Click here to switch to the map view.

The map label for this gene is udk [H]

Identifier: 169825147

GI number: 169825147

Start: 1597980

End: 1598588

Strand: Direct

Name: udk [H]

Synonym: FMG_1450

Alternate gene names: 169825147

Gene position: 1597980-1598588 (Clockwise)

Preceding gene: 169825132

Following gene: 169825148

Centisome position: 88.9

GC content: 34.81

Gene sequence:

>609_bases
ATGAAACCGTATATTGTGGGAGTCGCAGGTGGAAGTGCTTCGGGTAAGACTGAAATCGTGAAGACTTTGAAAAAACATTT
TGAAGATAAAATAGAAATTATTGAACACGACAATTATTATTTCGCTCATGATGATTTGACAATGGAAGAACGTGCGAGTT
TGAATTACGATCATCCGCAATCTTTTGAAACGGATTTGTTGATTGAACACGTTAAAAAAATTATTAATAATGAAGAAATC
AACATTCCAACTTACGATTTTACAATTCACACTAGAAGCTCTGATACTTTGAAAAAAGTTCCTAAACCAATTGTGATTGT
CGAAGGAATTTTGGTCTTGGAAAACGAAGAACTTCGAAATTTGATGGATATGAAAGTTTTCGTTGACTGTGACGGAGATG
TCAGACTCAAAAGAAGAATTACAAGAGATGTTGTGGAACGTGACAGAACTATTGAATCGATTTTGACTCAATATATGGAA
ACTGTAAAGCCAATGCATGAACTTTTCGTCGAACCTAGTAAGAAATTTGCTGATTTGATTGTGCCAAAAGGCGGCAAGAA
TAAGGTTGCGATTGAGGTGCTTATCAATCATTTGGCTACGAAATTATAA

Upstream 100 bases:

>100_bases
TTTTTTTCATTTTTGAAAAGTCCTTTTGAAATGTTGTCTTGCTTTTTCTTGAAAAATTGTAAAATTTATATTAAAATTAA
CTAATAACTAGGAGGCTATT

Downstream 100 bases:

>100_bases
AAAAAACATTTTGCTATTGACTAGAATTGGATTCTAGTATAAAATTTTAATAACTTAATAGAAAATTATGATTGTGACCA
GTACCGATTATTCGGGAATT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKPYIVGVAGGSASGKTEIVKTLKKHFEDKIEIIEHDNYYFAHDDLTMEERASLNYDHPQSFETDLLIEHVKKIINNEEI
NIPTYDFTIHTRSSDTLKKVPKPIVIVEGILVLENEELRNLMDMKVFVDCDGDVRLKRRITRDVVERDRTIESILTQYME
TVKPMHELFVEPSKKFADLIVPKGGKNKVAIEVLINHLATKL

Sequences:

>Translated_202_residues
MKPYIVGVAGGSASGKTEIVKTLKKHFEDKIEIIEHDNYYFAHDDLTMEERASLNYDHPQSFETDLLIEHVKKIINNEEI
NIPTYDFTIHTRSSDTLKKVPKPIVIVEGILVLENEELRNLMDMKVFVDCDGDVRLKRRITRDVVERDRTIESILTQYME
TVKPMHELFVEPSKKFADLIVPKGGKNKVAIEVLINHLATKL
>Mature_202_residues
MKPYIVGVAGGSASGKTEIVKTLKKHFEDKIEIIEHDNYYFAHDDLTMEERASLNYDHPQSFETDLLIEHVKKIINNEEI
NIPTYDFTIHTRSSDTLKKVPKPIVIVEGILVLENEELRNLMDMKVFVDCDGDVRLKRRITRDVVERDRTIESILTQYME
TVKPMHELFVEPSKKFADLIVPKGGKNKVAIEVLINHLATKL

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=210, Percent_Identity=39.5238095238095, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI13899253, Length=210, Percent_Identity=39.0476190476191, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=36.1386138613861, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=36.1386138613861, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI209863022, Length=152, Percent_Identity=34.8684210526316, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI87082034, Length=195, Percent_Identity=44.1025641025641, Blast_Score=184, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17539894, Length=203, Percent_Identity=39.4088669950739, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17539892, Length=203, Percent_Identity=39.4088669950739, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71981181, Length=208, Percent_Identity=34.1346153846154, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324339, Length=176, Percent_Identity=35.2272727272727, Blast_Score=111, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320223, Length=87, Percent_Identity=32.183908045977, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649624, Length=212, Percent_Identity=37.7358490566038, Blast_Score=160, Evalue=4e-40,
Organism=Drosophila melanogaster, GI221458995, Length=211, Percent_Identity=37.914691943128, Blast_Score=160, Evalue=5e-40,
Organism=Drosophila melanogaster, GI28573516, Length=205, Percent_Identity=35.609756097561, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI28573514, Length=205, Percent_Identity=35.609756097561, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI28573512, Length=205, Percent_Identity=35.609756097561, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI45550449, Length=205, Percent_Identity=35.609756097561, Blast_Score=157, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23289; Mature: 23289

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPYIVGVAGGSASGKTEIVKTLKKHFEDKIEIIEHDNYYFAHDDLTMEERASLNYDHPQ
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCHHHHHCCCCCCCC
SFETDLLIEHVKKIINNEEINIPTYDFTIHTRSSDTLKKVPKPIVIVEGILVLENEELRN
CCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHCCCCEEEECCEEEECCHHHHH
LMDMKVFVDCDGDVRLKRRITRDVVERDRTIESILTQYMETVKPMHELFVEPSKKFADLI
HHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
VPKGGKNKVAIEVLINHLATKL
CCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPYIVGVAGGSASGKTEIVKTLKKHFEDKIEIIEHDNYYFAHDDLTMEERASLNYDHPQ
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCHHHHHCCCCCCCC
SFETDLLIEHVKKIINNEEINIPTYDFTIHTRSSDTLKKVPKPIVIVEGILVLENEELRN
CCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHCCCCEEEECCEEEECCHHHHH
LMDMKVFVDCDGDVRLKRRITRDVVERDRTIESILTQYMETVKPMHELFVEPSKKFADLI
HHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
VPKGGKNKVAIEVLINHLATKL
CCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA