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The map label for this gene is cinA [C]

Identifier: 167626002

GI number: 167626002

Start: 4986662

End: 4987936

Strand: Reverse

Name: cinA [C]

Synonym: Shal_4097

Alternate gene names: 167626002

Gene position: 4987936-4986662 (Counterclockwise)

Preceding gene: 167626003

Following gene: 167625998

Centisome position: 95.43

GC content: 43.92

Gene sequence:

>1275_bases
ATGAAGCTGGAAATGATTTGTACTGGTGAAGAGGTATTGGCTGGTCAAATAGTCGATACCAATGCTGCATGGTTTGCTAA
CACTATGATGGATCAAGGGATTGAATGTCAGCGTCGAGTCACGGTAGGTGATCGGCTAGAAGATCTTATCTCTGTATTTA
GAGAACGTAGCCTAGAAGCTGATATTATTTTAGTTAATGGGGGTCTTGGGCCGACGAGTGACGATCTCTCAACTGAAGCG
ATGGCTTTAGCAAAGGGTGAGACTCTAGTTGAAAATAGTATTTGGCGTCAACGTCTAGAAGACTGGTTTGCCCGAAGTGG
TCGTGTTATGGCTGAGAGTAACCTTAAGCAAGCTCTATTGCCTGAATCAGCTATTATGATAGACAATCCTGTCGGCACGG
CCTGTGGCTTTGCAGTTAAGTTTAATCGGGCTTGGCTGTTCTTTACTCCTGGGGTTCCATTTGAATTTAAACAGATGGTT
CATGAGCAGTTTATTCCATTTGTTAAGCAGCGTTTTGACGTAAGTGGTGATGTTGCATTAAGAAAGTACCTGACCCTTGG
CCAAGGTGAATCTTCACTTGCGGATACTTTAGATAAAATAGAACTGCCAGAGGGGATGACTATAGGCTATCGGTCTTCGA
TGCCGCATATCGAGATTAAACTCTTTGCCCGTGGCATTGGCGCAATCGATCAACTTGATACGATTGAAACGCAGATCCGC
CTTTTACTGGGTAATGCCATTGTTGCCGATAATAAGATGAGTTTGGCTGAAGAGATCCACGCTCTATTAGTCGACTCAGA
TCTTAGTTTAAGTGTGGCGGAATCATGTACTGGCGGCATGATTGTGAGTCAGCTAATTAGTTTTTCTGGTAGCTCATCAT
ATTTACACCAAGGCTTAGTGACTTATTGTAATGAATCTAAAGTAAAAGTATTGGGTGTTAAACCTGAAACCTTAGATGTT
CACGGTGCTGTTTCCATCGCTACAGTAGAGGAGATGGCAAAAGGAGCTAGAGCCATATTAGATAGTGACTTTGGGTTAGC
GACTAGTGGTATTGCTGGGCCAACGGGGGGCACTGATAACAAACCTGTTGGTACTGTTGCTATTGCTCTCGCAACCAAAG
AAGGCGTTTACAGCCAGATGATCAAGCTTCCAAGGCGCTCTCGTGATCTGGTGCGTAGCTTAAGTACAGCCGTAGCGTTC
GATATGCTAAGAAGAGAGTTATTAGGCCAAGCGGTTATTGTCGATTATGGTTCGATAGGCCGTTTTGAAAAATAA

Upstream 100 bases:

>100_bases
ACTGATTGGTATTAATTACAGGAAATAATCACAATTGATTATTGCTATTACAGCTCAGGTTTCATAGTTTAGCTGCAATG
AAGACGCTAAGGACTCGCGA

Downstream 100 bases:

>100_bases
CTCCTGGAAAATAATAAAAAAAGCAGGCTCATAGGAGCCTGCTTTTTTAGTTTTAATAGTGAACTAATTACTTATCGTTA
GTCTTCAAAAACCAATACCA

Product: competence/damage-inducible protein CinA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKLEMICTGEEVLAGQIVDTNAAWFANTMMDQGIECQRRVTVGDRLEDLISVFRERSLEADIILVNGGLGPTSDDLSTEA
MALAKGETLVENSIWRQRLEDWFARSGRVMAESNLKQALLPESAIMIDNPVGTACGFAVKFNRAWLFFTPGVPFEFKQMV
HEQFIPFVKQRFDVSGDVALRKYLTLGQGESSLADTLDKIELPEGMTIGYRSSMPHIEIKLFARGIGAIDQLDTIETQIR
LLLGNAIVADNKMSLAEEIHALLVDSDLSLSVAESCTGGMIVSQLISFSGSSSYLHQGLVTYCNESKVKVLGVKPETLDV
HGAVSIATVEEMAKGARAILDSDFGLATSGIAGPTGGTDNKPVGTVAIALATKEGVYSQMIKLPRRSRDLVRSLSTAVAF
DMLRRELLGQAVIVDYGSIGRFEK

Sequences:

>Translated_424_residues
MKLEMICTGEEVLAGQIVDTNAAWFANTMMDQGIECQRRVTVGDRLEDLISVFRERSLEADIILVNGGLGPTSDDLSTEA
MALAKGETLVENSIWRQRLEDWFARSGRVMAESNLKQALLPESAIMIDNPVGTACGFAVKFNRAWLFFTPGVPFEFKQMV
HEQFIPFVKQRFDVSGDVALRKYLTLGQGESSLADTLDKIELPEGMTIGYRSSMPHIEIKLFARGIGAIDQLDTIETQIR
LLLGNAIVADNKMSLAEEIHALLVDSDLSLSVAESCTGGMIVSQLISFSGSSSYLHQGLVTYCNESKVKVLGVKPETLDV
HGAVSIATVEEMAKGARAILDSDFGLATSGIAGPTGGTDNKPVGTVAIALATKEGVYSQMIKLPRRSRDLVRSLSTAVAF
DMLRRELLGQAVIVDYGSIGRFEK
>Mature_424_residues
MKLEMICTGEEVLAGQIVDTNAAWFANTMMDQGIECQRRVTVGDRLEDLISVFRERSLEADIILVNGGLGPTSDDLSTEA
MALAKGETLVENSIWRQRLEDWFARSGRVMAESNLKQALLPESAIMIDNPVGTACGFAVKFNRAWLFFTPGVPFEFKQMV
HEQFIPFVKQRFDVSGDVALRKYLTLGQGESSLADTLDKIELPEGMTIGYRSSMPHIEIKLFARGIGAIDQLDTIETQIR
LLLGNAIVADNKMSLAEEIHALLVDSDLSLSVAESCTGGMIVSQLISFSGSSSYLHQGLVTYCNESKVKVLGVKPETLDV
HGAVSIATVEEMAKGARAILDSDFGLATSGIAGPTGGTDNKPVGTVAIALATKEGVYSQMIKLPRRSRDLVRSLSTAVAF
DMLRRELLGQAVIVDYGSIGRFEK

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=422, Percent_Identity=40.7582938388626, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1789052, Length=156, Percent_Identity=41.6666666666667, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1787818, Length=151, Percent_Identity=33.7748344370861, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323832, Length=227, Percent_Identity=26.431718061674, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_SHEHH (B0TL92)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001676296.1
- ProteinModelPortal:   B0TL92
- SMR:   B0TL92
- GeneID:   5904237
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_4097
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   CLSK905663
- BioCyc:   SHAL458817:SHAL_4097-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 46093; Mature: 46093

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEMICTGEEVLAGQIVDTNAAWFANTMMDQGIECQRRVTVGDRLEDLISVFRERSLEA
CEEEEEECCCHHHCCEEEECCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCC
DIILVNGGLGPTSDDLSTEAMALAKGETLVENSIWRQRLEDWFARSGRVMAESNLKQALL
CEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHC
PESAIMIDNPVGTACGFAVKFNRAWLFFTPGVPFEFKQMVHEQFIPFVKQRFDVSGDVAL
CCCCEEEECCCCCHHCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
RKYLTLGQGESSLADTLDKIELPEGMTIGYRSSMPHIEIKLFARGIGAIDQLDTIETQIR
HHHHHCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
LLLGNAIVADNKMSLAEEIHALLVDSDLSLSVAESCTGGMIVSQLISFSGSSSYLHQGLV
HHHCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
TYCNESKVKVLGVKPETLDVHGAVSIATVEEMAKGARAILDSDFGLATSGIAGPTGGTDN
HHCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
KPVGTVAIALATKEGVYSQMIKLPRRSRDLVRSLSTAVAFDMLRRELLGQAVIVDYGSIG
CCCCEEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
RFEK
CCCC
>Mature Secondary Structure
MKLEMICTGEEVLAGQIVDTNAAWFANTMMDQGIECQRRVTVGDRLEDLISVFRERSLEA
CEEEEEECCCHHHCCEEEECCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCC
DIILVNGGLGPTSDDLSTEAMALAKGETLVENSIWRQRLEDWFARSGRVMAESNLKQALL
CEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHC
PESAIMIDNPVGTACGFAVKFNRAWLFFTPGVPFEFKQMVHEQFIPFVKQRFDVSGDVAL
CCCCEEEECCCCCHHCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
RKYLTLGQGESSLADTLDKIELPEGMTIGYRSSMPHIEIKLFARGIGAIDQLDTIETQIR
HHHHHCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
LLLGNAIVADNKMSLAEEIHALLVDSDLSLSVAESCTGGMIVSQLISFSGSSSYLHQGLV
HHHCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
TYCNESKVKVLGVKPETLDVHGAVSIATVEEMAKGARAILDSDFGLATSGIAGPTGGTDN
HHCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
KPVGTVAIALATKEGVYSQMIKLPRRSRDLVRSLSTAVAFDMLRRELLGQAVIVDYGSIG
CCCCEEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
RFEK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA