Click here to switch to the map view.

The map label for this gene is lytR [H]

Identifier: 169833033

GI number: 169833033

Start: 404901

End: 406346

Strand: Direct

Name: lytR [H]

Synonym: SPH_0455

Alternate gene names: 169833033

Gene position: 404901-406346 (Clockwise)

Preceding gene: 169833491

Following gene: 169832438

Centisome position: 18.03

GC content: 38.93

Gene sequence:

>1446_bases
ATGAGTAGACGTTTTAAAAAATCAGGTTCACAGAAAGTGAAGCGAAGTGTTAATATCGTTTTGCTGACTATTTATTTATT
GTTAGTTTGTTTTTTATTGTTCTTAATCTTTAAGTACAATATCCTTGCTTTTAGATATCTTAACCTAGTGGTAACTGCGT
TAGTCCTACTAGTTGCCTTGGTAGGGCTACTCTTGATTATCTATAAAAAAGCTGAAAAGTTTACTATTTTTCTGTTGCTG
TTCTCTATCCTTGTCAGCTCTGTGTCGCTCTTTGCAGTACAGCAGTTTGTTGGACTGACCAATCGTTTAAATGCGGCTTC
GAATTACTCAGAATATTCGATCAGTGTCGCTGTTTTAGCAGATAGTGAGATCGAAAATGTTACGCAACTGACGAGTGTGA
CAGCACCGACTGGGACTGATAATGAAAATATTCAAAAACTACTAGCTGATATCAAGTCAAGTCAGAATACCGATTTGACG
GTCAACCAGAGTTCGTCTTACTTGGCAGCTTACAAGAGTTTGATTGCAGGGGAGACTAAGGCCATTGTCCTAAATAGTGT
CTTTGAAAATATCATCGAGTCAGAGTATCCAGACTACGCATCGAAGATAAAGAAGATTTATACCAAGGGATTCACTAAAA
AAGTAGAAGCTCCTAAGACGTCTAAGAATCAGTCTTTCAATATCTATGTTAGTGGAATTGACACCTATGGTCCTATTAGT
TCGGTGTCGCGATCAGATGTCAATATCCTGATGACTGTCAATCGAGATACCAAGAAAATCCTCTTGACCACAACGCCACG
TGATGCCTATGTACCAATCGCAGATGGTGGAAATAATCAAAAAGATAAATTAACCCATGCGGGCATTTATGGAGTTGATT
CGTCCATTCACACCTTAGAAAATCTCTATGGAGTGGATATCAATTACTATGTGCGATTGAACTTCACTTCTTTCTTGAAA
TTGATTGACTTATTGGGAGGGGTAGATGTTCATAATGATCAAGAGTTTTCAGCTCTACATGGGAAGTTCCATTTCCCAGT
AGGGAATGTCCATCTAGACTCTGAGCAAGCTCTAGGTTTTGTACGTGAACGCTACTCACTAGCCGATGGAGACCGTGACC
GTGGTCGCAACCAACAAAAGGTGATTGTGGCTATCCTTCAAAAATTAACGTCAACCGAAGCACTGAAAAATTATGGTACG
ATCATTAATAGCTTGCAAGATTCTATCCAAACAAATATGCCACTTGAGACCATGATAAATTTGGTCAATGCTCAGTTAGA
AAGTGGAGGGAATTATAAAGTAAATTCTCAAGATTTAAAAGGGACAGGTCGGATGGATCTTCCTTCTTATGCAATGCCAG
ACAGTAACCTCTATGTGCTGGAAATAGATGATAGTAGTTTAGCTGTAGTTAAAGCAGCTATACAGGATGTGATGGAGGGT
AGATGA

Upstream 100 bases:

>100_bases
GTCTACTAAGATACTTAAAGATGCAGATAGTAAAAAAAATGTAGACATTACCGTAAAAAAGTGATATAATCGTATGATGT
TCAAGGTATAGGTGTTAATC

Downstream 100 bases:

>100_bases
AATGATAGACATCCATTCGCATATCGTTTTTGATGTAGATGACGGTCCCAAGTCAAGAGAGGAAAGCAAGGCTCTCTTGG
CAGAATCCTATAGGCAGGGG

Product: integral membrane regulatory protein Wzg

Products: NA

Alternate protein names: Membrane-bound protein lytR [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLL
FSILVSSVSLFAVQQFVGLTNRLNAASNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAPKTSKNQSFNIYVSGIDTYGPIS
SVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLK
LIDLLGGVDVHNDQEFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTSTEALKNYGT
IINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSYAMPDSNLYVLEIDDSSLAVVKAAIQDVMEG
R

Sequences:

>Translated_481_residues
MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLL
FSILVSSVSLFAVQQFVGLTNRLNAASNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAPKTSKNQSFNIYVSGIDTYGPIS
SVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLK
LIDLLGGVDVHNDQEFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTSTEALKNYGT
IINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSYAMPDSNLYVLEIDDSSLAVVKAAIQDVMEG
R
>Mature_480_residues
SRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLF
SILVSSVSLFAVQQFVGLTNRLNAASNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLTV
NQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAPKTSKNQSFNIYVSGIDTYGPISS
VSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKL
IDLLGGVDVHNDQEFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTSTEALKNYGTI
INSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSYAMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR

Specific function: Attenuator role for operon expression [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 53339; Mature: 53208

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFRYLNLVVTALVLLVAL
CCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNRLNAASNYSEYSISVAVLA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEE
DSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLTVNQSSSYLAAYKSLIAGETK
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCH
AIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAPKTSKNQSFNIYVSGIDTYGPIS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCEEEEEECCCCCCCHH
SVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKLTHAGIYGVDSSIHTLE
CCCCCCCEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCHHHHHCCCEECCCCHHHHHH
NLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQEFSALHGKFHFPVGNVHLDSEQALGF
HHHCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHCCEEECCCCCEEECHHHHHHH
VRERYSLADGDRDRGRNQQKVIVAILQKLTSTEALKNYGTIINSLQDSIQTNMPLETMIN
HHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVNAQLESGGNYKVNSQDLKGTGRMDLPSYAMPDSNLYVLEIDDSSLAVVKAAIQDVMEG
HHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
R
C
>Mature Secondary Structure 
SRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFRYLNLVVTALVLLVAL
CCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNRLNAASNYSEYSISVAVLA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEE
DSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLTVNQSSSYLAAYKSLIAGETK
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCH
AIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAPKTSKNQSFNIYVSGIDTYGPIS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCEEEEEECCCCCCCHH
SVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKLTHAGIYGVDSSIHTLE
CCCCCCCEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCHHHHHCCCEECCCCHHHHHH
NLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQEFSALHGKFHFPVGNVHLDSEQALGF
HHHCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHCCEEECCCCCEEECHHHHHHH
VRERYSLADGDRDRGRNQQKVIVAILQKLTSTEALKNYGTIINSLQDSIQTNMPLETMIN
HHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVNAQLESGGNYKVNSQDLKGTGRMDLPSYAMPDSNLYVLEIDDSSLAVVKAAIQDVMEG
HHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]