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The map label for this gene is coaD

Identifier: 169824374

GI number: 169824374

Start: 740586

End: 741074

Strand: Direct

Name: coaD

Synonym: FMG_0677

Alternate gene names: 169824374

Gene position: 740586-741074 (Clockwise)

Preceding gene: 169824373

Following gene: 169824375

Centisome position: 41.2

GC content: 30.88

Gene sequence:

>489_bases
ATGAATAAAACAAAAGTTTTATATCCAGGTAGTTTTGATCCGATAACAAATGGGCACATGGATATCATTGAAAGAAGCGC
AAAGATTTTTGAAGAAGTAAATGTAGCTGTTGTAAAAAATATTCAAAAGAAAAGTACATTTACGCTAGAACAGAGAGTTG
AAATGATTGAAAAAGCTTGTAAACATTTATCTAATGTAAAGATCCATCAATTTGAAGGATTGACTGTAGATTTTGCAAAA
CAAATAGGATGTAGTACAATTATAAGGGGACTACGTGCTGTAAGTGATTTTGAGTCAGAAATGCAAATGTCATTGGCTAA
TAAAAAGTTAAATGATGAATTAGAAACATTATTTCTAGTTGCAGATGGAAAGTATGCATTTCTTTCGTCTTCTATAGTAA
GGGAGATAGCTTCATATGGCGCTGATATCTCAGAACTTGTTCCAGAAAATATCGTTGAGGATATAAAGCAAAGATTTAAC
GATAAATAA

Upstream 100 bases:

>100_bases
TCAGAAAAAGAGTTGCCAGATGAATATTTTGGTTCTTTGAATTTGGAAAAGCAAAAACAATATGGAAAAAAGAAAAATAT
TTATTTTTTGAGGAAAGATA

Downstream 100 bases:

>100_bases
ACGCTTTATCTTGAATTAATTTGATATTTTTATTATAATAATTATAAGAATAATTAGCTCAATGCGGGAGGGTTACATGG
ATATTATTAAATTAATAGAA

Product: putative phosphopantetheine adenyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MNKTKVLYPGSFDPITNGHMDIIERSAKIFEEVNVAVVKNIQKKSTFTLEQRVEMIEKACKHLSNVKIHQFEGLTVDFAK
QIGCSTIIRGLRAVSDFESEMQMSLANKKLNDELETLFLVADGKYAFLSSSIVREIASYGADISELVPENIVEDIKQRFN
DK

Sequences:

>Translated_162_residues
MNKTKVLYPGSFDPITNGHMDIIERSAKIFEEVNVAVVKNIQKKSTFTLEQRVEMIEKACKHLSNVKIHQFEGLTVDFAK
QIGCSTIIRGLRAVSDFESEMQMSLANKKLNDELETLFLVADGKYAFLSSSIVREIASYGADISELVPENIVEDIKQRFN
DK
>Mature_162_residues
MNKTKVLYPGSFDPITNGHMDIIERSAKIFEEVNVAVVKNIQKKSTFTLEQRVEMIEKACKHLSNVKIHQFEGLTVDFAK
QIGCSTIIRGLRAVSDFESEMQMSLANKKLNDELETLFLVADGKYAFLSSSIVREIASYGADISELVPENIVEDIKQRFN
DK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=149, Percent_Identity=43.6241610738255, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_FINM2 (B0S155)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001691985.1
- ProteinModelPortal:   B0S155
- SMR:   B0S155
- GeneID:   6019655
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_0677
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- BioCyc:   FMAG334413:FMG_0677-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18319; Mature: 18319

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTKVLYPGSFDPITNGHMDIIERSAKIFEEVNVAVVKNIQKKSTFTLEQRVEMIEKAC
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KHLSNVKIHQFEGLTVDFAKQIGCSTIIRGLRAVSDFESEMQMSLANKKLNDELETLFLV
HHHHCCCEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
ADGKYAFLSSSIVREIASYGADISELVPENIVEDIKQRFNDK
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKTKVLYPGSFDPITNGHMDIIERSAKIFEEVNVAVVKNIQKKSTFTLEQRVEMIEKAC
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KHLSNVKIHQFEGLTVDFAKQIGCSTIIRGLRAVSDFESEMQMSLANKKLNDELETLFLV
HHHHCCCEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
ADGKYAFLSSSIVREIASYGADISELVPENIVEDIKQRFNDK
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA