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The map label for this gene is bah [H]

Identifier: 169627246

GI number: 169627246

Start: 138368

End: 139402

Strand: Reverse

Name: bah [H]

Synonym: MAB_0141c

Alternate gene names: 169627246

Gene position: 139402-138368 (Counterclockwise)

Preceding gene: 169627247

Following gene: 169627245

Centisome position: 2.75

GC content: 63.38

Gene sequence:

>1035_bases
ATGACCGATCCCGCACACAAGCCCACATTCGGCGACACGGTCACCATCGAGACCGTCGGGAGCGATTCGGCTGTGCAACG
GTCTTCTCACGCCGTGGCACGGGCACTTCTTCGCCCCACCTTGGAACTGCTGGCGCGAATCGCCGCGCGCCATCCGACGG
CGAGAACGCACGGATTCCGCGCCGCCAATTTCATCGAGCTGGCTGCCTACCCGTTGCGGCCGAGTCGTGACACCCGGCGC
CGCATCGTCATGTTTGAACAGTTTCGTGCGGAATGGTTGTGGCATAAAGATCTTCCCGATCCGGACCAGGCGGCGCAGGG
CGCCATTCTGTACTTTCACGGCGGGGCGTTCATTCTCGGAGGTCTGCACAGCCACCGGCGCATGGCCGCACGCCTTGCCC
GCGCGTCGGGGATACCGGTACTGGTGGTGGACTATCGTCAGCTTCCGCTGGCGCATATCACCGATTCCATCACCGATGCG
GTGGATTCCTACCGCTACCTGCTGGACCGTGGGTATGCGCCTGGCAAGATCGTGTTCGCCGGCGATTCGGCTGGCGGCGG
GCTGGCCTTCAGCGCCGCCCTCGCGGCACGCGACGAGGGCCTACCGGTACCGGGGGGCATAGCGGCCATTTCACCGTGGG
CGGATCTCGATTGTTCGGCCAAGCGCGCCCATCCCAACGAGGCTCACGACGCCATGCTGTCCGGCTTCATTCTCTCGGTT
CCTGGGGAGTTGGGCATGGCTCGCGGTAACGGACTTGACCCGGCCTGGTCTGCGGTAAATCACGACTTCCACGGTATGCC
AGCGATTTTCATACAGGTCGGTTCACTTGAGGTGCTGCGAGTGGACGTGGACCTACTTGCCCGGCGGTGTGCAGAGGCAC
ACGTGCCGTGCACTGTTCAAGTCTGGAAGCACGCCATTCATGACTTCCAGCTCGGCGCCGATCTCTTGCCCGATGCCCGT
GCCGCGGTCGGCGATATGGCGCATTTCATCTATCGGATCACCGACCCCGACAATCTCAAGGCAGGTACACCGTGA

Upstream 100 bases:

>100_bases
CGTATCTACGTCCGGCCGGCTTCTTCGAAGCCCGGCGCAGCACACGGGACTTCCCTCTCGCCGACTACGTCTATGAGAAG
CATCCGGCGAAGGTGACCGC

Downstream 100 bases:

>100_bases
GCACGCATACCCTCCCGCAGCACGAGGTCCTCGTGGTAGGCGCCGGATTCGGCGGCATAGCCGCAGGCGTCAGACTCCGC
CGGGCAGGTATCGATGATTT

Product: putative esterase

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTDPAHKPTFGDTVTIETVGSDSAVQRSSHAVARALLRPTLELLARIAARHPTARTHGFRAANFIELAAYPLRPSRDTRR
RIVMFEQFRAEWLWHKDLPDPDQAAQGAILYFHGGAFILGGLHSHRRMAARLARASGIPVLVVDYRQLPLAHITDSITDA
VDSYRYLLDRGYAPGKIVFAGDSAGGGLAFSAALAARDEGLPVPGGIAAISPWADLDCSAKRAHPNEAHDAMLSGFILSV
PGELGMARGNGLDPAWSAVNHDFHGMPAIFIQVGSLEVLRVDVDLLARRCAEAHVPCTVQVWKHAIHDFQLGADLLPDAR
AAVGDMAHFIYRITDPDNLKAGTP

Sequences:

>Translated_344_residues
MTDPAHKPTFGDTVTIETVGSDSAVQRSSHAVARALLRPTLELLARIAARHPTARTHGFRAANFIELAAYPLRPSRDTRR
RIVMFEQFRAEWLWHKDLPDPDQAAQGAILYFHGGAFILGGLHSHRRMAARLARASGIPVLVVDYRQLPLAHITDSITDA
VDSYRYLLDRGYAPGKIVFAGDSAGGGLAFSAALAARDEGLPVPGGIAAISPWADLDCSAKRAHPNEAHDAMLSGFILSV
PGELGMARGNGLDPAWSAVNHDFHGMPAIFIQVGSLEVLRVDVDLLARRCAEAHVPCTVQVWKHAIHDFQLGADLLPDAR
AAVGDMAHFIYRITDPDNLKAGTP
>Mature_343_residues
TDPAHKPTFGDTVTIETVGSDSAVQRSSHAVARALLRPTLELLARIAARHPTARTHGFRAANFIELAAYPLRPSRDTRRR
IVMFEQFRAEWLWHKDLPDPDQAAQGAILYFHGGAFILGGLHSHRRMAARLARASGIPVLVVDYRQLPLAHITDSITDAV
DSYRYLLDRGYAPGKIVFAGDSAGGGLAFSAALAARDEGLPVPGGIAAISPWADLDCSAKRAHPNEAHDAMLSGFILSVP
GELGMARGNGLDPAWSAVNHDFHGMPAIFIQVGSLEVLRVDVDLLARRCAEAHVPCTVQVWKHAIHDFQLGADLLPDARA
AVGDMAHFIYRITDPDNLKAGTP

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786682, Length=240, Percent_Identity=28.3333333333333, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 37211; Mature: 37080

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS01174 LIPASE_GDXG_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPAHKPTFGDTVTIETVGSDSAVQRSSHAVARALLRPTLELLARIAARHPTARTHGFR
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
AANFIELAAYPLRPSRDTRRRIVMFEQFRAEWLWHKDLPDPDQAAQGAILYFHGGAFILG
HHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCEEEEC
GLHSHRRMAARLARASGIPVLVVDYRQLPLAHITDSITDAVDSYRYLLDRGYAPGKIVFA
CHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GDSAGGGLAFSAALAARDEGLPVPGGIAAISPWADLDCSAKRAHPNEAHDAMLSGFILSV
CCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEC
PGELGMARGNGLDPAWSAVNHDFHGMPAIFIQVGSLEVLRVDVDLLARRCAEAHVPCTVQ
CCHHCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCEEEEEECHHHHHHHHHHCCCCCHHH
VWKHAIHDFQLGADLLPDARAAVGDMAHFIYRITDPDNLKAGTP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCC
>Mature Secondary Structure 
TDPAHKPTFGDTVTIETVGSDSAVQRSSHAVARALLRPTLELLARIAARHPTARTHGFR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
AANFIELAAYPLRPSRDTRRRIVMFEQFRAEWLWHKDLPDPDQAAQGAILYFHGGAFILG
HHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCEEEEC
GLHSHRRMAARLARASGIPVLVVDYRQLPLAHITDSITDAVDSYRYLLDRGYAPGKIVFA
CHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GDSAGGGLAFSAALAARDEGLPVPGGIAAISPWADLDCSAKRAHPNEAHDAMLSGFILSV
CCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEC
PGELGMARGNGLDPAWSAVNHDFHGMPAIFIQVGSLEVLRVDVDLLARRCAEAHVPCTVQ
CCHHCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCEEEEEECHHHHHHHHHHCCCCCHHH
VWKHAIHDFQLGADLLPDARAAVGDMAHFIYRITDPDNLKAGTP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]