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The map label for this gene is yciR [C]

Identifier: 167625641

GI number: 167625641

Start: 4531786

End: 4534140

Strand: Reverse

Name: yciR [C]

Synonym: Shal_3736

Alternate gene names: 167625641

Gene position: 4534140-4531786 (Counterclockwise)

Preceding gene: 167625642

Following gene: 167625639

Centisome position: 86.75

GC content: 44.84

Gene sequence:

>2355_bases
ATGAAACACTTTAAGTGGTTTAACAGTAAAACAGCGATTATCGTTGCAGGCATTCTATTGAGTGCCTACTTGATCCTTAT
TCTGACGGTTACTAACTTAGGCCAGAGTCGTTTAAAGGAATCACAAAACAGCGCATTAAACCTTAGGGTCAGTAACTATA
CCGAAAACCTAAGTTTTTTCTTTGATGCCAGTGAAAAGAATATCGCCAATCTAAGTCAGAAGAGAGACGTCAATACTTAC
TTCTCTAACTTGGCCGCAGGGATGTCGTTGCAGTATGGCCTAGGCTCGAGCCTGTTTAGCCTGAGGCGAACGATAGATAA
TTTTAGCCAATCTAACAAAATGGATGGTCAGCTTATCTACTCTAGGGTGATGATTGTTGGCTTAGGGGAAACCGTTATTG
TCGATACTCATCCGGAGGTCGATTTTGAGGTTAACCAACTGCCTTTTAAAGAGATGGAGACGGTTAGCCATAAAGTTCAC
CTAGTCACAGATGAAAGTGGGCCGGTTATTCAGCTGCTGCAGACGATTTATCATCAGAATAAGCCAGTGGCGATCTTAGT
TGCCAGCCTCAATACCGATCTGGTGATCCGTATGCTGTCGACGCAAGAGCATTTAGATAGTGGCAGCTGTCTAACCTTAG
TCACTCCTGTTGGGGATATTGTCGTTTGGAATTCATTAAGTGGCTGTATATCCGATATTGAGCGCGGTACGACTAGCTAT
TATAGCGACTCATCAAGGATCATCTATTTTGAGAAAAATGTGGTCGCGACGCCGTTTAAACTAGAGAGTTGGTTTGAGCC
GGTGACTGAGCAAGATATTTTCACCTCTGCTTGGTTTATTGCGGCTATCTCATTGTTGGCACTGCCAGTATTTATGGGTT
TGATCTACCTTATGCGTGTGAACAATGCCAACTTAGTGCTGCAGACCCAAGTGGAGTTGTCTTCAGAACAGCAGCAAGAG
TTGGCGACACAAAACGCTCTATTGCATGAAGAGATCTGTAAACGTAAGGCATCAGAGAGCAAGCTTGCGTATCAGGCGAC
CCATGATGAACTGACTAATTTGGCAAACCGCACCCACGGCATGGCTAGGCTGCAAGAGGCCATTCGAGCAGCCCATGAAA
AGCAAACTCAAATTTTGTTGCTGTTTATCGATCTGGATAACTTTAAACAGGTTAACGATACCGTCGGCCATCATGCCGGA
GACCTGCTTTTAAAACAAACCAGTGAGCGCTTGCTAACATCGGTACGCCGTTCCGATATTGTTGCTCGTCTAGGTGGCGA
TGAGTTTTTGGTGATAGTGCCCGATATTCAGCATCAAGATTCAGCCAAACTGGTTGCTAGCAGTATTTTGTCTGTGTTTG
AGAAGCCATTTCATATTGAACAACAAGAATTTTTTGTCTCGACTAGCATTGGCATGTCTATCTATCCTAAAGATGGTAGG
AATGCTGCGACGCTGTTAAAGCGCGCCGATACCGCATTGTACAAGGTCAAAGATTTAGGCCGTAATGGCTTTAGTTTTTA
CGATGAAAGTATGAACTTAGATGTGCAGCGTAATTTTGCGCTCAATGTGCGATTACATCAGGCTGTTCAGCAAGGCGATA
TAGAGATCTACTATCAGCCGATATTGGACTTAACCAGCCGTAAAATTGTAGCCGCTGAAGCCCTGATGCGCTGGACCGAC
AGTGAATTAGGTTATGTGTCACCGGAGGACTTTATTCCGCTAGCGGAAAAGAATGGCTTAATCCATCGACTCGGCGATAT
CGTTTTACTCGAGGCTTGTACTCAGGCTGCTAGCTGGCAGACTATCAGTCCCATTAAGATCGCCATTAACTTCTCTAGTG
TTCAGTTTAGGTATTGCGAGCAACTGCAGTCGCGTATCGTCGATGTATTGATGCAGACGGGTTTGCCTGCATACCAGCTC
GATATGGAAGTGACCGAGAGTTTATTGATAGATCAAGGTCATGCCTTGATGAAGATGTTGTCATACCTTAAGCAGCTCGG
CGTAGGTTTATCTATCGATGATTTTGGTACCGGTTACTCGGCGCTAAGTTACTTACAGAGGTTTTCATTCACTAAGTTAA
AAATTGATCGTGCTTTTATCAATAATATGACCACCTGTTCATCGGATGCCTCTTTGGTGTCGGCGATATTGGCGATGGCT
AAATCGTTAAAGCTTAAAGTGGTTGCCGAGGGGATTGAAAATGAGCAACAAGCGCTGTTCTTGCAGGAGCACCGTTGTGA
GTATGGTCAGGGGTATTTGTTTAGTCGTCCGGTACCCGCAGCCGAGTTTACTCAGTTGCTACTTCGCGACCAGAAGGATG
CCAGTTTAGGGCAACAGGTTGAGCGAGTAAGCTAA

Upstream 100 bases:

>100_bases
GATGGCAGCTATAACAAGCTAGTGAAGAAGTATTACCCGACAGTTTTTCATTACTATCAAGACTATTTTGATAAATCAGC
GGCAGGTGTTCACAAGTAAC

Downstream 100 bases:

>100_bases
GTCTTCTACTCGCGCTATTTGCTTGATCTCAATATAAAAAATGGCCAGCTTATTATTTAATAACAAGCTGGCCATTTTTA
TTGGCTCTTATCTTATAGTA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 784; Mature: 784

Protein sequence:

>784_residues
MKHFKWFNSKTAIIVAGILLSAYLILILTVTNLGQSRLKESQNSALNLRVSNYTENLSFFFDASEKNIANLSQKRDVNTY
FSNLAAGMSLQYGLGSSLFSLRRTIDNFSQSNKMDGQLIYSRVMIVGLGETVIVDTHPEVDFEVNQLPFKEMETVSHKVH
LVTDESGPVIQLLQTIYHQNKPVAILVASLNTDLVIRMLSTQEHLDSGSCLTLVTPVGDIVVWNSLSGCISDIERGTTSY
YSDSSRIIYFEKNVVATPFKLESWFEPVTEQDIFTSAWFIAAISLLALPVFMGLIYLMRVNNANLVLQTQVELSSEQQQE
LATQNALLHEEICKRKASESKLAYQATHDELTNLANRTHGMARLQEAIRAAHEKQTQILLLFIDLDNFKQVNDTVGHHAG
DLLLKQTSERLLTSVRRSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFHIEQQEFFVSTSIGMSIYPKDGR
NAATLLKRADTALYKVKDLGRNGFSFYDESMNLDVQRNFALNVRLHQAVQQGDIEIYYQPILDLTSRKIVAAEALMRWTD
SELGYVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAASWQTISPIKIAINFSSVQFRYCEQLQSRIVDVLMQTGLPAYQL
DMEVTESLLIDQGHALMKMLSYLKQLGVGLSIDDFGTGYSALSYLQRFSFTKLKIDRAFINNMTTCSSDASLVSAILAMA
KSLKLKVVAEGIENEQQALFLQEHRCEYGQGYLFSRPVPAAEFTQLLLRDQKDASLGQQVERVS

Sequences:

>Translated_784_residues
MKHFKWFNSKTAIIVAGILLSAYLILILTVTNLGQSRLKESQNSALNLRVSNYTENLSFFFDASEKNIANLSQKRDVNTY
FSNLAAGMSLQYGLGSSLFSLRRTIDNFSQSNKMDGQLIYSRVMIVGLGETVIVDTHPEVDFEVNQLPFKEMETVSHKVH
LVTDESGPVIQLLQTIYHQNKPVAILVASLNTDLVIRMLSTQEHLDSGSCLTLVTPVGDIVVWNSLSGCISDIERGTTSY
YSDSSRIIYFEKNVVATPFKLESWFEPVTEQDIFTSAWFIAAISLLALPVFMGLIYLMRVNNANLVLQTQVELSSEQQQE
LATQNALLHEEICKRKASESKLAYQATHDELTNLANRTHGMARLQEAIRAAHEKQTQILLLFIDLDNFKQVNDTVGHHAG
DLLLKQTSERLLTSVRRSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFHIEQQEFFVSTSIGMSIYPKDGR
NAATLLKRADTALYKVKDLGRNGFSFYDESMNLDVQRNFALNVRLHQAVQQGDIEIYYQPILDLTSRKIVAAEALMRWTD
SELGYVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAASWQTISPIKIAINFSSVQFRYCEQLQSRIVDVLMQTGLPAYQL
DMEVTESLLIDQGHALMKMLSYLKQLGVGLSIDDFGTGYSALSYLQRFSFTKLKIDRAFINNMTTCSSDASLVSAILAMA
KSLKLKVVAEGIENEQQALFLQEHRCEYGQGYLFSRPVPAAEFTQLLLRDQKDASLGQQVERVS
>Mature_784_residues
MKHFKWFNSKTAIIVAGILLSAYLILILTVTNLGQSRLKESQNSALNLRVSNYTENLSFFFDASEKNIANLSQKRDVNTY
FSNLAAGMSLQYGLGSSLFSLRRTIDNFSQSNKMDGQLIYSRVMIVGLGETVIVDTHPEVDFEVNQLPFKEMETVSHKVH
LVTDESGPVIQLLQTIYHQNKPVAILVASLNTDLVIRMLSTQEHLDSGSCLTLVTPVGDIVVWNSLSGCISDIERGTTSY
YSDSSRIIYFEKNVVATPFKLESWFEPVTEQDIFTSAWFIAAISLLALPVFMGLIYLMRVNNANLVLQTQVELSSEQQQE
LATQNALLHEEICKRKASESKLAYQATHDELTNLANRTHGMARLQEAIRAAHEKQTQILLLFIDLDNFKQVNDTVGHHAG
DLLLKQTSERLLTSVRRSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFHIEQQEFFVSTSIGMSIYPKDGR
NAATLLKRADTALYKVKDLGRNGFSFYDESMNLDVQRNFALNVRLHQAVQQGDIEIYYQPILDLTSRKIVAAEALMRWTD
SELGYVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAASWQTISPIKIAINFSSVQFRYCEQLQSRIVDVLMQTGLPAYQL
DMEVTESLLIDQGHALMKMLSYLKQLGVGLSIDDFGTGYSALSYLQRFSFTKLKIDRAFINNMTTCSSDASLVSAILAMA
KSLKLKVVAEGIENEQQALFLQEHRCEYGQGYLFSRPVPAAEFTQLLLRDQKDASLGQQVERVS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=446, Percent_Identity=34.5291479820628, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI87081921, Length=419, Percent_Identity=32.6968973747017, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI226510982, Length=448, Percent_Identity=27.4553571428571, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=36.0995850622407, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=33.469387755102, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788502, Length=244, Percent_Identity=34.4262295081967, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1787055, Length=288, Percent_Identity=29.5138888888889, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=31.3253012048193, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081845, Length=254, Percent_Identity=31.8897637795276, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=35.6756756756757, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786507, Length=244, Percent_Identity=28.2786885245902, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1788849, Length=249, Percent_Identity=31.3253012048193, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=28.3950617283951, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=34.3558282208589, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081977, Length=163, Percent_Identity=33.1288343558282, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=33.1325301204819, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=34.3023255813954, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=171, Percent_Identity=32.7485380116959, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=30.1136363636364, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=31.9018404907975, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=32.9479768786127, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787410, Length=219, Percent_Identity=26.027397260274, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=96, Percent_Identity=36.4583333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=28.8343558282209, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=28.4023668639053, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 87979; Mature: 87979

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFKWFNSKTAIIVAGILLSAYLILILTVTNLGQSRLKESQNSALNLRVSNYTENLSFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCCCCEEEE
FDASEKNIANLSQKRDVNTYFSNLAAGMSLQYGLGSSLFSLRRTIDNFSQSNKMDGQLIY
EECCCCHHHHHHHHCCHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHH
SRVMIVGLGETVIVDTHPEVDFEVNQLPFKEMETVSHKVHLVTDESGPVIQLLQTIYHQN
HHHHEEECCCEEEEECCCCCCEEECCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCC
KPVAILVASLNTDLVIRMLSTQEHLDSGSCLTLVTPVGDIVVWNSLSGCISDIERGTTSY
CCEEEEEEECCCCHHHEEHHHHHHCCCCCEEEEEECCCCEEEECCHHHHHHHHHHCCCCC
YSDSSRIIYFEKNVVATPFKLESWFEPVTEQDIFTSAWFIAAISLLALPVFMGLIYLMRV
CCCCCEEEEEECCEEECCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
NNANLVLQTQVELSSEQQQELATQNALLHEEICKRKASESKLAYQATHDELTNLANRTHG
CCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHH
MARLQEAIRAAHEKQTQILLLFIDLDNFKQVNDTVGHHAGDLLLKQTSERLLTSVRRSDI
HHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFHIEQQEFFVSTSIGMSIYPKDGR
HEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCEEECCCCC
NAATLLKRADTALYKVKDLGRNGFSFYDESMNLDVQRNFALNVRLHQAVQQGDIEIYYQP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCEEEEHHHHHHHHHCCEEEEEEE
ILDLTSRKIVAAEALMRWTDSELGYVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAASWQ
HHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCC
TISPIKIAINFSSVQFRYCEQLQSRIVDVLMQTGLPAYQLDMEVTESLLIDQGHALMKML
CCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCHHHHHHH
SYLKQLGVGLSIDDFGTGYSALSYLQRFSFTKLKIDRAFINNMTTCSSDASLVSAILAMA
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHEEEHHHHHCCCCCCCCHHHHHHHHHHHH
KSLKLKVVAEGIENEQQALFLQEHRCEYGQGYLFSRPVPAAEFTQLLLRDQKDASLGQQV
HHCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHH
ERVS
HHCC
>Mature Secondary Structure
MKHFKWFNSKTAIIVAGILLSAYLILILTVTNLGQSRLKESQNSALNLRVSNYTENLSFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCCCCEEEE
FDASEKNIANLSQKRDVNTYFSNLAAGMSLQYGLGSSLFSLRRTIDNFSQSNKMDGQLIY
EECCCCHHHHHHHHCCHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHH
SRVMIVGLGETVIVDTHPEVDFEVNQLPFKEMETVSHKVHLVTDESGPVIQLLQTIYHQN
HHHHEEECCCEEEEECCCCCCEEECCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCC
KPVAILVASLNTDLVIRMLSTQEHLDSGSCLTLVTPVGDIVVWNSLSGCISDIERGTTSY
CCEEEEEEECCCCHHHEEHHHHHHCCCCCEEEEEECCCCEEEECCHHHHHHHHHHCCCCC
YSDSSRIIYFEKNVVATPFKLESWFEPVTEQDIFTSAWFIAAISLLALPVFMGLIYLMRV
CCCCCEEEEEECCEEECCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
NNANLVLQTQVELSSEQQQELATQNALLHEEICKRKASESKLAYQATHDELTNLANRTHG
CCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHH
MARLQEAIRAAHEKQTQILLLFIDLDNFKQVNDTVGHHAGDLLLKQTSERLLTSVRRSDI
HHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFHIEQQEFFVSTSIGMSIYPKDGR
HEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCEEECCCCC
NAATLLKRADTALYKVKDLGRNGFSFYDESMNLDVQRNFALNVRLHQAVQQGDIEIYYQP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCEEEEHHHHHHHHHCCEEEEEEE
ILDLTSRKIVAAEALMRWTDSELGYVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAASWQ
HHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCC
TISPIKIAINFSSVQFRYCEQLQSRIVDVLMQTGLPAYQLDMEVTESLLIDQGHALMKML
CCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCHHHHHHH
SYLKQLGVGLSIDDFGTGYSALSYLQRFSFTKLKIDRAFINNMTTCSSDASLVSAILAMA
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHEEEHHHHHCCCCCCCCHHHHHHHHHHHH
KSLKLKVVAEGIENEQQALFLQEHRCEYGQGYLFSRPVPAAEFTQLLLRDQKDASLGQQV
HHCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHH
ERVS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]