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The map label for this gene is narL [H]

Identifier: 169627165

GI number: 169627165

Start: 57232

End: 57879

Strand: Direct

Name: narL [H]

Synonym: MAB_0060

Alternate gene names: 169627165

Gene position: 57232-57879 (Clockwise)

Preceding gene: 169627162

Following gene: 169627166

Centisome position: 1.13

GC content: 68.52

Gene sequence:

>648_bases
ATGCAGGTGAGCGGCGAACTTGTGCGGGTCGTCGTCGGGGACGATCACCCCCTCTTCCGGGAGGGCGTGGTGCGGGCGCT
CACGGCCAGCGGGCAGATCACCGTGGTCGCGGAGGCTGAGAACGGCACCGGCGCGCTGGAACTGATCAGGGAGCACCGGC
CCGATGTCGCGTTGGTGGACTACCGAATGCCGGAGTTGGACGGCACCCAGGTGGCAGCCGCGGTACGCCGTGACGAACTA
CCCACCAGGGTGCTGCTGCTCTCGGCACACGACGACGCGGCCATTGTGTATCGCGCATTGGAGGAAGGGGCGGCCGGATT
TCTGTCGAAGGAATCCACTCGGACTGAGCTGGTCGGCGCCGTGCTCGACTGCGCGCGGGGACGCGACGTGGTGGCGGCAA
GCCTGACGGCGGGGCTGGCCGGCGAGATCCGCAAGCGGGCACAACCGGCGGGGCCCTCACTGAGTACCCGCGAACGTGAG
GTGCTCAGGATGATTGCCGCCGGGCAGACGGTGCCGGCGATTGCCAGGGCGCTGTTTCTGGCTCCCTCCACGGTGAAGAC
TCATGTGCAGCGCCTGTACGAGAAGCTCGGTGTCGGCGACCGTGCCGCGGCGGTGGCAGAAGCGATGCGCCGCGGCTTGC
TGGAATAG

Upstream 100 bases:

>100_bases
AAGCCGGAAAGTCTGTCGGGCGACCGACGGATGCACCGGGGGATCTTGATGTCCCCCAATCGGGGGACAGGCGTGGATTT
AGCGTGTCAAGCTTGCGTTT

Downstream 100 bases:

>100_bases
CTGCGATGACCCGGCTGGATAACATGGCCGACTATTTCGCCGCTGAACCCATGCGGGTGTCGGCCTGGCTGCGGCTGCCG
CTTATCGGGTTGATAGTGCT

Product: nitrate/nitrite response transcriptional regulatory protein NarL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MQVSGELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTGALELIREHRPDVALVDYRMPELDGTQVAAAVRRDEL
PTRVLLLSAHDDAAIVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIRKRAQPAGPSLSTRERE
VLRMIAAGQTVPAIARALFLAPSTVKTHVQRLYEKLGVGDRAAAVAEAMRRGLLE

Sequences:

>Translated_215_residues
MQVSGELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTGALELIREHRPDVALVDYRMPELDGTQVAAAVRRDEL
PTRVLLLSAHDDAAIVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIRKRAQPAGPSLSTRERE
VLRMIAAGQTVPAIARALFLAPSTVKTHVQRLYEKLGVGDRAAAVAEAMRRGLLE
>Mature_215_residues
MQVSGELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTGALELIREHRPDVALVDYRMPELDGTQVAAAVRRDEL
PTRVLLLSAHDDAAIVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIRKRAQPAGPSLSTRERE
VLRMIAAGQTVPAIARALFLAPSTVKTHVQRLYEKLGVGDRAAAVAEAMRRGLLE

Specific function: Probable member of the two-component regulatory system NarS/NarL [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=30.622009569378, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788521, Length=197, Percent_Identity=32.994923857868, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=36.0655737704918, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=34.6938775510204, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788712, Length=189, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786747, Length=189, Percent_Identity=24.3386243386243, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=25.7281553398058, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22908; Mature: 22908

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSGELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTGALELIREHRPDVALVD
CCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEE
YRMPELDGTQVAAAVRRDELPTRVLLLSAHDDAAIVYRALEEGAAGFLSKESTRTELVGA
CCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VLDCARGRDVVAASLTAGLAGEIRKRAQPAGPSLSTREREVLRMIAAGQTVPAIARALFL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHC
APSTVKTHVQRLYEKLGVGDRAAAVAEAMRRGLLE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQVSGELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTGALELIREHRPDVALVD
CCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEE
YRMPELDGTQVAAAVRRDELPTRVLLLSAHDDAAIVYRALEEGAAGFLSKESTRTELVGA
CCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VLDCARGRDVVAASLTAGLAGEIRKRAQPAGPSLSTREREVLRMIAAGQTVPAIARALFL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHC
APSTVKTHVQRLYEKLGVGDRAAAVAEAMRRGLLE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]