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The map label for this gene is folB [H]

Identifier: 169627640

GI number: 169627640

Start: 538201

End: 538581

Strand: Direct

Name: folB [H]

Synonym: MAB_0536

Alternate gene names: 169627640

Gene position: 538201-538581 (Clockwise)

Preceding gene: 169627639

Following gene: 169627641

Centisome position: 10.62

GC content: 64.04

Gene sequence:

>381_bases
ATGACCGACCGTATCGAGCTGCGTGGGTTGAAAGTATTTGGCTACCACGGAGTTTTTGAGCATGAGCGTCGTGATGGACA
GGAGTTTTCGGTCGACATCACTGTCTGGCTGGACCTCGATACGGCGGCGGCCACCGATCAGCTGGCCGACACACTTGACT
ACGGAGACTTGGCTCAGCGCGCGGCCGCGATCGTGTCGGGGCCGCCGCGCAATCTCATCGAGTCCGTCGCGGGTGCGATC
GCCGAGGACGTGATGACCGACTCACGAGTTCACGCGGTGGAGGCGGTGGTGCATAAGCCGAACGCGCCGATTCCGTTGAC
GTTCGGCGATGTGGCGGTGGTGGCCCGTCGCTCCCGGCGATCTCGGTCCGGGGCGCGGTAG

Upstream 100 bases:

>100_bases
CCGAGGTGACGGTGCGCACCGCACGGCCCGAGCCCAGTAAGACCGCGGGTGGCAGGTGGCGTCGGGAGGTGGCGCAACGC
GGCGCCAAAGGTGAACCGAA

Downstream 100 bases:

>100_bases
CGGTGCGTGCCGTGCTTTCGATCGGCTCCAATGTCGGTGACAGGCTCGCGCACCTGCAATCGGTGGTGGACGCACTGGGC
TCGGACGTGGTCGGCGTCTC

Product: dihydroneopterin aldolase (FolB)

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MTDRIELRGLKVFGYHGVFEHERRDGQEFSVDITVWLDLDTAAATDQLADTLDYGDLAQRAAAIVSGPPRNLIESVAGAI
AEDVMTDSRVHAVEAVVHKPNAPIPLTFGDVAVVARRSRRSRSGAR

Sequences:

>Translated_126_residues
MTDRIELRGLKVFGYHGVFEHERRDGQEFSVDITVWLDLDTAAATDQLADTLDYGDLAQRAAAIVSGPPRNLIESVAGAI
AEDVMTDSRVHAVEAVVHKPNAPIPLTFGDVAVVARRSRRSRSGAR
>Mature_125_residues
TDRIELRGLKVFGYHGVFEHERRDGQEFSVDITVWLDLDTAAATDQLADTLDYGDLAQRAAAIVSGPPRNLIESVAGAIA
EDVMTDSRVHAVEAVVHKPNAPIPLTFGDVAVVARRSRRSRSGAR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13725; Mature: 13593

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRIELRGLKVFGYHGVFEHERRDGQEFSVDITVWLDLDTAAATDQLADTLDYGDLAQR
CCCCEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHCCHHHHHHH
AAAIVSGPPRNLIESVAGAIAEDVMTDSRVHAVEAVVHKPNAPIPLTFGDVAVVARRSRR
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHH
SRSGAR
CCCCCC
>Mature Secondary Structure 
TDRIELRGLKVFGYHGVFEHERRDGQEFSVDITVWLDLDTAAATDQLADTLDYGDLAQR
CCCEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHCCHHHHHHH
AAAIVSGPPRNLIESVAGAIAEDVMTDSRVHAVEAVVHKPNAPIPLTFGDVAVVARRSRR
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHH
SRSGAR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]