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The map label for this gene is mprF [H]

Identifier: 169824391

GI number: 169824391

Start: 758933

End: 761335

Strand: Direct

Name: mprF [H]

Synonym: FMG_0694

Alternate gene names: 169824391

Gene position: 758933-761335 (Clockwise)

Preceding gene: 169824390

Following gene: 169824392

Centisome position: 42.22

GC content: 25.43

Gene sequence:

>2403_bases
ATGGATAAAAAACTAAAATACATTAGGACATTTTACACAATCATATTTACTATTATAGTGTTGTATATAGTTAGAAATAA
CTTTATTTTGCCAAGTCATATCTTTAAATATAAAATTTTCTTGAGCATGGAACAAAAAATTGAAAATCTAGTACTTGGAA
TACTTGTATTTTTTGTTTCATCTATTTCTTATTTTGTAGTTGATGAGAAATTTAACATTAAAAATTTAAAAAATTACTGG
GCTCTAGAATCACTTAGAAAATTTATATGGATTAATGAGGTGGAATCAGTATTTAAAGAAGCAGACACCTACCAAAATAA
AAAAATAAACAAGAGTATTTCTAATTTTATATCATTATCACTTATAAGTTTATTTACTATATTTTACATTAAGCCTGAAT
GGACTTTGTTTCTAATCTATTTATTTGTAATAGTTATTGCTGTATGTGTAATCTATTTTAAAAACAAATCACTATATTTT
CTAGAGTATATTAGCATTGAGGATATAGGTTTTAAGAGAAAAATTTTATCGACATTATATGAGTTGATAGTTACAATTTG
CAATATTATGTTTTTTGTATTTGTGATAAAACAATTTACTGACGTAAATTTTTCAAATTTAGTGCTGATTTATTGCGTTT
CAAATGTTTTCGGTCAAATTAGTTTGATGCAAGATGGACTGGTAGTATCAGATTTATTACAAATTCATTTATTAAGCAAA
TTGATAGAACCTCGTGCTGCGATTATTGCTATTTTAATGTATAGAATGGTAAGTAGTGTTATACCTTGGATAATTTCATT
AATTATGATTTTGCGAAGAATATATGATAACTACAATACTGATCAACACAAAAAGCAATTTGCGTTCAATATTTTATCAA
TTTTCACACTTATAGTTGGTATAATATTATGTTTAAGCGTTGCGACCCCATCAATTTTATTAAGAATTAAATTTTTAAGG
AGATTCGTCAAGAAAGATGTATTGGTTTTGGCAAGATTTATAACTCTAACATCCGGTGGATTATTAATTTTGCTTTCACA
AGGGATAAAAAAATCGGTGAAAAAATCTTTTTATATAGCTGAAACTGTATTAATTATTTCAGTTTTTTCAACTTTACTAA
AAGGACTAGACATAGAAGAATCAATTATTACATTAATATTGGGCATTGTAATGTATATAATGAAAGATGGATTCACTGAA
AAAGCAATAAAATTCAGAACAAAGTATTTTGCAAATACAATAATAAAATTATCGGCTGTCACAGTATTTTTCATATTCAT
TAGCAATAGTGTTCGCAAAGTAAACTTTTTGAGTTCACATAGAAAGTATTCTTTACATTATTTAGTTGAGAATAAAAAAT
TCATATTATTATATGTTTTATTTGTATTGATATTGTCTTATCTCGCTCAATATACAAGAACAAAAAAGATAACATTTAGT
AAATTGACAGATGAAGATTTCTCTAAAATCGGTAAATTCTTAGGCGAATATGGAGGAAATGAGTTTAGTCATCTTGTTTA
TCTGAATGATAAAAATGTGTATTTTGACAAGACAAATACTGTAATGATAATGTATCGCCCAGTGCAAAACAGCGTTATAG
TATTGGGAGACCCAATTGGAAAGAAAGAAAACTTTGTTGAAGCTATTAATGATTTTATAATTTATTGTAACGAATATCAC
ATGAATGTATGTTTTTATGAAATAAATGGAGAAAATCTAGAATTATATTGCGATCAAGGATTTCGATTTGTAAAAGTTGG
TCAAGATGCAACATTAAACTTAAATGAATTTTCTTTAGTTGGAAAGAAAAATAGAACATGGAGACATGTTATCAATAATT
TTGATAAAGGAAATTATGAGTTTAAAGTTGAAGAGGCAACAGATAATCTTTTATCGCAAATGAAGGTTGTTTCAGATAAA
TGGCTTGGAAATAAAAATGAAATGGGTTTTAGTTTAGGATTTTTTGATGAAGACTATCTAAAAAGAACAAAAATTGCATG
TATATATAAAGGCAATGAGTTACTTGCTTTTGCAAATCTTCAACCTTTTTACGATAACAAAACATTATCAATAGATTTAA
TGAGATATGATAGATCAAATGAAGATGGTTTGATGGATTTCATATTTATCAAGTTGATTTTGTGGGGTCAAGATAATAAT
TTTGAAAAATTTTATCTAGGTATGGCACCTTTATCTAAAGTTGGAGATAAGATTTATTCAAAGAAAAAAGAAAAGATTTT
AAATATTGTTTACAATACTCAAAACAAGATATATAATTTTAAAGGCTTAAGAAACTATAAAGATAAATTTAAGCCTGATT
GGTCAAATAAGTATATAGCATATACTTCAGACTTTAATTTACCATATATTTTAATTAATGTTGTAAATTCTAAGAAAAAA
TAG

Upstream 100 bases:

>100_bases
TGGTAAAATAATTGAAAGCGGAACTCATGACGAGTTATTAGAAAAAGACGGATTTTATAAACAAATGTACGATGAACAAT
CAGCAAATTAAGGGGGATTA

Downstream 100 bases:

>100_bases
TTGACAAAGTGCTCATCATGGTATACAATATTTGTTGTTGATAAGTAGAGGTATCCGCTCTCACCTTATAATTTCGAATT
CATAAGGTTAAAATTTAATT

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 800; Mature: 800

Protein sequence:

>800_residues
MDKKLKYIRTFYTIIFTIIVLYIVRNNFILPSHIFKYKIFLSMEQKIENLVLGILVFFVSSISYFVVDEKFNIKNLKNYW
ALESLRKFIWINEVESVFKEADTYQNKKINKSISNFISLSLISLFTIFYIKPEWTLFLIYLFVIVIAVCVIYFKNKSLYF
LEYISIEDIGFKRKILSTLYELIVTICNIMFFVFVIKQFTDVNFSNLVLIYCVSNVFGQISLMQDGLVVSDLLQIHLLSK
LIEPRAAIIAILMYRMVSSVIPWIISLIMILRRIYDNYNTDQHKKQFAFNILSIFTLIVGIILCLSVATPSILLRIKFLR
RFVKKDVLVLARFITLTSGGLLILLSQGIKKSVKKSFYIAETVLIISVFSTLLKGLDIEESIITLILGIVMYIMKDGFTE
KAIKFRTKYFANTIIKLSAVTVFFIFISNSVRKVNFLSSHRKYSLHYLVENKKFILLYVLFVLILSYLAQYTRTKKITFS
KLTDEDFSKIGKFLGEYGGNEFSHLVYLNDKNVYFDKTNTVMIMYRPVQNSVIVLGDPIGKKENFVEAINDFIIYCNEYH
MNVCFYEINGENLELYCDQGFRFVKVGQDATLNLNEFSLVGKKNRTWRHVINNFDKGNYEFKVEEATDNLLSQMKVVSDK
WLGNKNEMGFSLGFFDEDYLKRTKIACIYKGNELLAFANLQPFYDNKTLSIDLMRYDRSNEDGLMDFIFIKLILWGQDNN
FEKFYLGMAPLSKVGDKIYSKKKEKILNIVYNTQNKIYNFKGLRNYKDKFKPDWSNKYIAYTSDFNLPYILINVVNSKKK

Sequences:

>Translated_800_residues
MDKKLKYIRTFYTIIFTIIVLYIVRNNFILPSHIFKYKIFLSMEQKIENLVLGILVFFVSSISYFVVDEKFNIKNLKNYW
ALESLRKFIWINEVESVFKEADTYQNKKINKSISNFISLSLISLFTIFYIKPEWTLFLIYLFVIVIAVCVIYFKNKSLYF
LEYISIEDIGFKRKILSTLYELIVTICNIMFFVFVIKQFTDVNFSNLVLIYCVSNVFGQISLMQDGLVVSDLLQIHLLSK
LIEPRAAIIAILMYRMVSSVIPWIISLIMILRRIYDNYNTDQHKKQFAFNILSIFTLIVGIILCLSVATPSILLRIKFLR
RFVKKDVLVLARFITLTSGGLLILLSQGIKKSVKKSFYIAETVLIISVFSTLLKGLDIEESIITLILGIVMYIMKDGFTE
KAIKFRTKYFANTIIKLSAVTVFFIFISNSVRKVNFLSSHRKYSLHYLVENKKFILLYVLFVLILSYLAQYTRTKKITFS
KLTDEDFSKIGKFLGEYGGNEFSHLVYLNDKNVYFDKTNTVMIMYRPVQNSVIVLGDPIGKKENFVEAINDFIIYCNEYH
MNVCFYEINGENLELYCDQGFRFVKVGQDATLNLNEFSLVGKKNRTWRHVINNFDKGNYEFKVEEATDNLLSQMKVVSDK
WLGNKNEMGFSLGFFDEDYLKRTKIACIYKGNELLAFANLQPFYDNKTLSIDLMRYDRSNEDGLMDFIFIKLILWGQDNN
FEKFYLGMAPLSKVGDKIYSKKKEKILNIVYNTQNKIYNFKGLRNYKDKFKPDWSNKYIAYTSDFNLPYILINVVNSKKK
>Mature_800_residues
MDKKLKYIRTFYTIIFTIIVLYIVRNNFILPSHIFKYKIFLSMEQKIENLVLGILVFFVSSISYFVVDEKFNIKNLKNYW
ALESLRKFIWINEVESVFKEADTYQNKKINKSISNFISLSLISLFTIFYIKPEWTLFLIYLFVIVIAVCVIYFKNKSLYF
LEYISIEDIGFKRKILSTLYELIVTICNIMFFVFVIKQFTDVNFSNLVLIYCVSNVFGQISLMQDGLVVSDLLQIHLLSK
LIEPRAAIIAILMYRMVSSVIPWIISLIMILRRIYDNYNTDQHKKQFAFNILSIFTLIVGIILCLSVATPSILLRIKFLR
RFVKKDVLVLARFITLTSGGLLILLSQGIKKSVKKSFYIAETVLIISVFSTLLKGLDIEESIITLILGIVMYIMKDGFTE
KAIKFRTKYFANTIIKLSAVTVFFIFISNSVRKVNFLSSHRKYSLHYLVENKKFILLYVLFVLILSYLAQYTRTKKITFS
KLTDEDFSKIGKFLGEYGGNEFSHLVYLNDKNVYFDKTNTVMIMYRPVQNSVIVLGDPIGKKENFVEAINDFIIYCNEYH
MNVCFYEINGENLELYCDQGFRFVKVGQDATLNLNEFSLVGKKNRTWRHVINNFDKGNYEFKVEEATDNLLSQMKVVSDK
WLGNKNEMGFSLGFFDEDYLKRTKIACIYKGNELLAFANLQPFYDNKTLSIDLMRYDRSNEDGLMDFIFIKLILWGQDNN
FEKFYLGMAPLSKVGDKIYSKKKEKILNIVYNTQNKIYNFKGLRNYKDKFKPDWSNKYIAYTSDFNLPYILINVVNSKKK

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 93770; Mature: 93770

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKLKYIRTFYTIIFTIIVLYIVRNNFILPSHIFKYKIFLSMEQKIENLVLGILVFFVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHH
SISYFVVDEKFNIKNLKNYWALESLRKFIWINEVESVFKEADTYQNKKINKSISNFISLS
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LISLFTIFYIKPEWTLFLIYLFVIVIAVCVIYFKNKSLYFLEYISIEDIGFKRKILSTLY
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHH
ELIVTICNIMFFVFVIKQFTDVNFSNLVLIYCVSNVFGQISLMQDGLVVSDLLQIHLLSK
HHHHHHHHHHHHHHHHHHHCCCCHHHEEHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LIEPRAAIIAILMYRMVSSVIPWIISLIMILRRIYDNYNTDQHKKQFAFNILSIFTLIVG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IILCLSVATPSILLRIKFLRRFVKKDVLVLARFITLTSGGLLILLSQGIKKSVKKSFYIA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
ETVLIISVFSTLLKGLDIEESIITLILGIVMYIMKDGFTEKAIKFRTKYFANTIIKLSAV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
TVFFIFISNSVRKVNFLSSHRKYSLHYLVENKKFILLYVLFVLILSYLAQYTRTKKITFS
HHHHHHHHCCCCEEHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEH
KLTDEDFSKIGKFLGEYGGNEFSHLVYLNDKNVYFDKTNTVMIMYRPVQNSVIVLGDPIG
HCCHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCCEEEEEEEECCCCEEEEECCCC
KKENFVEAINDFIIYCNEYHMNVCFYEINGENLELYCDQGFRFVKVGQDATLNLNEFSLV
CCHHHHHHHHHHEEEEEEEEEEEEEEEECCCCEEEEECCCCEEEEECCCCEECCCCEEEE
GKKNRTWRHVINNFDKGNYEFKVEEATDNLLSQMKVVSDKWLGNKNEMGFSLGFFDEDYL
CCCCCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHH
KRTKIACIYKGNELLAFANLQPFYDNKTLSIDLMRYDRSNEDGLMDFIFIKLILWGQDNN
HHCEEEEEEECCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHEECCCCC
FEKFYLGMAPLSKVGDKIYSKKKEKILNIVYNTQNKIYNFKGLRNYKDKFKPDWSNKYIA
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCCEEE
YTSDFNLPYILINVVNSKKK
EEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MDKKLKYIRTFYTIIFTIIVLYIVRNNFILPSHIFKYKIFLSMEQKIENLVLGILVFFVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHH
SISYFVVDEKFNIKNLKNYWALESLRKFIWINEVESVFKEADTYQNKKINKSISNFISLS
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LISLFTIFYIKPEWTLFLIYLFVIVIAVCVIYFKNKSLYFLEYISIEDIGFKRKILSTLY
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHH
ELIVTICNIMFFVFVIKQFTDVNFSNLVLIYCVSNVFGQISLMQDGLVVSDLLQIHLLSK
HHHHHHHHHHHHHHHHHHHCCCCHHHEEHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LIEPRAAIIAILMYRMVSSVIPWIISLIMILRRIYDNYNTDQHKKQFAFNILSIFTLIVG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IILCLSVATPSILLRIKFLRRFVKKDVLVLARFITLTSGGLLILLSQGIKKSVKKSFYIA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
ETVLIISVFSTLLKGLDIEESIITLILGIVMYIMKDGFTEKAIKFRTKYFANTIIKLSAV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
TVFFIFISNSVRKVNFLSSHRKYSLHYLVENKKFILLYVLFVLILSYLAQYTRTKKITFS
HHHHHHHHCCCCEEHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEH
KLTDEDFSKIGKFLGEYGGNEFSHLVYLNDKNVYFDKTNTVMIMYRPVQNSVIVLGDPIG
HCCHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCCEEEEEEEECCCCEEEEECCCC
KKENFVEAINDFIIYCNEYHMNVCFYEINGENLELYCDQGFRFVKVGQDATLNLNEFSLV
CCHHHHHHHHHHEEEEEEEEEEEEEEEECCCCEEEEECCCCEEEEECCCCEECCCCEEEE
GKKNRTWRHVINNFDKGNYEFKVEEATDNLLSQMKVVSDKWLGNKNEMGFSLGFFDEDYL
CCCCCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHH
KRTKIACIYKGNELLAFANLQPFYDNKTLSIDLMRYDRSNEDGLMDFIFIKLILWGQDNN
HHCEEEEEEECCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHEECCCCC
FEKFYLGMAPLSKVGDKIYSKKKEKILNIVYNTQNKIYNFKGLRNYKDKFKPDWSNKYIA
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCCEEE
YTSDFNLPYILINVVNSKKK
EEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]