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The map label for this gene is ilvE [H]

Identifier: 167625847

GI number: 167625847

Start: 4807350

End: 4808279

Strand: Reverse

Name: ilvE [H]

Synonym: Shal_3942

Alternate gene names: 167625847

Gene position: 4808279-4807350 (Counterclockwise)

Preceding gene: 167625848

Following gene: 167625846

Centisome position: 91.99

GC content: 50.0

Gene sequence:

>930_bases
ATGGCCGCGAAAACAGCAGAGTTAATTTGGTTCAATGGTGAAATGATGCCTTGGGGTGATGCTAAGGTTCATGTCATGTC
TCACGCGCTGCACTATGGTACTTCCGTTTTTGAAGGCATACGTGTTTACGATACTCATCGCGGTCCGGCGGGGTTTCGTT
TAACTGAGCATATTCAGCGCCTATTTGATTCTGCCAAGATTTACCGTATGCCTATCCCATATAGCTTCGATAATGTTATG
CAGGCGTGTCGAGACGCCACATTAGGCAATGGTTTAAAGAGCGCTTATATCCGCCCCTTAGCCTTTTATGGTGATGTTGG
TATGGGGATCACCCCCCCTAAAGATGCTCAGTGCGACTTGTTAGTCGCAGCATTTCCGTGGGGAGCCTATTTAGGGGAAG
ACAGCATGGATGCCGGGGTCGATGTCGCGGTAACCTCCTGGAATCGCTTAGCGCCAAACACGATTCCAACGGGAGCCAAA
GCGGGCGGGAATTACCTCTCTTCGCTACAGATCTCTACCGAAGCTAAACGTAACGGTTTCGATGAAGGGATTGCACTCGA
TACTAACGGTTTAGTCAGCGAAGCCGCTGGTGCCAATATTTTTGTCATTAAAAAGAACAAGATCTACACACCTCCAGCCA
CAGCCGCTATTCTGATGGGGCTGACTCGAGACAGCATTATTACTCTTGCACGAGATAAAGGTTATCAAGTGGTTGAAGAG
CCGATGTCACGCGAGTTTCTCTACCTTGCCGATGAGATCTTTATGACCGGCACCGCGGCCGAAATTGTGCCGGTACGTAG
CGTCGATCGCATCGAGATAGGCAGCGGCAAGCGCGGTGAGATCACCAAAGAAATTCAGCAGAGCTTTTTCGGCCTGTTCA
GCGGTGAAACCGAAGACAAGTGGGGTTGGTTGGAGGCTTTGGAAGGCTAA

Upstream 100 bases:

>100_bases
TTGCTAACCAATCAAATAAATAAGCTTATTGATGTGATTGATTGCCAAGTATTGGTAAATAACACCGCAGTAGCATTAGC
ACAAAATAAAGGGTGAGAAT

Downstream 100 bases:

>100_bases
GACGAACGCTGTGCTGACGGAAAGGCCGGAAAAGCAGATCCTAGGTACTAGAAAAAGCTAAGAAAGGCCCTAGGAAAGCA
GAGGCTAAGACGAACGCTGT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAAKTAELIWFNGEMMPWGDAKVHVMSHALHYGTSVFEGIRVYDTHRGPAGFRLTEHIQRLFDSAKIYRMPIPYSFDNVM
QACRDATLGNGLKSAYIRPLAFYGDVGMGITPPKDAQCDLLVAAFPWGAYLGEDSMDAGVDVAVTSWNRLAPNTIPTGAK
AGGNYLSSLQISTEAKRNGFDEGIALDTNGLVSEAAGANIFVIKKNKIYTPPATAAILMGLTRDSIITLARDKGYQVVEE
PMSREFLYLADEIFMTGTAAEIVPVRSVDRIEIGSGKRGEITKEIQQSFFGLFSGETEDKWGWLEALEG

Sequences:

>Translated_309_residues
MAAKTAELIWFNGEMMPWGDAKVHVMSHALHYGTSVFEGIRVYDTHRGPAGFRLTEHIQRLFDSAKIYRMPIPYSFDNVM
QACRDATLGNGLKSAYIRPLAFYGDVGMGITPPKDAQCDLLVAAFPWGAYLGEDSMDAGVDVAVTSWNRLAPNTIPTGAK
AGGNYLSSLQISTEAKRNGFDEGIALDTNGLVSEAAGANIFVIKKNKIYTPPATAAILMGLTRDSIITLARDKGYQVVEE
PMSREFLYLADEIFMTGTAAEIVPVRSVDRIEIGSGKRGEITKEIQQSFFGLFSGETEDKWGWLEALEG
>Mature_308_residues
AAKTAELIWFNGEMMPWGDAKVHVMSHALHYGTSVFEGIRVYDTHRGPAGFRLTEHIQRLFDSAKIYRMPIPYSFDNVMQ
ACRDATLGNGLKSAYIRPLAFYGDVGMGITPPKDAQCDLLVAAFPWGAYLGEDSMDAGVDVAVTSWNRLAPNTIPTGAKA
GGNYLSSLQISTEAKRNGFDEGIALDTNGLVSEAAGANIFVIKKNKIYTPPATAAILMGLTRDSIITLARDKGYQVVEEP
MSREFLYLADEIFMTGTAAEIVPVRSVDRIEIGSGKRGEITKEIQQSFFGLFSGETEDKWGWLEALEG

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=319, Percent_Identity=25.3918495297806, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI296010904, Length=334, Percent_Identity=25.748502994012, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI296010906, Length=334, Percent_Identity=25.748502994012, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI38176287, Length=334, Percent_Identity=25.748502994012, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI48994963, Length=307, Percent_Identity=63.843648208469, Blast_Score=429, Evalue=1e-122,
Organism=Escherichia coli, GI1787338, Length=252, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17565728, Length=289, Percent_Identity=25.9515570934256, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322002, Length=317, Percent_Identity=26.1829652996845, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322608, Length=339, Percent_Identity=26.5486725663717, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641779, Length=282, Percent_Identity=27.3049645390071, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33808; Mature: 33677

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKTAELIWFNGEMMPWGDAKVHVMSHALHYGTSVFEGIRVYDTHRGPAGFRLTEHIQR
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHH
LFDSAKIYRMPIPYSFDNVMQACRDATLGNGLKSAYIRPLAFYGDVGMGITPPKDAQCDL
HHCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCEEEEECCCCCCCCCCCCCCCCE
LVAAFPWGAYLGEDSMDAGVDVAVTSWNRLAPNTIPTGAKAGGNYLSSLQISTEAKRNGF
EEEECCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHEEEEECHHHHCCC
DEGIALDTNGLVSEAAGANIFVIKKNKIYTPPATAAILMGLTRDSIITLARDKGYQVVEE
CCCEEECCCCCHHHCCCCEEEEEECCEEECCCHHHHHHHHCCCCCEEEEECCCCCHHHHH
PMSREFLYLADEIFMTGTAAEIVPVRSVDRIEIGSGKRGEITKEIQQSFFGLFSGETEDK
HHCCHHHEEEHHHHCCCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC
WGWLEALEG
CHHHHHCCC
>Mature Secondary Structure 
AAKTAELIWFNGEMMPWGDAKVHVMSHALHYGTSVFEGIRVYDTHRGPAGFRLTEHIQR
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHH
LFDSAKIYRMPIPYSFDNVMQACRDATLGNGLKSAYIRPLAFYGDVGMGITPPKDAQCDL
HHCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCEEEEECCCCCCCCCCCCCCCCE
LVAAFPWGAYLGEDSMDAGVDVAVTSWNRLAPNTIPTGAKAGGNYLSSLQISTEAKRNGF
EEEECCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHEEEEECHHHHCCC
DEGIALDTNGLVSEAAGANIFVIKKNKIYTPPATAAILMGLTRDSIITLARDKGYQVVEE
CCCEEECCCCCHHHCCCCEEEEEECCEEECCCHHHHHHHHCCCCCEEEEECCCCCHHHHH
PMSREFLYLADEIFMTGTAAEIVPVRSVDRIEIGSGKRGEITKEIQQSFFGLFSGETEDK
HHCCHHHEEEHHHHCCCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC
WGWLEALEG
CHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]