

Identifier: 169627697

GI number: 169627697

Start: 594454

End: 595419

Strand: Reverse

Name: yngJ [H]

Synonym: MAB_0594c

Alternate gene names: 169627697

Gene position: 595419-594454 (Counterclockwise)

Preceding gene: 169627698

Following gene: 169627696

Centisome position: 11.75

GC content: 66.98

Gene sequence:

>966_bases
GTGAAATTCGATCTGGACACCCAACAGCGCGACTTCGCCGCCAGCATCGACGCGGCGCTGTCGGTAGCCGATGTTCCGGC
CGCGGCGCGTGCCTGGGCCGCGGGTAATCACGGCCCCGGCCTGGCGGTGTGGTCCACGCTCGCCGAACTCGGCGTCACCG
CCCTCGCGGTATCCGAGAAGTACGACGGCATCGGGGCACATCCCGTGGATCTGGTTGTTGCCCTTGAAGGCTTGGGCAAG
TGGGCCGTGCCCGGCCCAGTCGTCGAGTCGGTCGCGGTGGCCCCGGTGTTGCTGTCCAGCCACGAGGACGGAGCGGAGCC
GTCCACACGTCTTGCCTCCGGCGAATTGATCGCCACGGTCGCCGCGCCACCGATCGCCCCCCGCGCCCTGGACGCCGACA
TCGCCGGGCTCGTGCTCATCGCCGACGACATCGGCATCCGCGAGGCGCAGGCCGGCGCGCAGCACGAATCGATTGATGCG
ACCCGCCGTGTCTTCGACGTCCAACCGAAGGAAGCCGGTATCTCACTCGACACCAGTCGCGCCATCGACTTTGGTGTGCT
TGCCATTTCGGCGCAGCTGATCGGGGCCGGACAAGCCCTGCTGGACCGTGCCGTAGCGTACGCCAAACAGCGTTCTCAAT
TCGGCCGTCCGATCGGCTCGTACCAGGCCGTGAAGCACAAGCTGGCCGATGTGCACATCGCACTGGAGCTGGCCCGGCCC
CTGGTATACGGCGCAGCACTGTCCCTCGCTGACCAATCCCCCACTGCCGCACGCGATGCCAGTGCCGCGAAGGTCGCCGC
GGCTAAGGCCGCATACCTCGCTGCCCGCTCCGCCCTGCAGACGCATGGCGCCATTGGTTTTACCGCCGAATACGACCTGT
CGTTGTGGATCCTCAAGGTACGGGCACTGACCTCGGCATGGGGTACCTCGGAATGGCACCGTGCACGAGTGTTGGAGGCA
CTGTGA

Upstream 100 bases:

>100_bases
TTTATGCGGGCACCAACGAGATTCAGCGCAATATCATCGCCGAGCGCATCCTGGGCCTACCCAGAGAAAGCAGCGCAAGC
GCTCGCACGGGAGGTGCCAA

Downstream 100 bases:

>100_bases
GTCCTTCCGGAAACACCGAACGGCAGATGCTGCGCGACACGGTCCGGTCTCTGGTCACCAAGCGGGCCGACTCCGCAGCG
GTCCGCACCGCGTTCGAATC

Product: acyl-CoA dehydrogenase FadE

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPGLAVWSTLAELGVTALAVSEKYDGIGAHPVDLVVALEGLGK
WAVPGPVVESVAVAPVLLSSHEDGAEPSTRLASGELIATVAAPPIAPRALDADIAGLVLIADDIGIREAQAGAQHESIDA
TRRVFDVQPKEAGISLDTSRAIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLADVHIALELARP
LVYGAALSLADQSPTAARDASAAKVAAAKAAYLAARSALQTHGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEA
L

Sequences:

>Translated_321_residues
MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPGLAVWSTLAELGVTALAVSEKYDGIGAHPVDLVVALEGLGK
WAVPGPVVESVAVAPVLLSSHEDGAEPSTRLASGELIATVAAPPIAPRALDADIAGLVLIADDIGIREAQAGAQHESIDA
TRRVFDVQPKEAGISLDTSRAIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLADVHIALELARP
LVYGAALSLADQSPTAARDASAAKVAAAKAAYLAARSALQTHGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEA
L
>Mature_321_residues
MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPGLAVWSTLAELGVTALAVSEKYDGIGAHPVDLVVALEGLGK
WAVPGPVVESVAVAPVLLSSHEDGAEPSTRLASGELIATVAAPPIAPRALDADIAGLVLIADDIGIREAQAGAQHESIDA
TRRVFDVQPKEAGISLDTSRAIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLADVHIALELARP
LVYGAALSLADQSPTAARDASAAKVAAAKAAYLAARSALQTHGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEA
L

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=135, Percent_Identity=36.2962962962963, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4501859, Length=117, Percent_Identity=31.6239316239316, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=132, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=134, Percent_Identity=34.3283582089552, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506239, Length=111, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=134, Percent_Identity=34.3283582089552, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356377, Length=135, Percent_Identity=36.2962962962963, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646207, Length=135, Percent_Identity=32.5925925925926, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24666513, Length=137, Percent_Identity=28.4671532846715, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 33263; Mature: 33263

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPGLAVWSTLAELGVTALAVSEK
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCHHEEEECCC
YDGIGAHPVDLVVALEGLGKWAVPGPVVESVAVAPVLLSSHEDGAEPSTRLASGELIATV
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEEEE
AAPPIAPRALDADIAGLVLIADDIGIREAQAGAQHESIDATRRVFDVQPKEAGISLDTSR
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHEECCCHHCCCCCCCCC
AIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLADVHIALELARP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LVYGAALSLADQSPTAARDASAAKVAAAKAAYLAARSALQTHGAIGFTAEYDLSLWILKV
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHHH
RALTSAWGTSEWHRARVLEAL
HHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPGLAVWSTLAELGVTALAVSEK
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCHHEEEECCC
YDGIGAHPVDLVVALEGLGKWAVPGPVVESVAVAPVLLSSHEDGAEPSTRLASGELIATV
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEEEE
AAPPIAPRALDADIAGLVLIADDIGIREAQAGAQHESIDATRRVFDVQPKEAGISLDTSR
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHEECCCHHCCCCCCCCC
AIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLADVHIALELARP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LVYGAALSLADQSPTAARDASAAKVAAAKAAYLAARSALQTHGAIGFTAEYDLSLWILKV
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHHH
RALTSAWGTSEWHRARVLEAL
HHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]