BacMap

Definition	Finegoldia magna ATCC 29328 chromosome, complete genome.
Accession	NC_010376
Length	1,797,577

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The map label for this gene is ppiB [C]

Identifier: 169824411

GI number: 169824411

Start: 778196

End: 778780

Strand: Direct

Name: ppiB [C]

Synonym: FMG_0714

Alternate gene names: 169824411

Gene position: 778196-778780 (Clockwise)

Preceding gene: 169824410

Following gene: 169824412

Centisome position: 43.29

GC content: 28.55

Gene sequence:

>585_bases
ATGTATCAAACAGATATACCTAAAAAAGATCAATTAATTGCAAATATAACTACAAATTTAGGAGAAATAAAAATTTGCTT
GTTTGAAAATGATGCTCCAAATTGTGTAGAAAACTTTGTGACTCATGCAAAAGAAGGATATTATGATGGAACAATTTTTC
ATAGAGTTATTAAAGATTTTATGATTCAAGGAGGAGATCCACAAGGAAGTGGATACGGCGGAGAAAGCATTTGGAAAAAG
CCATTTGAAGATGAATTTTCTGAAAATTTAAAAAATATAAGAGGAGCATTATCAATGGCTAATTCTGGGCCAAATACAAA
TGGATCTCAATTCTTCATAGTTCAAAATAATTCAATTAGAAAAGATTATATTAAATATCTTGATGAATGTGATTTGAACG
AAGAACAAAAAGATTTTTATAAAAATAATGGCGGTTGTTTTTGGTTAGATGGAAAGCATTCTGTATTTGGGCAAGTTTTT
GAAGGAATGGAAGTTGTCGATAAAATCGCAAAAGTAGATACTGATTTTTCAGATAAACCTTTAGAAGATATTATGATTAA
ATCAATAGAAATTTCAAGGAGTTAG

Upstream 100 bases:

>100_bases
ATAATAATAAGAACAAAATGGGGAGAAGGATATTACTTCTCTTCAAATACAAAACTTTAAACTGCTTTTATAAAGCAGTT
TAATTATTTATGGAGGAAAT

Downstream 100 bases:

>100_bases
TATGCATCAATATAAAGGTAAATTAATAGTGCATACCGGATCTATGTTTTCTGGGAAAACATCTAGTTTGTGGAAAGAAG
TAAATAGATTTAAGATTGCT

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MYQTDIPKKDQLIANITTNLGEIKICLFENDAPNCVENFVTHAKEGYYDGTIFHRVIKDFMIQGGDPQGSGYGGESIWKK
PFEDEFSENLKNIRGALSMANSGPNTNGSQFFIVQNNSIRKDYIKYLDECDLNEEQKDFYKNNGGCFWLDGKHSVFGQVF
EGMEVVDKIAKVDTDFSDKPLEDIMIKSIEISRS

Sequences:

>Translated_194_residues
MYQTDIPKKDQLIANITTNLGEIKICLFENDAPNCVENFVTHAKEGYYDGTIFHRVIKDFMIQGGDPQGSGYGGESIWKK
PFEDEFSENLKNIRGALSMANSGPNTNGSQFFIVQNNSIRKDYIKYLDECDLNEEQKDFYKNNGGCFWLDGKHSVFGQVF
EGMEVVDKIAKVDTDFSDKPLEDIMIKSIEISRS
>Mature_194_residues
MYQTDIPKKDQLIANITTNLGEIKICLFENDAPNCVENFVTHAKEGYYDGTIFHRVIKDFMIQGGDPQGSGYGGESIWKK
PFEDEFSENLKNIRGALSMANSGPNTNGSQFFIVQNNSIRKDYIKYLDECDLNEEQKDFYKNNGGCFWLDGKHSVFGQVF
EGMEVVDKIAKVDTDFSDKPLEDIMIKSIEISRS

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI24308049, Length=191, Percent_Identity=44.5026178010471, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI7706339, Length=172, Percent_Identity=43.0232558139535, Blast_Score=141, Evalue=3e-34,
Organism=Homo sapiens, GI19557636, Length=182, Percent_Identity=42.3076923076923, Blast_Score=137, Evalue=5e-33,
Organism=Homo sapiens, GI4758950, Length=172, Percent_Identity=42.4418604651163, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI22547215, Length=178, Percent_Identity=42.1348314606742, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI64276486, Length=179, Percent_Identity=37.9888268156425, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI22547212, Length=178, Percent_Identity=42.1348314606742, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI7657473, Length=178, Percent_Identity=42.1348314606742, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI4505991, Length=172, Percent_Identity=43.6046511627907, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI5454154, Length=176, Percent_Identity=40.9090909090909, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI45439316, Length=155, Percent_Identity=41.2903225806452, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI10863927, Length=156, Percent_Identity=40.3846153846154, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI42560244, Length=179, Percent_Identity=36.8715083798883, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI303305009, Length=153, Percent_Identity=41.1764705882353, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI5174637, Length=153, Percent_Identity=41.1764705882353, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI20911035, Length=181, Percent_Identity=34.2541436464088, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI5031987, Length=155, Percent_Identity=42.5806451612903, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI6631100, Length=180, Percent_Identity=36.6666666666667, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI256017253, Length=152, Percent_Identity=39.4736842105263, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI221139811, Length=152, Percent_Identity=39.4736842105263, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI256017251, Length=152, Percent_Identity=39.4736842105263, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI310129267, Length=161, Percent_Identity=37.888198757764, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI310120620, Length=161, Percent_Identity=37.888198757764, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI4826932, Length=180, Percent_Identity=36.1111111111111, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI178057341, Length=154, Percent_Identity=38.3116883116883, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI209417936, Length=154, Percent_Identity=38.3116883116883, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI30102944, Length=154, Percent_Identity=38.3116883116883, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI219842199, Length=154, Percent_Identity=38.3116883116883, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI310110104, Length=154, Percent_Identity=37.6623376623377, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI169164185, Length=155, Percent_Identity=38.7096774193548, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI169163623, Length=155, Percent_Identity=38.7096774193548, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI169163387, Length=155, Percent_Identity=38.7096774193548, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI14277126, Length=124, Percent_Identity=41.1290322580645, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI310127646, Length=163, Percent_Identity=34.9693251533742, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI310114371, Length=163, Percent_Identity=34.9693251533742, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI310119221, Length=163, Percent_Identity=34.9693251533742, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI150418007, Length=154, Percent_Identity=38.961038961039, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI310132444, Length=156, Percent_Identity=33.974358974359, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI310113152, Length=156, Percent_Identity=33.974358974359, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI239751853, Length=154, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI113428306, Length=154, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI169214050, Length=154, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI310127745, Length=147, Percent_Identity=36.0544217687075, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI310119290, Length=147, Percent_Identity=36.0544217687075, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI310114540, Length=147, Percent_Identity=36.0544217687075, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI27735045, Length=181, Percent_Identity=30.3867403314917, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786736, Length=182, Percent_Identity=37.9120879120879, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1789763, Length=184, Percent_Identity=33.1521739130435, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17539496, Length=170, Percent_Identity=46.4705882352941, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17532641, Length=185, Percent_Identity=40.5405405405405, Blast_Score=142, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17506311, Length=181, Percent_Identity=45.8563535911602, Blast_Score=141, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71980594, Length=181, Percent_Identity=39.2265193370166, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71980590, Length=171, Percent_Identity=40.3508771929825, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71997782, Length=169, Percent_Identity=39.0532544378698, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17552780, Length=172, Percent_Identity=41.8604651162791, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17506307, Length=174, Percent_Identity=40.2298850574713, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17559074, Length=177, Percent_Identity=38.4180790960452, Blast_Score=102, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17539498, Length=175, Percent_Identity=38.8571428571429, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565860, Length=177, Percent_Identity=37.8531073446328, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566266, Length=160, Percent_Identity=38.125, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551282, Length=177, Percent_Identity=38.4180790960452, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17551284, Length=177, Percent_Identity=38.4180790960452, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32563659, Length=179, Percent_Identity=31.8435754189944, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17552784, Length=180, Percent_Identity=36.6666666666667, Blast_Score=93, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17552782, Length=160, Percent_Identity=37.5, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17532643, Length=177, Percent_Identity=40.6779661016949, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321848, Length=173, Percent_Identity=41.6184971098266, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323562, Length=174, Percent_Identity=40.8045977011494, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320510, Length=172, Percent_Identity=39.5348837209302, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320359, Length=176, Percent_Identity=36.3636363636364, Blast_Score=101, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6323246, Length=184, Percent_Identity=36.9565217391304, Blast_Score=85, Evalue=9e-18,
Organism=Drosophila melanogaster, GI19922376, Length=177, Percent_Identity=44.0677966101695, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI17986117, Length=181, Percent_Identity=41.9889502762431, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19922912, Length=179, Percent_Identity=46.3687150837989, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20130249, Length=171, Percent_Identity=42.1052631578947, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21357249, Length=100, Percent_Identity=50, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24652460, Length=178, Percent_Identity=34.8314606741573, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24650807, Length=179, Percent_Identity=37.4301675977654, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17647301, Length=173, Percent_Identity=41.6184971098266, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586038, Length=183, Percent_Identity=38.7978142076503, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45549139, Length=154, Percent_Identity=41.5584415584416, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24664125, Length=169, Percent_Identity=38.4615384615385, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357783, Length=169, Percent_Identity=38.4615384615385, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17136360, Length=175, Percent_Identity=36.5714285714286, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355677, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 22039; Mature: 22039

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQTDIPKKDQLIANITTNLGEIKICLFENDAPNCVENFVTHAKEGYYDGTIFHRVIKDF
CCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
MIQGGDPQGSGYGGESIWKKPFEDEFSENLKNIRGALSMANSGPNTNGSQFFIVQNNSIR
HHCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCH
KDYIKYLDECDLNEEQKDFYKNNGGCFWLDGKHSVFGQVFEGMEVVDKIAKVDTDFSDKP
HHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LEDIMIKSIEISRS
HHHHHHHHHHCCCC
>Mature Secondary Structure
MYQTDIPKKDQLIANITTNLGEIKICLFENDAPNCVENFVTHAKEGYYDGTIFHRVIKDF
CCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
MIQGGDPQGSGYGGESIWKKPFEDEFSENLKNIRGALSMANSGPNTNGSQFFIVQNNSIR
HHCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCH
KDYIKYLDECDLNEEQKDFYKNNGGCFWLDGKHSVFGQVFEGMEVVDKIAKVDTDFSDKP
HHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LEDIMIKSIEISRS
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA