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The map label for this gene is cysS [H]

Identifier: 169627674

GI number: 169627674

Start: 570012

End: 571451

Strand: Direct

Name: cysS [H]

Synonym: MAB_0571

Alternate gene names: 169627674

Gene position: 570012-571451 (Clockwise)

Preceding gene: 169627673

Following gene: 169627675

Centisome position: 11.25

GC content: 63.68

Gene sequence:

>1440_bases
GTGACCGGTCACGTTCCGCTTCGGCTGTACGACACCCGTGTGGGTGCCGTGCGTGACTTCGTGCCGCTGCAGCCCGGGAC
CGTCTCCATCTACCTGTGCGGGGCAACCGTGCAGGGTCTGCCCCATATCGGACATGTGCGCAGCGGTGTGGCCTTCGATG
TGTTGCGCCGCTGGCTCAGCGCCCGCGCTTATGACGTTTTGTTTGTCCGGAACGTCACCGACATCGACGACAAGATCCTG
AACAAGGCGGCCGATGCCGGCCGGCCGTGGTGGGAATGGGCAGCGACATACGAGCGCGCCTTCGACGAGGCGTACGAGTC
CCTCGGGGTGCTGCCGCCCTCGGTGTCCCCGCGCGCCACGGGGCATATCACCCAGATGATCGAGCTGATCGATCGGCTCA
TAGAAAGAGGACACGCCTACCGGGACCTCAGAGAGGGCGGCGGCGACGTCTACTTCGACGTGTTGAGCTATCCCGAATAC
GGGCAATTGTCCGGGCACAAGATCGACGATGTCCATCAGGGCGAGGGGGTTGCCACCGGAAAACGCGATCCGCGTGACTT
CACCTTGTGGAAGGGCGCCAAGCCCGGTGAACCGTCGTGGCCCACGCCGTGGGGTCCGGGTCGTCCCGGGTGGCACCTGG
AATGCTCAGCGATGGCGCGCACATATCTCGGACCTAGCTTCGATATCCACTGTGGTGGAATGGATTTGGTCTTCCCGCAC
CATGAGAACGAAATTGCGCAGAGCTGTGCGGCCGGGGACGGGTTCGCCCGTTACTGGATGCACAATGGCTGGGTCACCAT
GGGCGGTGAGAAGATGAGCAAGTCGCTGGGCAACGTGCTGTCCATTCCGGCTGTGCTGCAACGTGTTCGGGCAGTCGAAC
TACGCTACTACCTGGGTAGCGCGCACTACCGTTCGATGCTCGAGTACTCCGAGACCGCGCTCGCCGATGCGGTGAAGGCC
TATTGCGGTATCGAAGACTTTCTGCATCGGGTACGGATCCGCGTCGGAGACGTGCCGGTGGGCACCTGGACGCCGGCGTT
CGCCGCAGCCCTGGACGACGATCTCTCGGTGCCGATCGCGCTGGCCGAGGTGCATTCCACCCGGGCCGATGGAAACCGGG
CGCTCGATGCCGGTGATCACGAGGGTGCGCTGTCGGCGGCGGCCAGCATTCGGGCCATGATGTCGATTCTCGGTTGCGAT
CCGCTTGATGAGCGCTGGGAGACCCGCGATGAGACCTCTGCCGCGCTGAACGCGGTCGACGTATTGGTGACAGCGGAGCT
ACAGCGGCGCGAAACGGCACGGACAGAAAAGAACTGGGCACTGGCCGACGAGATCAGAGATCGGCTCAAGCGCGCGGGTC
TGGAGATCACCGACACGGCCGATGGCCCGCAATGGACCCTTACCAGTAGCGACGAAGAGCAGTACCATCATGGCAGGTAA

Upstream 100 bases:

>100_bases
TATCGGCAACCACCACCGACGGGCTGGGTCTGACCGGACGCGGCGAAGGGTTGGCCGCGGTGGCAACGGCGCTCGTCACA
GCGCTGTAAGCTCGCTGGTC

Downstream 100 bases:

>100_bases
TTCGCAGCGCCGCGGCGCGGTACGTAAGCCCGGCACCAAAAAGGGCCCCACTGTCGGCTCGGGCGGCGTGCGCCGCCGCG
GGCTGGAGGGCAAGGGGGCG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTGHVPLRLYDTRVGAVRDFVPLQPGTVSIYLCGATVQGLPHIGHVRSGVAFDVLRRWLSARAYDVLFVRNVTDIDDKIL
NKAADAGRPWWEWAATYERAFDEAYESLGVLPPSVSPRATGHITQMIELIDRLIERGHAYRDLREGGGDVYFDVLSYPEY
GQLSGHKIDDVHQGEGVATGKRDPRDFTLWKGAKPGEPSWPTPWGPGRPGWHLECSAMARTYLGPSFDIHCGGMDLVFPH
HENEIAQSCAAGDGFARYWMHNGWVTMGGEKMSKSLGNVLSIPAVLQRVRAVELRYYLGSAHYRSMLEYSETALADAVKA
YCGIEDFLHRVRIRVGDVPVGTWTPAFAAALDDDLSVPIALAEVHSTRADGNRALDAGDHEGALSAAASIRAMMSILGCD
PLDERWETRDETSAALNAVDVLVTAELQRRETARTEKNWALADEIRDRLKRAGLEITDTADGPQWTLTSSDEEQYHHGR

Sequences:

>Translated_479_residues
MTGHVPLRLYDTRVGAVRDFVPLQPGTVSIYLCGATVQGLPHIGHVRSGVAFDVLRRWLSARAYDVLFVRNVTDIDDKIL
NKAADAGRPWWEWAATYERAFDEAYESLGVLPPSVSPRATGHITQMIELIDRLIERGHAYRDLREGGGDVYFDVLSYPEY
GQLSGHKIDDVHQGEGVATGKRDPRDFTLWKGAKPGEPSWPTPWGPGRPGWHLECSAMARTYLGPSFDIHCGGMDLVFPH
HENEIAQSCAAGDGFARYWMHNGWVTMGGEKMSKSLGNVLSIPAVLQRVRAVELRYYLGSAHYRSMLEYSETALADAVKA
YCGIEDFLHRVRIRVGDVPVGTWTPAFAAALDDDLSVPIALAEVHSTRADGNRALDAGDHEGALSAAASIRAMMSILGCD
PLDERWETRDETSAALNAVDVLVTAELQRRETARTEKNWALADEIRDRLKRAGLEITDTADGPQWTLTSSDEEQYHHGR
>Mature_478_residues
TGHVPLRLYDTRVGAVRDFVPLQPGTVSIYLCGATVQGLPHIGHVRSGVAFDVLRRWLSARAYDVLFVRNVTDIDDKILN
KAADAGRPWWEWAATYERAFDEAYESLGVLPPSVSPRATGHITQMIELIDRLIERGHAYRDLREGGGDVYFDVLSYPEYG
QLSGHKIDDVHQGEGVATGKRDPRDFTLWKGAKPGEPSWPTPWGPGRPGWHLECSAMARTYLGPSFDIHCGGMDLVFPHH
ENEIAQSCAAGDGFARYWMHNGWVTMGGEKMSKSLGNVLSIPAVLQRVRAVELRYYLGSAHYRSMLEYSETALADAVKAY
CGIEDFLHRVRIRVGDVPVGTWTPAFAAALDDDLSVPIALAEVHSTRADGNRALDAGDHEGALSAAASIRAMMSILGCDP
LDERWETRDETSAALNAVDVLVTAELQRRETARTEKNWALADEIRDRLKRAGLEITDTADGPQWTLTSSDEEQYHHGR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=484, Percent_Identity=34.7107438016529, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI10835051, Length=259, Percent_Identity=40.1544401544402, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI21269877, Length=259, Percent_Identity=40.1544401544402, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI62240992, Length=259, Percent_Identity=40.1544401544402, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI303304987, Length=259, Percent_Identity=40.1544401544402, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI1786737, Length=463, Percent_Identity=42.3326133909287, Blast_Score=330, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17509797, Length=268, Percent_Identity=35.8208955223881, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17509795, Length=268, Percent_Identity=35.8208955223881, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=342, Percent_Identity=31.8713450292398, Blast_Score=196, Evalue=5e-51,
Organism=Drosophila melanogaster, GI19922218, Length=517, Percent_Identity=31.5280464216634, Blast_Score=231, Evalue=7e-61,
Organism=Drosophila melanogaster, GI19922364, Length=312, Percent_Identity=36.8589743589744, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53063; Mature: 52932

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGHVPLRLYDTRVGAVRDFVPLQPGTVSIYLCGATVQGLPHIGHVRSGVAFDVLRRWLS
CCCCEEEEEECCCHHHHHHCCCCCCCEEEEEEECCHHCCCCCHHHHHCCHHHHHHHHHHC
ARAYDVLFVRNVTDIDDKILNKAADAGRPWWEWAATYERAFDEAYESLGVLPPSVSPRAT
CCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
GHITQMIELIDRLIERGHAYRDLREGGGDVYFDVLSYPEYGQLSGHKIDDVHQGEGVATG
HHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
KRDPRDFTLWKGAKPGEPSWPTPWGPGRPGWHLECSAMARTYLGPSFDIHCGGMDLVFPH
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCEEEECCC
HENEIAQSCAAGDGFARYWMHNGWVTMGGEKMSKSLGNVLSIPAVLQRVRAVELRYYLGS
CHHHHHHHHHCCCCHHHHHEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AHYRSMLEYSETALADAVKAYCGIEDFLHRVRIRVGDVPVGTWTPAFAAALDDDLSVPIA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCCCCCEE
LAEVHSTRADGNRALDAGDHEGALSAAASIRAMMSILGCDPLDERWETRDETSAALNAVD
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHH
VLVTAELQRRETARTEKNWALADEIRDRLKRAGLEITDTADGPQWTLTSSDEEQYHHGR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCHHHHCCCC
>Mature Secondary Structure 
TGHVPLRLYDTRVGAVRDFVPLQPGTVSIYLCGATVQGLPHIGHVRSGVAFDVLRRWLS
CCCEEEEEECCCHHHHHHCCCCCCCEEEEEEECCHHCCCCCHHHHHCCHHHHHHHHHHC
ARAYDVLFVRNVTDIDDKILNKAADAGRPWWEWAATYERAFDEAYESLGVLPPSVSPRAT
CCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
GHITQMIELIDRLIERGHAYRDLREGGGDVYFDVLSYPEYGQLSGHKIDDVHQGEGVATG
HHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
KRDPRDFTLWKGAKPGEPSWPTPWGPGRPGWHLECSAMARTYLGPSFDIHCGGMDLVFPH
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCEEEECCC
HENEIAQSCAAGDGFARYWMHNGWVTMGGEKMSKSLGNVLSIPAVLQRVRAVELRYYLGS
CHHHHHHHHHCCCCHHHHHEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AHYRSMLEYSETALADAVKAYCGIEDFLHRVRIRVGDVPVGTWTPAFAAALDDDLSVPIA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCCCCCEE
LAEVHSTRADGNRALDAGDHEGALSAAASIRAMMSILGCDPLDERWETRDETSAALNAVD
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHH
VLVTAELQRRETARTEKNWALADEIRDRLKRAGLEITDTADGPQWTLTSSDEEQYHHGR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA