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The map label for this gene is yvrG [H]

Identifier: 169825107

GI number: 169825107

Start: 1554509

End: 1555804

Strand: Direct

Name: yvrG [H]

Synonym: FMG_1410

Alternate gene names: 169825107

Gene position: 1554509-1555804 (Clockwise)

Preceding gene: 169825106

Following gene: 169825115

Centisome position: 86.48

GC content: 31.79

Gene sequence:

>1296_bases
ATGTTTAATTACATTATAAAAAGATTTAAAAAAATCGTAATAAGAATCCTTGCCCTTTTATTTTTTCTGACATTTTTGCT
AATGGTCTTTCTCTACCTCAACTACAGGTTGGGAGATAAATATCCAAATCCTAATGATGTTTATACTTATATAACTAATA
ACAAAACAGATACCTATCTCAACGAAAATAATAAGAACTTTTTAAAAGAAAATGATATTCGGGCCCTAAGGCTCGATAAA
AATGGCAAAGTCATCGAATCTTTCAACAAGCCAAGAGAGGTTAAAAATAAATTCGAGATCACAGATGTAGTTAGCTTTAA
CAGGTATTACTTGGCTGATTATCCCGTTTTTACCTATATTGTAGGAGACGGCATAATCCTTTTTGCCTATCCAAAAAATT
CACTAGATAAATTGCCCTTTAATTATTATAACTACCAGAACCTTGTATTTAATATGTGGCTAGTAGTCATATTTATAGTT
TTATTTTTGCTCTTTGTCTATGTTTTTTACAGGATGGATATAAGGGATATACTTAAAAATATTGCTCCTTTTCAAAAGGC
CATTGACGGGCTTTTTGAAGATGACTATGAAAAATTAGATGAAAGTGGAGAATTAAGAGACCTCGCCCTTTCAATTAACA
AGGCAAACGAAAAATATAATAACTTAAAAAAATCACAAAGTAAGTGGATAAGGGGAGTTAGCCACGATGTTAGGACCCCT
CTTGCAAAAATTTCCTGGGAACTTAATAAAGAAAATAAAAATGACCTCGATACAAAAAATATCCAAGACCAAGTTTTAAA
AATTTCAAATATTTTAGAAGGTCTCAATCTAACTATGTCCCTTGCCAACATCGACAAGGAGAATTTTGAGTCAAAAAGTC
CCTTAAAAGTAATCCGAAAAGTCATAGTCGATAAGTTAAATGAAAACCCAAAAAGAGAAATTATTTTTGAAAATAGGCTA
AGAGATCCAGATATAAAACTTAAAATGGATCCAACCTTGTTTTATAGGATGGTCGAAAATATCATAAAAAATTCCCTTGC
CTATACCGAGGGAAAAATCTACCTTATAATTTCAAACCCAGATAACCAGCTAATTATAAGGGTCTTAGACCAAGGCTGTG
GGGTAGATGAAGATATAATAAAGAGAATTAATGACGAAGATTTGACCAATATTACAAGGCACGGTTTGGGGATTTTTATT
TCTAAACAAATAGCCGAATTGCATGATGGGAAATTTTCTATAGAGAATAAGGACCAAGGCCTTGACGTTTCCTTTATCTT
TGACCTGGTTAATTAA

Upstream 100 bases:

>100_bases
ATTTACAGGATTCGTGAAAAACTCGAAGACAATCCTAGAGATCCAAAAATCCTAATTACCATCAAGGGTTTGGGCTATAA
ACTGGTGAAGGAAGATTAAG

Downstream 100 bases:

>100_bases
ATTTTATTTTAATCATAAATCACAATTAAAAAACGAGCCAGCAAGAAAATCATGTACCGACCTCCCAATCGTTAGATTTT
GGTATAACTTTTTGAGGTCG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MFNYIIKRFKKIVIRILALLFFLTFLLMVFLYLNYRLGDKYPNPNDVYTYITNNKTDTYLNENNKNFLKENDIRALRLDK
NGKVIESFNKPREVKNKFEITDVVSFNRYYLADYPVFTYIVGDGIILFAYPKNSLDKLPFNYYNYQNLVFNMWLVVIFIV
LFLLFVYVFYRMDIRDILKNIAPFQKAIDGLFEDDYEKLDESGELRDLALSINKANEKYNNLKKSQSKWIRGVSHDVRTP
LAKISWELNKENKNDLDTKNIQDQVLKISNILEGLNLTMSLANIDKENFESKSPLKVIRKVIVDKLNENPKREIIFENRL
RDPDIKLKMDPTLFYRMVENIIKNSLAYTEGKIYLIISNPDNQLIIRVLDQGCGVDEDIIKRINDEDLTNITRHGLGIFI
SKQIAELHDGKFSIENKDQGLDVSFIFDLVN

Sequences:

>Translated_431_residues
MFNYIIKRFKKIVIRILALLFFLTFLLMVFLYLNYRLGDKYPNPNDVYTYITNNKTDTYLNENNKNFLKENDIRALRLDK
NGKVIESFNKPREVKNKFEITDVVSFNRYYLADYPVFTYIVGDGIILFAYPKNSLDKLPFNYYNYQNLVFNMWLVVIFIV
LFLLFVYVFYRMDIRDILKNIAPFQKAIDGLFEDDYEKLDESGELRDLALSINKANEKYNNLKKSQSKWIRGVSHDVRTP
LAKISWELNKENKNDLDTKNIQDQVLKISNILEGLNLTMSLANIDKENFESKSPLKVIRKVIVDKLNENPKREIIFENRL
RDPDIKLKMDPTLFYRMVENIIKNSLAYTEGKIYLIISNPDNQLIIRVLDQGCGVDEDIIKRINDEDLTNITRHGLGIFI
SKQIAELHDGKFSIENKDQGLDVSFIFDLVN
>Mature_431_residues
MFNYIIKRFKKIVIRILALLFFLTFLLMVFLYLNYRLGDKYPNPNDVYTYITNNKTDTYLNENNKNFLKENDIRALRLDK
NGKVIESFNKPREVKNKFEITDVVSFNRYYLADYPVFTYIVGDGIILFAYPKNSLDKLPFNYYNYQNLVFNMWLVVIFIV
LFLLFVYVFYRMDIRDILKNIAPFQKAIDGLFEDDYEKLDESGELRDLALSINKANEKYNNLKKSQSKWIRGVSHDVRTP
LAKISWELNKENKNDLDTKNIQDQVLKISNILEGLNLTMSLANIDKENFESKSPLKVIRKVIVDKLNENPKREIIFENRL
RDPDIKLKMDPTLFYRMVENIIKNSLAYTEGKIYLIISNPDNQLIIRVLDQGCGVDEDIIKRINDEDLTNITRHGLGIFI
SKQIAELHDGKFSIENKDQGLDVSFIFDLVN

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=446, Percent_Identity=21.52466367713, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=21.5547703180212, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50761; Mature: 50761

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNYIIKRFKKIVIRILALLFFLTFLLMVFLYLNYRLGDKYPNPNDVYTYITNNKTDTYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEE
NENNKNFLKENDIRALRLDKNGKVIESFNKPREVKNKFEITDVVSFNRYYLADYPVFTYI
CCCCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHEEECCCEEEECCCEEEEE
VGDGIILFAYPKNSLDKLPFNYYNYQNLVFNMWLVVIFIVLFLLFVYVFYRMDIRDILKN
ECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IAPFQKAIDGLFEDDYEKLDESGELRDLALSINKANEKYNNLKKSQSKWIRGVSHDVRTP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
LAKISWELNKENKNDLDTKNIQDQVLKISNILEGLNLTMSLANIDKENFESKSPLKVIRK
HHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHCCHHCCCCCCHHHHHHH
VIVDKLNENPKREIIFENRLRDPDIKLKMDPTLFYRMVENIIKNSLAYTEGKIYLIISNP
HHHHHHCCCCCHHHEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHEECCEEEEEEECC
DNQLIIRVLDQGCGVDEDIIKRINDEDLTNITRHGLGIFISKQIAELHDGKFSIENKDQG
CCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCC
LDVSFIFDLVN
CCHHHHHEECC
>Mature Secondary Structure
MFNYIIKRFKKIVIRILALLFFLTFLLMVFLYLNYRLGDKYPNPNDVYTYITNNKTDTYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEE
NENNKNFLKENDIRALRLDKNGKVIESFNKPREVKNKFEITDVVSFNRYYLADYPVFTYI
CCCCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHEEECCCEEEECCCEEEEE
VGDGIILFAYPKNSLDKLPFNYYNYQNLVFNMWLVVIFIVLFLLFVYVFYRMDIRDILKN
ECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IAPFQKAIDGLFEDDYEKLDESGELRDLALSINKANEKYNNLKKSQSKWIRGVSHDVRTP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
LAKISWELNKENKNDLDTKNIQDQVLKISNILEGLNLTMSLANIDKENFESKSPLKVIRK
HHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHCCHHCCCCCCHHHHHHH
VIVDKLNENPKREIIFENRLRDPDIKLKMDPTLFYRMVENIIKNSLAYTEGKIYLIISNP
HHHHHHCCCCCHHHEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHEECCEEEEEEECC
DNQLIIRVLDQGCGVDEDIIKRINDEDLTNITRHGLGIFISKQIAELHDGKFSIENKDQG
CCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCC
LDVSFIFDLVN
CCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]