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The map label for this gene is argC

Identifier: 167625998

GI number: 167625998

Start: 4980818

End: 4981810

Strand: Reverse

Name: argC

Synonym: Shal_4093

Alternate gene names: 167625998

Gene position: 4981810-4980818 (Counterclockwise)

Preceding gene: 167626002

Following gene: 167625997

Centisome position: 95.31

GC content: 47.83

Gene sequence:

>993_bases
ATGAAAAATATAGCCATTATTGGTGCCAGTGGTTACACCGGCGCACAGATCTCCTCTCTTATAAATGCCGAATCGACGAT
GTCGATCCAGGGGCTTTATGTCTCTGAAAACAGCCTCGACAAGGGCAAGGCTCTATCTGATCTTTATCCTGCTTACAGTC
ATATAGACTTGTGCTTAACCCCCCTTACCGATGATGCGAAGCAAACTATCGTAGCGACTGCCGATGCGGTGGTACTCGCG
ACTGATCACGGGGTGAGCTTACATCTCGCTGCGTGGTTTTATCAGCAAGGATTGGCGGTATTTGATTTAAGCGGTGCATA
TCGGTTTTCCGATGTTGCTCAGTATCCTAAGTGGTATGGTTTTACTCACGAATATTCCCAAGTACTGGCTGACGCCGTAT
ATGGCTTAGCGGAGTGGAATGCGCCGCAAATCGCGACGAGTAAGATGATTGCGGTACCGGGTTGTTATCCAACGGCCTCA
CTGATAGCGCTTAAACCTGTTGCACATTTACTCACCGATATATTGCCAGTGATTAATGCAGTCAGCGGCGTAACTGGAGC
GGGCAGAAAAGCGCAGCTGCATACCAGTTTTTGTGAAGTCAGTTTGACCCCCTACGGCGTACTTGGTCACAGGCACCAGC
CTGAGATTGCCACTCAGCTAGGACAAGAGGTGATCTTCACGCCTCACCTCGGTAATTTTAAACGCGGCATTCTTGCAACC
ATCACAGTGCAATTAGCTGCGGGTACGACAGCCAGCGATATTGAAAAAGCATACCAATGTTACGACTCTGCCGAGCTTAT
CACTGTAAAACAAAATCAATTCCCTAAGGTGGATGATGTGGTGCAAACAGCTAATTGTCATCTGGGGTGGAAGTTCGATG
AACAGAGTGGCTATCTGGTCATCGCTAGCGCGATTGATAACTTAATGAAAGGGGCGGCTAGTCAAGCGCTGCAGTGCATA
AAGATTCATTTTAATGCATCTGTAAATCACTAG

Upstream 100 bases:

>100_bases
ATCTTGTCATTAATGGTGTTCAGCCAGGGCTTAAGTTGTGCCCATTCTTTTTTGCGTTTTGTCATCTAAATTCAAGATTA
AGGTTTTAAAGTCATAGACT

Downstream 100 bases:

>100_bases
GTGGGTAAGAATATGACTGATACGCAGATGGCTAATACACGAGCGATAAGCTCAGGCGCTAAGCCTGTCATGGTGCTCAA
AGTTGGCGGTGCATTACTGC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKNIAIIGASGYTGAQISSLINAESTMSIQGLYVSENSLDKGKALSDLYPAYSHIDLCLTPLTDDAKQTIVATADAVVLA
TDHGVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYGFTHEYSQVLADAVYGLAEWNAPQIATSKMIAVPGCYPTAS
LIALKPVAHLLTDILPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
ITVQLAAGTTASDIEKAYQCYDSAELITVKQNQFPKVDDVVQTANCHLGWKFDEQSGYLVIASAIDNLMKGAASQALQCI
KIHFNASVNH

Sequences:

>Translated_330_residues
MKNIAIIGASGYTGAQISSLINAESTMSIQGLYVSENSLDKGKALSDLYPAYSHIDLCLTPLTDDAKQTIVATADAVVLA
TDHGVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYGFTHEYSQVLADAVYGLAEWNAPQIATSKMIAVPGCYPTAS
LIALKPVAHLLTDILPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
ITVQLAAGTTASDIEKAYQCYDSAELITVKQNQFPKVDDVVQTANCHLGWKFDEQSGYLVIASAIDNLMKGAASQALQCI
KIHFNASVNH
>Mature_330_residues
MKNIAIIGASGYTGAQISSLINAESTMSIQGLYVSENSLDKGKALSDLYPAYSHIDLCLTPLTDDAKQTIVATADAVVLA
TDHGVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYGFTHEYSQVLADAVYGLAEWNAPQIATSKMIAVPGCYPTAS
LIALKPVAHLLTDILPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
ITVQLAAGTTASDIEKAYQCYDSAELITVKQNQFPKVDDVVQTANCHLGWKFDEQSGYLVIASAIDNLMKGAASQALQCI
KIHFNASVNH

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=329, Percent_Identity=50.4559270516717, Blast_Score=295, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6320913, Length=341, Percent_Identity=29.9120234604106, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_SHEHH (B0TL88)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001676292.1
- ProteinModelPortal:   B0TL88
- SMR:   B0TL88
- GeneID:   5903380
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_4093
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   SHAL458817:SHAL_4093-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 35465; Mature: 35465

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIAIIGASGYTGAQISSLINAESTMSIQGLYVSENSLDKGKALSDLYPAYSHIDLCLT
CCCEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHCCCHHCCEEEEE
PLTDDAKQTIVATADAVVLATDHGVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYG
CCCCCHHHEEEEECCEEEEEECCCCEEHHHHHHHHCCCEEEECCCCCCHHHHHHCHHHCC
FTHEYSQVLADAVYGLAEWNAPQIATSKMIAVPGCYPTASLIALKPVAHLLTDILPVINA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
HCCCCCCCCCEEEEEHEEEEECCCEEECCCCCCCHHHHHCCCEEEECCCCCCCCCCEEEE
ITVQLAAGTTASDIEKAYQCYDSAELITVKQNQFPKVDDVVQTANCHLGWKFDEQSGYLV
EEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCEEEEEEECCCCEEE
IASAIDNLMKGAASQALQCIKIHFNASVNH
EHHHHHHHHHHHHHHHEEEEEEEEECCCCC
>Mature Secondary Structure
MKNIAIIGASGYTGAQISSLINAESTMSIQGLYVSENSLDKGKALSDLYPAYSHIDLCLT
CCCEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHCCCHHCCEEEEE
PLTDDAKQTIVATADAVVLATDHGVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYG
CCCCCHHHEEEEECCEEEEEECCCCEEHHHHHHHHCCCEEEECCCCCCHHHHHHCHHHCC
FTHEYSQVLADAVYGLAEWNAPQIATSKMIAVPGCYPTASLIALKPVAHLLTDILPVINA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
HCCCCCCCCCEEEEEHEEEEECCCEEECCCCCCCHHHHHCCCEEEECCCCCCCCCCEEEE
ITVQLAAGTTASDIEKAYQCYDSAELITVKQNQFPKVDDVVQTANCHLGWKFDEQSGYLV
EEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCEEEEEEECCCCEEE
IASAIDNLMKGAASQALQCIKIHFNASVNH
EHHHHHHHHHHHHHHHEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA