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The map label for this gene is dexB [H]

Identifier: 169833166

GI number: 169833166

Start: 401892

End: 403499

Strand: Direct

Name: dexB [H]

Synonym: SPH_0452

Alternate gene names: 169833166

Gene position: 401892-403499 (Clockwise)

Preceding gene: 169833795

Following gene: 169833491

Centisome position: 17.9

GC content: 42.72

Gene sequence:

>1608_bases
ATGCAAGAAAAATGGTGGCATAATGCCGTAGTCTATCAAGTCTATCCAAAGAGTTTTATGGATAGTAATGGAGATGGAGT
TGGTGATTTGCCAGGTATTACCAGTAAGTTGGACTATCTAGCTAAGCTAGGAATCACAGCGATTTGGCTTTCTCCCGTTT
ATGACAGCCCTATGGATGATAATGGCTACGATATTGCTGATTATCAAGCGATTGCAACGATTTTTGGAACCATGGAGGAT
ATGGATCAGCTGATTGCAGAAGCTAAGAAGCGTGACATTCGTATCATCATGGACTTGGTGGTTAATCATACCTCAGATGA
ACATGCTTGGTTTGTCGAAGCCTGTGAAAATACTGATAGCCCTGAGCGAGACTACTATATCTGGCGGGATGAGCCTAACG
ATTTAGATTCTATCTTTAGTGGGTCTGCTTGGGAATACGATGAAAAGTCAGGTCAATACTATCTCCACTTTTTCAGCAAG
AAACAGCCGGATCTCAACTGGAAAAATGAAAAACTTCGCCAGAAAATTTATGAGATGATGAACTTCTGGATTGATAAAGG
TATTGGTGGTTTCCGTATGGATGTTATTGACATGATTGGCAAAATTCCTGACGAGAAGGTAGTCAATAATGGTCCTATGC
TCCATCCCTATCTCAAGGAAATGAATCAGGCGACCTTTGGAGATAAGGATCTCTTGACAGTAGGGGAGACTTGGGGAGCA
ACGCCAGAGATTGCCAAGCTCTACTCTGATCCAAAGGGGCAAGAATTGTCTATGGTCTTCCAGTTTGAACATATCGGTCT
TCAGTATCAGGAAGGTCAGCCTAAATGGCACTATCAAAAAGAGCTGAATATCGCTAAGTTAAAAGAAATCTTCAACAAAT
GGCAGACAGAGTTAGGAGTTGAGGACGGCTGGAATTCCCTCTTCTGGAACAACCATGACCTCCCACGTATTGTCTCAATC
TGGGGAAATGACCAAGAATACCGCGAAAAATCTGCCAAAGCCTTTGCAATCTTGCTTCATCTCATGAGAGGAACTCCTTA
TATCTACCAAGGTGAGGAGATTGGGATGACCAACTATCCGTTTGAAACACTGGATCAAGTAGAAGATATTGAATCTCTCA
ACTATGCGCGTGAGGCTCTTGAAAAAGGTGTTCCGATTGAAGAAATCATGGACAGTATCCGTGTTATTGGACGTGACAAT
GCCCGTACCCCTATGCAATGGGACGAGAGCAAAAACGCTGGTTTCTCAACAGGTCAACCTTGGTTGGCGGTTAATCCAAA
TTACGAGATGATCAATGTCCAAGAAGCGCTGGCAAATCCAGATTCTATTTTCTATACCTATCAGAAACTGGTCCAAATTC
GCAAGGAGAATAGCTGGCTAGTTCGAGCTGACTTTGAATTGCTTGATACGGCTGATAAGGTCTTTGCTTATATACGTAAG
GATGGCGACCGTCGCTTCCTAGTTGTGGCTAACTTGTCCAATGAAGAGCAAGACTTGACAGTAGAAGGAAAAGTCAAATC
TGTCTTGATTGAAAACACTGCGGCTAAAGAAGTACTTGAAAAACAGGTCTTGGCTCCATGGGATGCTTTCTGTGTGGAAT
TACTATAA

Upstream 100 bases:

>100_bases
GGAGCTAAAAAAGAAATTAAAAAGATTAAGCAAACGCTTGCACAAAATTTTAAAAAGTGCTATCATAGACTATAGATTAT
GAAAATAATGAGGTAAACAG

Downstream 100 bases:

>100_bases
ATATTTTTTGCAGAAAAATTTAAAATTGAAATCATATAAAAACAAGGGAGGACTGTATAAAAGACAGAAATCCTTTGTTT
TTTATAACCAAGGTTTATAA

Product: trehalose-6-phosphate hydrolase (Alpha,alpha-phosphotrehalase)

Products: NA

Alternate protein names: Dextran glucosidase; Exo-1,6-alpha-glucosidase; Glucodextranase [H]

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLGITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMED
MDQLIAEAKKRDIRIIMDLVVNHTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
KQPDLNWKNEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYLKEMNQATFGDKDLLTVGETWGA
TPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKWHYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSI
WGNDQEYREKSAKAFAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDSIRVIGRDN
ARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKLVQIRKENSWLVRADFELLDTADKVFAYIRK
DGDRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL

Sequences:

>Translated_535_residues
MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLGITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMED
MDQLIAEAKKRDIRIIMDLVVNHTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
KQPDLNWKNEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYLKEMNQATFGDKDLLTVGETWGA
TPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKWHYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSI
WGNDQEYREKSAKAFAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDSIRVIGRDN
ARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKLVQIRKENSWLVRADFELLDTADKVFAYIRK
DGDRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL
>Mature_535_residues
MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLGITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMED
MDQLIAEAKKRDIRIIMDLVVNHTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
KQPDLNWKNEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYLKEMNQATFGDKDLLTVGETWGA
TPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKWHYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSI
WGNDQEYREKSAKAFAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDSIRVIGRDN
ARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKLVQIRKENSWLVRADFELLDTADKVFAYIRK
DGDRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL

Specific function: The physiological substrates may be short isomaltosaccharides [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=520, Percent_Identity=29.8076923076923, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI61744483, Length=122, Percent_Identity=32.7868852459016, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI61744481, Length=122, Percent_Identity=32.7868852459016, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI61744479, Length=122, Percent_Identity=32.7868852459016, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI65506891, Length=122, Percent_Identity=32.7868852459016, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI61744477, Length=122, Percent_Identity=32.7868852459016, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI61744475, Length=122, Percent_Identity=32.7868852459016, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1790687, Length=509, Percent_Identity=46.3654223968566, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1786604, Length=187, Percent_Identity=32.0855614973262, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI25147709, Length=497, Percent_Identity=25.7545271629779, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32565753, Length=199, Percent_Identity=32.6633165829146, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=36.6782006920415, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6321726, Length=581, Percent_Identity=36.3166953528399, Blast_Score=357, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6322241, Length=579, Percent_Identity=36.0967184801382, Blast_Score=345, Evalue=7e-96,
Organism=Saccharomyces cerevisiae, GI6322021, Length=579, Percent_Identity=36.0967184801382, Blast_Score=345, Evalue=7e-96,
Organism=Saccharomyces cerevisiae, GI6324416, Length=579, Percent_Identity=36.0967184801382, Blast_Score=345, Evalue=8e-96,
Organism=Saccharomyces cerevisiae, GI6319776, Length=576, Percent_Identity=34.0277777777778, Blast_Score=322, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6321731, Length=576, Percent_Identity=33.8541666666667, Blast_Score=320, Evalue=2e-88,
Organism=Drosophila melanogaster, GI221330053, Length=534, Percent_Identity=34.4569288389513, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24586593, Length=533, Percent_Identity=33.7711069418386, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24583745, Length=590, Percent_Identity=32.8813559322034, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24583747, Length=535, Percent_Identity=33.6448598130841, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI24583749, Length=535, Percent_Identity=33.6448598130841, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI24586597, Length=535, Percent_Identity=31.9626168224299, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24586589, Length=549, Percent_Identity=31.3296903460838, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24586587, Length=539, Percent_Identity=32.2820037105751, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24586591, Length=551, Percent_Identity=32.486388384755, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24586599, Length=520, Percent_Identity=32.1153846153846, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI45549022, Length=546, Percent_Identity=32.2344322344322, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI281360393, Length=479, Percent_Identity=30.062630480167, Blast_Score=200, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.70 [H]

Molecular weight: Translated: 62031; Mature: 62031

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLGITAIWLSPVYDSPMDD
CCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCC
NGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVNHTSDEHAWFVEACENTDS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEHHHHCCCCC
PERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSKKQPDLNWKNEKLRQKIYEMM
CCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
NFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYLKEMNQATFGDKDLLTVGETWGA
HHHHHCCCCCHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCC
TPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKWHYQKELNIAKLKEIFNKWQTELGV
CHHHHHHHCCCCCCEEEEEEEEECCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHCCC
EDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKAFAILLHLMRGTPYIYQGEEIGMTNYP
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
FETLDQVEDIESLNYAREALEKGVPIEEIMDSIRVIGRDNARTPMQWDESKNAGFSTGQP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
WLAVNPNYEMINVQEALANPDSIFYTYQKLVQIRKENSWLVRADFELLDTADKVFAYIRK
EEEECCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHC
DGDRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL
CCCEEEEEEEECCCCCCCEEEECCCHHHEECCHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLGITAIWLSPVYDSPMDD
CCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCC
NGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVNHTSDEHAWFVEACENTDS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEHHHHCCCCC
PERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSKKQPDLNWKNEKLRQKIYEMM
CCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
NFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYLKEMNQATFGDKDLLTVGETWGA
HHHHHCCCCCHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCC
TPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKWHYQKELNIAKLKEIFNKWQTELGV
CHHHHHHHCCCCCCEEEEEEEEECCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHCCC
EDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKAFAILLHLMRGTPYIYQGEEIGMTNYP
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
FETLDQVEDIESLNYAREALEKGVPIEEIMDSIRVIGRDNARTPMQWDESKNAGFSTGQP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
WLAVNPNYEMINVQEALANPDSIFYTYQKLVQIRKENSWLVRADFELLDTADKVFAYIRK
EEEECCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHC
DGDRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL
CCCEEEEEEEECCCCCCCEEEECCCHHHEECCHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11463916; 8566758; 8021229; 9466257; 9383201 [H]