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The map label for this gene is bdhA [H]

Identifier: 169627630

GI number: 169627630

Start: 526714

End: 527745

Strand: Reverse

Name: bdhA [H]

Synonym: MAB_0526c

Alternate gene names: 169627630

Gene position: 527745-526714 (Counterclockwise)

Preceding gene: 169627631

Following gene: 169627629

Centisome position: 10.41

GC content: 64.92

Gene sequence:

>1032_bases
ATGCGGGCGTCGGTGCTACGCAACGGCTCAATGGTCTATCGCGATGATGTGCCCAGCCCTACACCGGGCGAGGGACAGGT
GCTGGTCAAGGTGTCCGCTTGCGGCATCTGCGGATCCGACCTGCATTTCGCCAAACACGGGGCGCGGGCCATCGAGCTGT
CCAAACAGATGGTGGGCATGCCCAGCCTCACCGATGGCGTCGACTTAAGCACCGATGTTTTCATGGGCCACGAGTTCGCG
GCAGAAGTGATCGAGGCCGGGCCGCGGACGCAAGCACCCGCCTCCGGAACCGCGGTGACCTCAATTCCAATCCTCCTGTC
TGCCAAGGGCCTCGAACCCATCGTCTACAGCAACACCACCCTCGGCGGCTATGCCGAACAGATGCTGCTCAGTGCGCCGC
TGCTGCTGCCCATCCCCAACGGCCTCGATCCCCGGCACGCGGCCCTGACCGAACCCATGGCCGTGGGCCTGCATGCCGTT
AACAAGTCGGCCATCCAGCCGGGCACCGGAGCAATCGTCATCGGTTGTGGCCCCGTCGGTATTGCCGTGATCGCCGCCCT
GCACAACCTGGGCATCGAGCCAATCGTCGCCTCCGACTACTCCTCTGCCCGGCGCGATCTGGCCCAACGCATGGGCGCGC
ACCAGGTGGTCGACCCCAAGATCGAGCCCACCTTCCACGCCTGGTCCCGGATAGGCGCGGGTGCGCCCGTGATCTTCGAG
GCCGTTGGAGTGCCGGGCATCCTCAACGAGGTCTTGCGCGACGCGCCGCGCAGCGCACGAGTGGTGGTCGTGGGCGTCTG
CATGGAGCCCGATGCCATCACCCCCTATTTCGGGATCGCCAAGGAAGTTGCGGTGCAGTTCGTGCTCGCCTACGAGCCCG
CCGAGTTCTCCGAAACGCTGCGTCGAATCGCGCACGGTGAGATCGATGTTGCGCCGCTCGTCACAGGTGAGGTAGGTCTG
GAAGATGTCGGTTCGGCATTTGCCGATCTCGGCGATCCCGAGCGCCACTGCAAGATCTTGGTGGTGCCATGA

Upstream 100 bases:

>100_bases
ACGACTGGGCCCAGGCCAAGCGAGGCGAACTACTGGGGCGCGCGGGCGACGCGGTCGCCAAGGCTATCGGTGAGCACGTG
GCGCAGAAGGCATCGCACTG

Downstream 100 bases:

>100_bases
AGGTTGGGGAGGACAGGAAGTGACATGCGGGTACTAGCACGAAAAGCACTGACCCGGACTACCGCCATAGCCGGTGCCGC
CGCGCTGGCGGTTCTTCTCG

Product: hypothetical protein

Products: NA

Alternate protein names: Acetoin reductase/2,3-butanediol dehydrogenase; AR/BDH [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRASVLRNGSMVYRDDVPSPTPGEGQVLVKVSACGICGSDLHFAKHGARAIELSKQMVGMPSLTDGVDLSTDVFMGHEFA
AEVIEAGPRTQAPASGTAVTSIPILLSAKGLEPIVYSNTTLGGYAEQMLLSAPLLLPIPNGLDPRHAALTEPMAVGLHAV
NKSAIQPGTGAIVIGCGPVGIAVIAALHNLGIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTFHAWSRIGAGAPVIFE
AVGVPGILNEVLRDAPRSARVVVVGVCMEPDAITPYFGIAKEVAVQFVLAYEPAEFSETLRRIAHGEIDVAPLVTGEVGL
EDVGSAFADLGDPERHCKILVVP

Sequences:

>Translated_343_residues
MRASVLRNGSMVYRDDVPSPTPGEGQVLVKVSACGICGSDLHFAKHGARAIELSKQMVGMPSLTDGVDLSTDVFMGHEFA
AEVIEAGPRTQAPASGTAVTSIPILLSAKGLEPIVYSNTTLGGYAEQMLLSAPLLLPIPNGLDPRHAALTEPMAVGLHAV
NKSAIQPGTGAIVIGCGPVGIAVIAALHNLGIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTFHAWSRIGAGAPVIFE
AVGVPGILNEVLRDAPRSARVVVVGVCMEPDAITPYFGIAKEVAVQFVLAYEPAEFSETLRRIAHGEIDVAPLVTGEVGL
EDVGSAFADLGDPERHCKILVVP
>Mature_343_residues
MRASVLRNGSMVYRDDVPSPTPGEGQVLVKVSACGICGSDLHFAKHGARAIELSKQMVGMPSLTDGVDLSTDVFMGHEFA
AEVIEAGPRTQAPASGTAVTSIPILLSAKGLEPIVYSNTTLGGYAEQMLLSAPLLLPIPNGLDPRHAALTEPMAVGLHAV
NKSAIQPGTGAIVIGCGPVGIAVIAALHNLGIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTFHAWSRIGAGAPVIFE
AVGVPGILNEVLRDAPRSARVVVVGVCMEPDAITPYFGIAKEVAVQFVLAYEPAEFSETLRRIAHGEIDVAPLVTGEVGL
EDVGSAFADLGDPERHCKILVVP

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=329, Percent_Identity=23.1003039513678, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788073, Length=331, Percent_Identity=27.190332326284, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790718, Length=329, Percent_Identity=24.9240121580547, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI226510992, Length=313, Percent_Identity=27.7955271565495, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787863, Length=336, Percent_Identity=22.9166666666667, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790045, Length=341, Percent_Identity=22.8739002932551, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788407, Length=342, Percent_Identity=23.9766081871345, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788075, Length=349, Percent_Identity=23.4957020057307, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87082125, Length=226, Percent_Identity=24.7787610619469, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=331, Percent_Identity=25.0755287009063, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562878, Length=216, Percent_Identity=26.8518518518519, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=385, Percent_Identity=26.4935064935065, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319257, Length=390, Percent_Identity=24.6153846153846, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322619, Length=328, Percent_Identity=22.2560975609756, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319955, Length=328, Percent_Identity=22.2560975609756, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=330, Percent_Identity=23.9393939393939, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17137530, Length=328, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17737897, Length=328, Percent_Identity=24.390243902439, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.4 [H]

Molecular weight: Translated: 35806; Mature: 35806

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASVLRNGSMVYRDDVPSPTPGEGQVLVKVSACGICGSDLHFAKHGARAIELSKQMVGM
CCCCEECCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHCCC
PSLTDGVDLSTDVFMGHEFAAEVIEAGPRTQAPASGTAVTSIPILLSAKGLEPIVYSNTT
CCCCCCCCCCHHHHHCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCEEECCCC
LGGYAEQMLLSAPLLLPIPNGLDPRHAALTEPMAVGLHAVNKSAIQPGTGAIVIGCGPVG
CCHHHHHHHHHCCCEEECCCCCCCCHHHHCCHHHHHHHHHCHHHCCCCCCEEEEECCHHH
IAVIAALHNLGIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTFHAWSRIGAGAPVIFE
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHHH
AVGVPGILNEVLRDAPRSARVVVVGVCMEPDAITPYFGIAKEVAVQFVLAYEPAEFSETL
HCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHEEHEEECCHHHHHHH
RRIAHGEIDVAPLVTGEVGLEDVGSAFADLGDPERHCKILVVP
HHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure
MRASVLRNGSMVYRDDVPSPTPGEGQVLVKVSACGICGSDLHFAKHGARAIELSKQMVGM
CCCCEECCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHCCC
PSLTDGVDLSTDVFMGHEFAAEVIEAGPRTQAPASGTAVTSIPILLSAKGLEPIVYSNTT
CCCCCCCCCCHHHHHCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCEEECCCC
LGGYAEQMLLSAPLLLPIPNGLDPRHAALTEPMAVGLHAVNKSAIQPGTGAIVIGCGPVG
CCHHHHHHHHHCCCEEECCCCCCCCHHHHCCHHHHHHHHHCHHHCCCCCCEEEEECCHHH
IAVIAALHNLGIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTFHAWSRIGAGAPVIFE
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHHH
AVGVPGILNEVLRDAPRSARVVVVGVCMEPDAITPYFGIAKEVAVQFVLAYEPAEFSETL
HCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHEEHEEECCHHHHHHH
RRIAHGEIDVAPLVTGEVGLEDVGSAFADLGDPERHCKILVVP
HHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]