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The map label for this gene is yvrH [H]

Identifier: 169825106

GI number: 169825106

Start: 1553812

End: 1554507

Strand: Direct

Name: yvrH [H]

Synonym: FMG_1409

Alternate gene names: 169825106

Gene position: 1553812-1554507 (Clockwise)

Preceding gene: 169825102

Following gene: 169825107

Centisome position: 86.44

GC content: 35.34

Gene sequence:

>696_bases
ATGGATTTTAGAAATAATTTTTCTATACTAATAGTAGATGACGAAACAAATTTATTGGAAAATTTATATAATTTTTTGAA
AGAAAAGGGTTTTAATAAGATTTATACCGCCAAAAACCTCAAAGAATCTAGGTTTAAGCTTACAAATTTCAAAATTGACC
TAGTGGTCCTTGACCTAATGCTACCCGACGGGAGCGGTTTTGATCTTTTAAAGGAAATAAGAAAAACTTCCGATATGGCA
GTCATAATCCTCTCCGCCCTTGATGGGATAGATGATAGGAAGGAAGGTTTTGAAAACAAGGCCGACGACTACCTAGTCAA
GCCATTTTTCCCTGATGAACTCCTTTGGAGGATTGATGCGGTTTTAAGACGCAGTAAAAATATAAAAAACGAAGAGAAAA
TTAATTTAGGAAAGGTAATTTTCGATAAGTCCAAGGGCATCCTCATAAAAAATGGAGAGGAAATCCCCCTAACTGCCACG
CAATTTAAAATCCTGTCCTACCTAGCCGACAACATGAATATGATTGTCTCTATTGACCGCATTTTGGAAAATATTTGGGA
AGATTCCTATGGTTATGAAAATACATTGATAACTCACATTTACAGGATTCGTGAAAAACTCGAAGACAATCCTAGAGATC
CAAAAATCCTAATTACCATCAAGGGTTTGGGCTATAAACTGGTGAAGGAAGATTAA

Upstream 100 bases:

>100_bases
GGCTAAGATAAAAATAAGCTTTAAGCAAGGTCACTTTTACATCACAAAAACCAAAATATCAAAAGTCTGGTGTATAATTA
GGATAGCAAGGAGGAGCTTA

Downstream 100 bases:

>100_bases
GATGTTTAATTACATTATAAAAAGATTTAAAAAAATCGTAATAAGAATCCTTGCCCTTTTATTTTTTCTGACATTTTTGC
TAATGGTCTTTCTCTACCTC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MDFRNNFSILIVDDETNLLENLYNFLKEKGFNKIYTAKNLKESRFKLTNFKIDLVVLDLMLPDGSGFDLLKEIRKTSDMA
VIILSALDGIDDRKEGFENKADDYLVKPFFPDELLWRIDAVLRRSKNIKNEEKINLGKVIFDKSKGILIKNGEEIPLTAT
QFKILSYLADNMNMIVSIDRILENIWEDSYGYENTLITHIYRIREKLEDNPRDPKILITIKGLGYKLVKED

Sequences:

>Translated_231_residues
MDFRNNFSILIVDDETNLLENLYNFLKEKGFNKIYTAKNLKESRFKLTNFKIDLVVLDLMLPDGSGFDLLKEIRKTSDMA
VIILSALDGIDDRKEGFENKADDYLVKPFFPDELLWRIDAVLRRSKNIKNEEKINLGKVIFDKSKGILIKNGEEIPLTAT
QFKILSYLADNMNMIVSIDRILENIWEDSYGYENTLITHIYRIREKLEDNPRDPKILITIKGLGYKLVKED
>Mature_231_residues
MDFRNNFSILIVDDETNLLENLYNFLKEKGFNKIYTAKNLKESRFKLTNFKIDLVVLDLMLPDGSGFDLLKEIRKTSDMA
VIILSALDGIDDRKEGFENKADDYLVKPFFPDELLWRIDAVLRRSKNIKNEEKINLGKVIFDKSKGILIKNGEEIPLTAT
QFKILSYLADNMNMIVSIDRILENIWEDSYGYENTLITHIYRIREKLEDNPRDPKILITIKGLGYKLVKED

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.2869955156951, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=33.4745762711864, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=30.6306306306306, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=32.1266968325792, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=34.4978165938865, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.2576419213974, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=31.2217194570136, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=30.4932735426009, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.4561403508772, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=28.7610619469027, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=28.6363636363636, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=28.936170212766, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI145693140, Length=190, Percent_Identity=25.7894736842105, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26934; Mature: 26934

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRNNFSILIVDDETNLLENLYNFLKEKGFNKIYTAKNLKESRFKLTNFKIDLVVLDLM
CCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEHHCCCHHHHEEEECEEEEEEEEEEE
LPDGSGFDLLKEIRKTSDMAVIILSALDGIDDRKEGFENKADDYLVKPFFPDELLWRIDA
CCCCCCHHHHHHHHHCCCCEEEEEHHHCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHH
VLRRSKNIKNEEKINLGKVIFDKSKGILIKNGEEIPLTATQFKILSYLADNMNMIVSIDR
HHHHHCCCCCCHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHEEEHHH
ILENIWEDSYGYENTLITHIYRIREKLEDNPRDPKILITIKGLGYKLVKED
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCC
>Mature Secondary Structure
MDFRNNFSILIVDDETNLLENLYNFLKEKGFNKIYTAKNLKESRFKLTNFKIDLVVLDLM
CCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEHHCCCHHHHEEEECEEEEEEEEEEE
LPDGSGFDLLKEIRKTSDMAVIILSALDGIDDRKEGFENKADDYLVKPFFPDELLWRIDA
CCCCCCHHHHHHHHHCCCCEEEEEHHHCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHH
VLRRSKNIKNEEKINLGKVIFDKSKGILIKNGEEIPLTATQFKILSYLADNMNMIVSIDR
HHHHHCCCCCCHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHEEEHHH
ILENIWEDSYGYENTLITHIYRIREKLEDNPRDPKILITIKGLGYKLVKED
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]