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The map label for this gene is glcK [H]

Identifier: 169834049

GI number: 169834049

Start: 718835

End: 719794

Strand: Direct

Name: glcK [H]

Synonym: SPH_0763

Alternate gene names: 169834049

Gene position: 718835-719794 (Clockwise)

Preceding gene: 169832510

Following gene: 169833725

Centisome position: 32.01

GC content: 44.38

Gene sequence:

>960_bases
ATGAGTCAAAAGATTATTGGGATTGACCTTGGTGGAACTTCTATCAAATTTGCAATCTTAACAACAGCAGGAGAAATCCA
AGGAAAATGGTCAATCAAGACCAACATTTTGGATGAGGGAAGTCATATCGTTGATGATATGATTGAGTCTATTCAACATC
GTTTGGACTTGCTTGGATTGGTGGCAGCGGATTTCCAAGGTATTGGAATGGGGTCACCAGGTGTGGTTGACCGTGAAAAC
GGGACTGTTATTGGTGCCTACAATTTGAACTGGAAAACCCTTCAACCAATTAAAGAAAAGATTGAAAAAGACTTGGGCAT
TCCATTCTTCATCGATAATGATGCCAACGTGGCTGCTCTCGGTGAGCGCTGGATGGGTGCTGGTGATAACCAACCAGACG
TTGTCTTTATGACACTTGGTACAGGTGTTGGTGGCGGTATCGTCGCAGAAGGCAAATTGCTTCACGGTGTGGCTGGTGCA
GCAGGCGAGCTTGGCCACATCACTGTTGACTTTGACCAACCAATCGCATGTACCTGTGGTAAAAAAGGCTGTCTTGAGAC
AGTTGCTTCAGCAACAGGGATTGTCAACTTGACTCGTCGCTATGCGGATGAATACGAAGGCGATGCAGCCTTGAAACGCT
TGATTGATAATGGAGAAGAAGTAACTGCTAAGACTGTCTTTGATCTCGCAAAAGAAGGAGACGACCTTGCTTTGATTGTT
TACCGTAACTTCTCACGTTACTTGGGAATCGCTTGTGCTAACATTGGTTCAATCCTAAACCCATCAACAATCGTCATCGG
TGGTGGTGTGTCAGCTGCGGGAGAATTCCTTCTACAAGGTGTTCAAAAAGTCTATGATGAAAATACTTTCCCACAAGTAC
GCACATCTACTAAATTAGCTCTTGCAACTCTAGGAAATGACGCTGGAGTTATCGGAGCAGCATCACTTGTATTGCAATAA

Upstream 100 bases:

>100_bases
TTATAATTCACTTACGCAAACCTTTGCATAAGTGAATGGATTTTGATATACTAGTACTGTAAGCATTTTCAATTACTACA
CAATGAAAAAGGAGAATATG

Downstream 100 bases:

>100_bases
GATAATGAGAGAGGAAAAATGCTAACCTAGAGTTAGTAATGTTCCTCTTTTATTTTTTATGCTATACTAGTTAGGACAAT
GAATGAGGTGAGAGTAAATG

Product: glucokinase (glucose kinase)

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLVAADFQGIGMGSPGVVDREN
GTVIGAYNLNWKTLQPIKEKIEKDLGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ

Sequences:

>Translated_319_residues
MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLVAADFQGIGMGSPGVVDREN
GTVIGAYNLNWKTLQPIKEKIEKDLGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ
>Mature_318_residues
SQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLVAADFQGIGMGSPGVVDRENG
TVIGAYNLNWKTLQPIKEKIEKDLGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGAA
GELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIVY
RNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=275, Percent_Identity=30.5454545454545, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI298566315, Length=275, Percent_Identity=30.5454545454545, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4885285, Length=275, Percent_Identity=30.5454545454545, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI190014632, Length=275, Percent_Identity=30.5454545454545, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI87081733, Length=322, Percent_Identity=30.1242236024845, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787363, Length=321, Percent_Identity=27.4143302180685, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786891, Length=283, Percent_Identity=27.9151943462898, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787878, Length=250, Percent_Identity=26.8, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082230, Length=273, Percent_Identity=30.03663003663, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790522, Length=323, Percent_Identity=27.2445820433437, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082127, Length=258, Percent_Identity=24.4186046511628, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33495; Mature: 33363

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGL
CCCEEEEEEECCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VAADFQGIGMGSPGVVDRENGTVIGAYNLNWKTLQPIKEKIEKDLGIPFFIDNDANVAAL
HHHCCCCCCCCCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCEEEH
GERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGAAGELGHITVDFDQPIACTCG
HHHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEECCCCEEEECC
KKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENTFPQVRTSTKLA
EECCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LATLGNDAGVIGAASLVLQ
EEECCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGL
CCEEEEEEECCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VAADFQGIGMGSPGVVDRENGTVIGAYNLNWKTLQPIKEKIEKDLGIPFFIDNDANVAAL
HHHCCCCCCCCCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCEEEH
GERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGAAGELGHITVDFDQPIACTCG
HHHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEECCCCEEEECC
KKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENTFPQVRTSTKLA
EECCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LATLGNDAGVIGAASLVLQ
EEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]