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The map label for this gene is tdk [H]

Identifier: 169824412

GI number: 169824412

Start: 778782

End: 779414

Strand: Direct

Name: tdk [H]

Synonym: FMG_0715

Alternate gene names: 169824412

Gene position: 778782-779414 (Clockwise)

Preceding gene: 169824411

Following gene: 169824415

Centisome position: 43.32

GC content: 30.02

Gene sequence:

>633_bases
ATGCATCAATATAAAGGTAAATTAATAGTGCATACCGGATCTATGTTTTCTGGGAAAACATCTAGTTTGTGGAAAGAAGT
AAATAGATTTAAGATTGCTAAATATAATGTTGTTGTATTTAAACCGAGGATGGATTCTAGATATTCCAAGGAAAAAGTAG
TAACTCATGATAAAAACGAAATAGAAGCAATAAATGTTGATAATATTGATGATATAGTCGAGTATACAAAAACTCATGAT
GTTAATGTAATTGCAATAGATGAGATACAATTTATAAATTCTAAAGCTGATCATTTTGTAAAACAAATTAATTATCTTTT
AGAGAAAGGATTTACAATAATAGCTGCTGGTCTTGACATGGACTATAAAGCCAAGCCATTTCAACTTGTCAAGGAATTAT
TACCAATATGTGATTACGTAGAAAAGCATCATGCGGTGTGTGCTGTATGTGGAAACGACGCATGGGTAAGTTATCGTATA
TCAGACGATAAAAACAGAATACAGTTGGGAGCTAATGAAGCATATATGCCGTTATGTAGAAAACATTATATTGAAAAAAT
GAATGAGAAGAGATTTACTGAACTTCAAACAACGTATTTAGATAAAAATAGAGCAAAGAAAAACACAATTTAG

Upstream 100 bases:

>100_bases
ATGGAAGTTGTCGATAAAATCGCAAAAGTAGATACTGATTTTTCAGATAAACCTTTAGAAGATATTATGATTAAATCAAT
AGAAATTTCAAGGAGTTAGT

Downstream 100 bases:

>100_bases
ATAAACTAAATTGTGTTTTTTCTATTCTGGATATATTAAATTTTCTTTTTTTATGTTATTTATAACATTTAAATATTTAT
TAGAGTAGAATTTCGCCATA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MHQYKGKLIVHTGSMFSGKTSSLWKEVNRFKIAKYNVVVFKPRMDSRYSKEKVVTHDKNEIEAINVDNIDDIVEYTKTHD
VNVIAIDEIQFINSKADHFVKQINYLLEKGFTIIAAGLDMDYKAKPFQLVKELLPICDYVEKHHAVCAVCGNDAWVSYRI
SDDKNRIQLGANEAYMPLCRKHYIEKMNEKRFTELQTTYLDKNRAKKNTI

Sequences:

>Translated_210_residues
MHQYKGKLIVHTGSMFSGKTSSLWKEVNRFKIAKYNVVVFKPRMDSRYSKEKVVTHDKNEIEAINVDNIDDIVEYTKTHD
VNVIAIDEIQFINSKADHFVKQINYLLEKGFTIIAAGLDMDYKAKPFQLVKELLPICDYVEKHHAVCAVCGNDAWVSYRI
SDDKNRIQLGANEAYMPLCRKHYIEKMNEKRFTELQTTYLDKNRAKKNTI
>Mature_210_residues
MHQYKGKLIVHTGSMFSGKTSSLWKEVNRFKIAKYNVVVFKPRMDSRYSKEKVVTHDKNEIEAINVDNIDDIVEYTKTHD
VNVIAIDEIQFINSKADHFVKQINYLLEKGFTIIAAGLDMDYKAKPFQLVKELLPICDYVEKHHAVCAVCGNDAWVSYRI
SDDKNRIQLGANEAYMPLCRKHYIEKMNEKRFTELQTTYLDKNRAKKNTI

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=184, Percent_Identity=34.2391304347826, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17543396, Length=200, Percent_Identity=32, Blast_Score=106, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 24471; Mature: 24471

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQYKGKLIVHTGSMFSGKTSSLWKEVNRFKIAKYNVVVFKPRMDSRYSKEKVVTHDKNE
CCCCCCEEEEEECCCCCCCHHHHHHHHHHEEEEEEEEEEECCCCCCCCCCCCCEECCCCC
IEAINVDNIDDIVEYTKTHDVNVIAIDEIQFINSKADHFVKQINYLLEKGFTIIAAGLDM
EEEECCCCHHHHHHHHHCCCCEEEEECCEEECCCHHHHHHHHHHHHHHCCCEEEEECCCC
DYKAKPFQLVKELLPICDYVEKHHAVCAVCGNDAWVSYRISDDKNRIQLGANEAYMPLCR
CCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCEEEECCCCHHHHHHH
KHYIEKMNEKRFTELQTTYLDKNRAKKNTI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHQYKGKLIVHTGSMFSGKTSSLWKEVNRFKIAKYNVVVFKPRMDSRYSKEKVVTHDKNE
CCCCCCEEEEEECCCCCCCHHHHHHHHHHEEEEEEEEEEECCCCCCCCCCCCCEECCCCC
IEAINVDNIDDIVEYTKTHDVNVIAIDEIQFINSKADHFVKQINYLLEKGFTIIAAGLDM
EEEECCCCHHHHHHHHHCCCCEEEEECCEEECCCHHHHHHHHHHHHHHCCCEEEEECCCC
DYKAKPFQLVKELLPICDYVEKHHAVCAVCGNDAWVSYRISDDKNRIQLGANEAYMPLCR
CCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCEEEECCCCHHHHHHH
KHYIEKMNEKRFTELQTTYLDKNRAKKNTI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA