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The map label for this gene is yegS [C]

Identifier: 169833007

GI number: 169833007

Start: 1054289

End: 1055173

Strand: Direct

Name: yegS [C]

Synonym: SPH_1146

Alternate gene names: 169833007

Gene position: 1054289-1055173 (Clockwise)

Preceding gene: 169833602

Following gene: 169832387

Centisome position: 46.95

GC content: 37.06

Gene sequence:

>885_bases
ATGAAAAAAGCAATGGTAATTATCAACCCTACTTCTGGTGGCGAGAAGGCTTTGGACTACAAAGAAAAGCTGGAGAATAA
AGCAAAAGAATACTTTGAATATGTTGAAACCAAAATTACCGAAAAAGCGCTGGATGCAACACATTTTGCTGAAGAAGCTT
CTCGTGAGCAGTATGATGCAGTGGTTGTGTTTGGTGGAGATGGAACTGTCAATGAAGTCATTTCAGGTATTGATGAGAGA
GACTACATTCCTAAGTTAGGGATTATCCCAGGCGGTACGGGTAACCTCATTACAAAACTTTTGGAAATCAATCAAGACAT
CGATGGCGCAATTGACGAACTGGATTTTGATTTAACCAATAAGATTGATATCGGTAAAGCAAATGACAACTATTTTGGTT
ATATCTTTAGTATCGGTTCTCTGCCTGAGGCGATTCACAATGTTGAAATAGAGGACAAAACAAAATTCGGTATTTTAACC
TATGCTGTAAATACCATGAAGTCTGTCATGACAGATCAGGTCTTTAACATTAAGGTTGAGACAGAAAATGGAAATTATGT
TGGTGAAGCTAGCCATGTTTTGGTCCTTTTGACAAATTACTTCGCTGATAAGAAAATCTTTGAAGAAAACAAGGACGGCT
ATGCCAACATTTTGATTCTGAAAGATGCCTCTATATTCTCCAAATTATCCGTCATTCCTGATTTATTAAAAGGGGATGTT
GTCGCAAATGATAATATCGAGTATATCAAAGCGCGTAATATTAAAATCTCTTCAGATAGTGAATTGGAGTCAGATGTTGA
CGGAGATAAATCAGATAACCTACCTGTAGAAATCAAAGTCCTAGCTCAGCGAGTAGAAGTATTTTCAAAACCGAAAGAGG
ATTAG

Upstream 100 bases:

>100_bases
TCAGATTTCTCTTTTCTGTATTTTCATTGTATAATAGGACTACATTTACTTGCATACGACGAAATGTAAACATTTCTGTT
TAAAATTAAGGATAAAATCA

Downstream 100 bases:

>100_bases
TATATAGAGAAAGCCTTTTTTAAGGCTTTTTGTATACTTTAAAAGATAGTTCCTTTAACAACGGACATTCCTTGTAAATA
GTTTACAAAAATAGTATACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDAVVVFGGDGTVNEVISGIDER
DYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDLLKGDV
VANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKED

Sequences:

>Translated_294_residues
MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDAVVVFGGDGTVNEVISGIDER
DYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDLLKGDV
VANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKED
>Mature_294_residues
MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDAVVVFGGDGTVNEVISGIDER
DYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDLLKGDV
VANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKED

Specific function: May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1045_STRPN (Q97QZ6)

Other databases:

- EMBL:   AE005672
- PIR:   G95120
- RefSeq:   NP_345520.1
- ProteinModelPortal:   Q97QZ6
- SMR:   Q97QZ6
- EnsemblBacteria:   EBSTRT00000026034
- GeneID:   931559
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_1045
- TIGR:   SP_1045
- GeneTree:   EBGT00050000027122
- HOGENOM:   HBG698136
- OMA:   FGFFPLG
- ProtClustDB:   CLSK559991
- BioCyc:   SPNE170187-1:SP_1045-MONOMER
- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206
- Gene3D:   G3DSA:3.40.50.10330
- SMART:   SM00046
- TIGRFAMs:   TIGR00147

Pfam domain/function: PF00781 DAGK_cat

EC number: NA

Molecular weight: Translated: 32682; Mature: 32682

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50146 DAGK

Important sites: ACT_SITE 269-269 BINDING 40-40 BINDING 93-93

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLTN
EEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
KIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILTYAVNTMKSVMTDQVFNIKVE
CEECCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
TENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDLLKGDV
ECCCCEECCCCEEEEEEEHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCE
VANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKED
EECCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLTN
EEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
KIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILTYAVNTMKSVMTDQVFNIKVE
CEECCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
TENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDLLKGDV
ECCCCEECCCCEEEEEEEHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCE
VANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKED
EECCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916