Click here to switch to the map view.

The map label for this gene is msmR [H]

Identifier: 169833559

GI number: 169833559

Start: 1876203

End: 1877063

Strand: Direct

Name: msmR [H]

Synonym: SPH_2016

Alternate gene names: 169833559

Gene position: 1876203-1877063 (Clockwise)

Preceding gene: 169833147

Following gene: 169832935

Centisome position: 83.55

GC content: 36.59

Gene sequence:

>861_bases
ATGTTAGTTTTTTCAGAATACCAGACTGGAACAATCGACCTTGCCCTAAGCTTTTATGGATATGAGGAATGCACACCTAA
TTACTCTTTTGGTCCAGCCATTCGTGATACATACGTCCTACATTACATTACTAAAGGACAAGGAAAATTTCATTACAAGG
GTAAAATTGTTGATTTAAAAGAAGGAGATTTCTTTCTATTAAAACCAGAGGAACTAACCTTTTATCAAGCAGATAGTAAA
GAACCTTGGGCCTACTACTGGTTAGGAATCACTGGAGGGAAATCCCCTGATTATTTTGCTCTTTCTCAAATTTCTGATCA
ATCCTATCTCATCCAATCTGAAACTTGTCATACCCAGACTACTGCAAAACTCATCTCAGACATTGTCCGCTTCGCTCAGA
TTACAAAATCAAGTGAATTAGCTCAACTCCATATCATGGGACAACTTCATGAACTGATGTTTCATCTGGGAACTATTGCT
CCCAATCAGAAAAAAAAGAATATTTCATCAACCCACCAACTCTATCTTGAATGCAAACGATTAATTGATAGCCACTATCC
TCAATCACTTACAATTCAAGATTTAGCAAAAGAACTATCCGTTCACAGAAGCTACTTATCAAGCGTATTCAAAGAATTTA
ATACCTTATCACCCAAAGAATACCTACTCTACGTTCGAATGCACCGAGCTAGACAACTTCTCGAAAATACCCAAGAGTCC
ATCAAGGTAATTGCATACTCGGTAGGTTTTTCAGATCCACTCCATTTTTCGAAAGCTTATAAACAATACTTTAATCAGAC
TCCAAGTCATACAAGAAAAGAATACTCTCAATACCAACTAGTAAGAAAGGCAACATTATGA

Upstream 100 bases:

>100_bases
ACCTCATCACTTTATTGATTATATTTTATCACCTGAAATCGCTTTCTAAAATAGAAAAATGTCTCAAGAATATGGTAAAA
TGTTAGGTAGGAGGTAGCAC

Downstream 100 bases:

>100_bases
AATCCTACCAAGCTGTCTACCAAATCCTATCTAAAGAAACCGACTATATCAGCGGAGAAAAAATCGCAGAAAAACTATCC
CTAAGCCGAACATCAATTTG

Product: msm operon regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYITKGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSK
EPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
IKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYSQYQLVRKATL

Sequences:

>Translated_286_residues
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYITKGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSK
EPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
IKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYSQYQLVRKATL
>Mature_286_residues
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYITKGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSK
EPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
IKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYSQYQLVRKATL

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI226510985, Length=252, Percent_Identity=24.6031746031746, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33219; Mature: 33219

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYITKGQGKFHYKGKIVDLK
CEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHEEEEEEECCCCEEEECCEEEEEC
EGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQT
CCCEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCEEEECCCCCHHH
TAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIAPNQKKKNISSTHQLYLECKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHH
LIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYSQYQLVRKATL
HEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYITKGQGKFHYKGKIVDLK
CEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHEEEEEEECCCCEEEECCEEEEEC
EGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQT
CCCEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCEEEECCCCCHHH
TAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIAPNQKKKNISSTHQLYLECKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHH
LIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYSQYQLVRKATL
HEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]