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The map label for this gene is hflK [H]

Identifier: 167625538

GI number: 167625538

Start: 4428602

End: 4429747

Strand: Reverse

Name: hflK [H]

Synonym: Shal_3632

Alternate gene names: 167625538

Gene position: 4429747-4428602 (Counterclockwise)

Preceding gene: 167625539

Following gene: 167625537

Centisome position: 84.75

GC content: 45.2

Gene sequence:

>1146_bases
ATGGCTTGGAACGAGCCCGGTAACAAGGGTCAAGACCCTTGGGGAAATAAGGGTGGTAATGATAAAGGACCACCAGATCT
AGATGAAGTTTTTCGTAATCTTTCGAAGCGCTTCGGCGGCAAAGGCAATGGTTCTGGTGGCAGCGTTAGCGGTGTCAGCT
TAGTCATAGTCCTTGTTATTGCCGTTGTTGTATGGGGCCTATCGGGTTTCTATACAATAAAAGAAGCTGAGAAAGGGGTA
GAGCTCCGTTTTGGTGCGTATATTGGTGAAGTTGATCCAGGCCTTCAATGGAAAGCCACTTTTATTGATGAAGTGACACC
AGTAAACGTACAAACCGTTCGCTCAATTCCAGCTTCAGGAAGCATGCTGACAGCCGACGAGAACGTTGTTCTTGTACAGC
TTGATGTTCAGTACCGAGTGAATAACGCTGAAAATTATTTGTATAGCGTAGTTGATGCAGACGCGAGTTTGCGTGAAGCG
ACAGACAGTGCGCTTCGCTATGTTATCGGCCATAACACTATGGATGATATCTTGACGACTGGTCGAGATAAAATTCGTCG
TGATACATGGGATGAGATTGAGCGAATTATCAAGCCTTACAAACTAGGTATTATGGTTGTTGATGTGAACTTCTTGCCTG
CACGTCCGCCAGAAGAGGTGAAAGACGCCTTTGATGACGCTATTGCAGCACAAGAGGATGAGCAGCGCTTTATTCGTGAA
GCTGAAGCATACTCACGCCAGTTAGAGCCAAAGGTTCGTGGTACTGTGCAGCGTATGGATCAACAAGCAATTGCGTATAA
GCAAAAAGTAACCCTAGAAGCACAAGGTAAGGTAGCTCGTTTCAATCAGTTACTACCTGAGTATCAAGCCGCACCAGAAG
TGACTCGTGAGCGTATGTATTTTGATACGATGCAAGAGATTATGAGCGGTACAAGTAAAGTACTTATTGATGCTAAGAAT
AGCGGTAACTTGATGTATCTACCGTTAGACAAGCTGATGCAGAATAGCCAAGCGCATAAGTCTGCAAGTGCTAAGAGTAA
ACCGGCAACGTCTGTTATGTCAGTTAATAGTACAACTCATACTAACAGCAGTATTCCTCTTGATGGTCGCCCATCTCGAG
GTGAACGTTCGTTGGGGAGGAACTAA

Upstream 100 bases:

>100_bases
CAGAGCCAAGGTGAAATAGAGACTTTTGTCGTCGACCCTGTCGTCGCATAATTAAGTATTTTAGTAATCTCGTTTATTTC
ATACACTTATGGAGTACTAA

Downstream 100 bases:

>100_bases
TTGATGGGTAGATTTACAGCGATAATCGTAGCGGTACTTATTGCGATCTCTTTATCTTCACTATTAGTTGTGAATGAAGG
CGAGCGTGCCATCGTTTCTC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MAWNEPGNKGQDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSVSGVSLVIVLVIAVVVWGLSGFYTIKEAEKGV
ELRFGAYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASGSMLTADENVVLVQLDVQYRVNNAENYLYSVVDADASLREA
TDSALRYVIGHNTMDDILTTGRDKIRRDTWDEIERIIKPYKLGIMVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIRE
AEAYSRQLEPKVRGTVQRMDQQAIAYKQKVTLEAQGKVARFNQLLPEYQAAPEVTRERMYFDTMQEIMSGTSKVLIDAKN
SGNLMYLPLDKLMQNSQAHKSASAKSKPATSVMSVNSTTHTNSSIPLDGRPSRGERSLGRN

Sequences:

>Translated_381_residues
MAWNEPGNKGQDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSVSGVSLVIVLVIAVVVWGLSGFYTIKEAEKGV
ELRFGAYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASGSMLTADENVVLVQLDVQYRVNNAENYLYSVVDADASLREA
TDSALRYVIGHNTMDDILTTGRDKIRRDTWDEIERIIKPYKLGIMVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIRE
AEAYSRQLEPKVRGTVQRMDQQAIAYKQKVTLEAQGKVARFNQLLPEYQAAPEVTRERMYFDTMQEIMSGTSKVLIDAKN
SGNLMYLPLDKLMQNSQAHKSASAKSKPATSVMSVNSTTHTNSSIPLDGRPSRGERSLGRN
>Mature_380_residues
AWNEPGNKGQDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSVSGVSLVIVLVIAVVVWGLSGFYTIKEAEKGVE
LRFGAYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASGSMLTADENVVLVQLDVQYRVNNAENYLYSVVDADASLREAT
DSALRYVIGHNTMDDILTTGRDKIRRDTWDEIERIIKPYKLGIMVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIREA
EAYSRQLEPKVRGTVQRMDQQAIAYKQKVTLEAQGKVARFNQLLPEYQAAPEVTRERMYFDTMQEIMSGTSKVLIDAKNS
GNLMYLPLDKLMQNSQAHKSASAKSKPATSVMSVNSTTHTNSSIPLDGRPSRGERSLGRN

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=375, Percent_Identity=55.4666666666667, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 42150; Mature: 42019

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNEPGNKGQDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSVSGVSLVIVLVI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AVVVWGLSGFYTIKEAEKGVELRFGAYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASG
HHHHHCCCCEEEEHHHCCCCEEEEEEEECCCCCCCEEEEEHHCCCCCCCHHHHHCCCCCC
SMLTADENVVLVQLDVQYRVNNAENYLYSVVDADASLREATDSALRYVIGHNTMDDILTT
CEEECCCCEEEEEEEEEEEECCHHHHEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHC
GRDKIRRDTWDEIERIIKPYKLGIMVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIRE
CHHHHHCCCHHHHHHHHCHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
AEAYSRQLEPKVRGTVQRMDQQAIAYKQKVTLEAQGKVARFNQLLPEYQAAPEVTRERMY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCHHHHHHHHH
FDTMQEIMSGTSKVLIDAKNSGNLMYLPLDKLMQNSQAHKSASAKSKPATSVMSVNSTTH
HHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHCCHHHHHHCCCCCCCCCCEEEECCCCC
TNSSIPLDGRPSRGERSLGRN
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWNEPGNKGQDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSVSGVSLVIVLVI
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AVVVWGLSGFYTIKEAEKGVELRFGAYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASG
HHHHHCCCCEEEEHHHCCCCEEEEEEEECCCCCCCEEEEEHHCCCCCCCHHHHHCCCCCC
SMLTADENVVLVQLDVQYRVNNAENYLYSVVDADASLREATDSALRYVIGHNTMDDILTT
CEEECCCCEEEEEEEEEEEECCHHHHEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHC
GRDKIRRDTWDEIERIIKPYKLGIMVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIRE
CHHHHHCCCHHHHHHHHCHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
AEAYSRQLEPKVRGTVQRMDQQAIAYKQKVTLEAQGKVARFNQLLPEYQAAPEVTRERMY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCHHHHHHHHH
FDTMQEIMSGTSKVLIDAKNSGNLMYLPLDKLMQNSQAHKSASAKSKPATSVMSVNSTTH
HHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHCCHHHHHHCCCCCCCCCCEEEECCCCC
TNSSIPLDGRPSRGERSLGRN
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]