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The map label for this gene is prpC [H]

Identifier: 169824363

GI number: 169824363

Start: 730166

End: 730903

Strand: Direct

Name: prpC [H]

Synonym: FMG_0666

Alternate gene names: 169824363

Gene position: 730166-730903 (Clockwise)

Preceding gene: 169824362

Following gene: 169824364

Centisome position: 40.62

GC content: 29.95

Gene sequence:

>738_bases
ATGAAATATGCTTCAAACACAGACATCGGCTTGGTAAGAAAGCTAAATGAAGATTATCATATGAATTATATGACTGATGA
TTTTAGCTTACTTGTTGTATGTGATGGAATGGGCGGACATAAAGCTGGTGAAGTTGCAAGTAAGAAGGCAGTCGAAACAG
TTGTAAATTTTGTAAAAGAAAATGAAAATGAGAAAGATTATGAGAGAATATTAACTGAGGCTATTGAATTAGCTAACGAT
GAAGTATTCAACGATAGTGAAAATAATTCGGAACATAGAAACATGGGAACTACGATAGTTGCATGCTTAATTCATGATGA
TAATGCTATTGTAGCAAATGTAGGTGATAGTAGATTATACTTGTATAGAGATGAAGAATTAAAGCAAATAACTGTCGATC
ATTCTCTTGTAAATGACTTGTTATCATCTGGAACTATCACAGAAGAAGAAGCTGTTGATTTCGCGCAAAAAAATGTTATT
ACAAGATCATTGGGAATTCAAGATAATGTAGATGTAGATATATTTAATATTAAACTTGTTAATGGAGATTTGATATTAAT
GTGTACAGATGGATTAACTTCACAATTAGAAAATGAAGACATAGTTGATATTATCAAAGAAGAATCGGATTTAGATCAAA
TTATTAAAAATTTGATTGATGAAGCAAATGATATCGAAGGAATAGATAATGTAACTATTACGCTTTATTTATTTGAAGGG
GAAAATTATGATAGGTAA

Upstream 100 bases:

>100_bases
AAAATAATGTGAATACAACGATAAGAAGAAAACAAGGCATTGATATAGATGGGGCCTGTGGACAATTAAGAATTAACAAT
ATGACAAAAAGAGGTGTGAA

Downstream 100 bases:

>100_bases
AATTTTAGGCGATAGATACGAGATAATAGAAGAAGTCGGCGTTGGAGGTATGGCCAAAGTGTACAAAGCTTTGGATACTG
TTTTAAATCGATATGTCGCT

Product: serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKYASNTDIGLVRKLNEDYHMNYMTDDFSLLVVCDGMGGHKAGEVASKKAVETVVNFVKENENEKDYERILTEAIELAND
EVFNDSENNSEHRNMGTTIVACLIHDDNAIVANVGDSRLYLYRDEELKQITVDHSLVNDLLSSGTITEEEAVDFAQKNVI
TRSLGIQDNVDVDIFNIKLVNGDLILMCTDGLTSQLENEDIVDIIKEESDLDQIIKNLIDEANDIEGIDNVTITLYLFEG
ENYDR

Sequences:

>Translated_245_residues
MKYASNTDIGLVRKLNEDYHMNYMTDDFSLLVVCDGMGGHKAGEVASKKAVETVVNFVKENENEKDYERILTEAIELAND
EVFNDSENNSEHRNMGTTIVACLIHDDNAIVANVGDSRLYLYRDEELKQITVDHSLVNDLLSSGTITEEEAVDFAQKNVI
TRSLGIQDNVDVDIFNIKLVNGDLILMCTDGLTSQLENEDIVDIIKEESDLDQIIKNLIDEANDIEGIDNVTITLYLFEG
ENYDR
>Mature_245_residues
MKYASNTDIGLVRKLNEDYHMNYMTDDFSLLVVCDGMGGHKAGEVASKKAVETVVNFVKENENEKDYERILTEAIELAND
EVFNDSENNSEHRNMGTTIVACLIHDDNAIVANVGDSRLYLYRDEELKQITVDHSLVNDLLSSGTITEEEAVDFAQKNVI
TRSLGIQDNVDVDIFNIKLVNGDLILMCTDGLTSQLENEDIVDIIKEESDLDQIIKNLIDEANDIEGIDNVTITLYLFEG
ENYDR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27565; Mature: 27565

Theoretical pI: Translated: 3.92; Mature: 3.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYASNTDIGLVRKLNEDYHMNYMTDDFSLLVVCDGMGGHKAGEVASKKAVETVVNFVKE
CCCCCCCCHHHHHHCCCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
NENEKDYERILTEAIELANDEVFNDSENNSEHRNMGTTIVACLIHDDNAIVANVGDSRLY
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEEEECCCEEEEECCCCEEE
LYRDEELKQITVDHSLVNDLLSSGTITEEEAVDFAQKNVITRSLGIQDNVDVDIFNIKLV
EEECCCHHEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEE
NGDLILMCTDGLTSQLENEDIVDIIKEESDLDQIIKNLIDEANDIEGIDNVTITLYLFEG
CCCEEEEECCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEC
ENYDR
CCCCC
>Mature Secondary Structure
MKYASNTDIGLVRKLNEDYHMNYMTDDFSLLVVCDGMGGHKAGEVASKKAVETVVNFVKE
CCCCCCCCHHHHHHCCCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
NENEKDYERILTEAIELANDEVFNDSENNSEHRNMGTTIVACLIHDDNAIVANVGDSRLY
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEEEECCCEEEEECCCCEEE
LYRDEELKQITVDHSLVNDLLSSGTITEEEAVDFAQKNVITRSLGIQDNVDVDIFNIKLV
EEECCCHHEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEE
NGDLILMCTDGLTSQLENEDIVDIIKEESDLDQIIKNLIDEANDIEGIDNVTITLYLFEG
CCCEEEEECCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEC
ENYDR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]