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The map label for this gene is infC [H]

Identifier: 169824392

GI number: 169824392

Start: 761435

End: 762013

Strand: Direct

Name: infC [H]

Synonym: FMG_0695

Alternate gene names: 169824392

Gene position: 761435-762013 (Clockwise)

Preceding gene: 169824391

Following gene: 169824393

Centisome position: 42.36

GC content: 29.19

Gene sequence:

>579_bases
TTGATTATTAATTTTTGGCGGGTATCTTTACCCGCCATTATTTTTTTGGAGGTGAATAATATAAAAGACTTAATGATTAA
TGAGGAGATAAGATCTTCTAAAGTTAGATTAATCGATGACGAAGGTGAACAAATAGGTGTAATTCCTATAAAAGAAGCTT
TAAAAATGGCTGAAGATAAACATCTTGATTTGGTTAATGTAGCACCAAATGCTAAGCCACCTGTATGCAAAATATTAGAT
TATGGAAAATATAAATACGATGCATTAAAGAAGGAAAAAGAAGCAAAGAAAAATCAAAAAGTAATAAACGTAAAAGAAAT
AAGACTTTCACCAAATATTGAAAAGCACGACTTAGAAGTTAAAGCTAACCAAGCATCAAAGTTTTTAAGTAATGAAAACA
GAGTTAAAGTTTCTGTTAGATTTAGAGGTAGAGAACTTGGTCATAAAGATTTGGGTAAAGAAGTTCTTGATAAATTTTAT
GAATTAACAAAAGATGTAGGACAAATAGAAAAGAAACCTTCTATGGAAGGTAGAATGATGATAATGTTTATGGGTCCTTT
GACTGATAAAGATAATTAG

Upstream 100 bases:

>100_bases
GTTGACAAAGTGCTCATCATGGTATACAATATTTGTTGTTGATAAGTAGAGGTATCCGCTCTCACCTTATAATTTCGAAT
TCATAAGGTTAAAATTTAAT

Downstream 100 bases:

>100_bases
AGGGGGAAATAATATGCCAAAAATGAAGACACATAGAGGTTCTGCTAAAAGATTTAGAAGAACTGGTACAGGTAAGTTAA
GAAGATTTAAAGCTTATGCA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MIINFWRVSLPAIIFLEVNNIKDLMINEEIRSSKVRLIDDEGEQIGVIPIKEALKMAEDKHLDLVNVAPNAKPPVCKILD
YGKYKYDALKKEKEAKKNQKVINVKEIRLSPNIEKHDLEVKANQASKFLSNENRVKVSVRFRGRELGHKDLGKEVLDKFY
ELTKDVGQIEKKPSMEGRMMIMFMGPLTDKDN

Sequences:

>Translated_192_residues
MIINFWRVSLPAIIFLEVNNIKDLMINEEIRSSKVRLIDDEGEQIGVIPIKEALKMAEDKHLDLVNVAPNAKPPVCKILD
YGKYKYDALKKEKEAKKNQKVINVKEIRLSPNIEKHDLEVKANQASKFLSNENRVKVSVRFRGRELGHKDLGKEVLDKFY
ELTKDVGQIEKKPSMEGRMMIMFMGPLTDKDN
>Mature_192_residues
MIINFWRVSLPAIIFLEVNNIKDLMINEEIRSSKVRLIDDEGEQIGVIPIKEALKMAEDKHLDLVNVAPNAKPPVCKILD
YGKYKYDALKKEKEAKKNQKVINVKEIRLSPNIEKHDLEVKANQASKFLSNENRVKVSVRFRGRELGHKDLGKEVLDKFY
ELTKDVGQIEKKPSMEGRMMIMFMGPLTDKDN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=162, Percent_Identity=45.679012345679, Blast_Score=143, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22150; Mature: 22150

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINFWRVSLPAIIFLEVNNIKDLMINEEIRSSKVRLIDDEGEQIGVIPIKEALKMAEDK
CEEEEEECCCCEEEEEEECCCHHHEECCHHHCCCEEEEECCCCEEEEEEHHHHHHHHCCC
HLDLVNVAPNAKPPVCKILDYGKYKYDALKKEKEAKKNQKVINVKEIRLSPNIEKHDLEV
CCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEE
KANQASKFLSNENRVKVSVRFRGRELGHKDLGKEVLDKFYELTKDVGQIEKKPSMEGRMM
EHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IMFMGPLTDKDN
EEEECCCCCCCC
>Mature Secondary Structure
MIINFWRVSLPAIIFLEVNNIKDLMINEEIRSSKVRLIDDEGEQIGVIPIKEALKMAEDK
CEEEEEECCCCEEEEEEECCCHHHEECCHHHCCCEEEEECCCCEEEEEEHHHHHHHHCCC
HLDLVNVAPNAKPPVCKILDYGKYKYDALKKEKEAKKNQKVINVKEIRLSPNIEKHDLEV
CCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEE
KANQASKFLSNENRVKVSVRFRGRELGHKDLGKEVLDKFYELTKDVGQIEKKPSMEGRMM
EHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IMFMGPLTDKDN
EEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]