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The map label for this gene is ykoE [H]

Identifier: 169834143

GI number: 169834143

Start: 753137

End: 753697

Strand: Direct

Name: ykoE [H]

Synonym: SPH_0806

Alternate gene names: 169834143

Gene position: 753137-753697 (Clockwise)

Preceding gene: 169833352

Following gene: 169832436

Centisome position: 33.54

GC content: 41.53

Gene sequence:

>561_bases
ATGTTGAAAAAATGGCAGTTAAAAGATGTTATCTTGCTTGCTTTCTTGTCTATCTTTTTTGGTGGGGTTTTCGTTGGTTC
AGGATATGTGTATAATATTCTCAGTCTACTCTTAACACCTCTTGGTTTGCAGGCCTTTGCCAATGAAATCCTCTTCGGTC
TCTGGTGTATGGCTGCGCCCATTGCTGCCATCTTTGTTCCGAGAGTCGGAAGTGCAACGATTGGAGAAGTGCTAGCTGCG
CTTGCTGAAGTCCTTTATGGTAGCCAATTTGGTCTAGGAGCTCTTTTGTCTGGCTTGGTTCAAGGTTTGGGAAGTGAATT
TGGTTTTATCGTAACTAAGAATCGCTATGAAAGTTGGCTCTCTCTAACTGCTAATAGTATTGGGATTACGCTTGTTAGCT
TTGTCTATGAATACATTAAGTTAGGCTACTACGCCTTTTCCCTTCCGTTTGTCCTTTCCTTGCTTGTGGTACGTTTTATT
TCTGTTTATTTCTTCTGTACCATCTTGGTTCGTGCCATTGTCAAACTCTATCATCAGTTTGCAACTGGAGGAAAAGCATA
G

Upstream 100 bases:

>100_bases
TTAGTGTTCTTGTGTACTGTTCTAAATTCAGTCTGCTATACAAAGTATTTAGGTCTGTCTTCTTGAGTGCCCCACTTTTC
TTTAAAAAAAGGAGTTTTTT

Downstream 100 bases:

>100_bases
ATGGGTCTGGAACTACGAGCGATTCAGTCCCCAATCTTCTCTGAGCCGTTTGATTTTACTTTTCATGCGCAAGCCTTTAC
CTTGTTAGTTGGGAGCAATG

Product: ABC-type cobalt transport system, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQAFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAA
LAEVLYGSQFGLGALLSGLVQGLGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
SVYFFCTILVRAIVKLYHQFATGGKA

Sequences:

>Translated_186_residues
MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQAFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAA
LAEVLYGSQFGLGALLSGLVQGLGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
SVYFFCTILVRAIVKLYHQFATGGKA
>Mature_186_residues
MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQAFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAA
LAEVLYGSQFGLGALLSGLVQGLGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
SVYFFCTILVRAIVKLYHQFATGGKA

Specific function: Part of the ABC transporter complex ykoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)

COG id: COG4721

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017195 [H]

Pfam domain/function: PF09819 ABC_cobalt [H]

EC number: NA

Molecular weight: Translated: 20309; Mature: 20309

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQAFANEILFGLWCMAAP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQGLGSEFGFIVTKNRYESWL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHH
SLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFISVYFFCTILVRAIVKLYHQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGGKA
HCCCCC
>Mature Secondary Structure
MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQAFANEILFGLWCMAAP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQGLGSEFGFIVTKNRYESWL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHH
SLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFISVYFFCTILVRAIVKLYHQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGGKA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]