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The map label for this gene is hflC [H]

Identifier: 167625537

GI number: 167625537

Start: 4427720

End: 4428598

Strand: Reverse

Name: hflC [H]

Synonym: Shal_3631

Alternate gene names: 167625537

Gene position: 4428598-4427720 (Counterclockwise)

Preceding gene: 167625538

Following gene: 167625536

Centisome position: 84.73

GC content: 43.0

Gene sequence:

>879_bases
ATGGGTAGATTTACAGCGATAATCGTAGCGGTACTTATTGCGATCTCTTTATCTTCACTATTAGTTGTGAATGAAGGCGA
GCGTGCCATCGTTTCTCGATTTGGTAAGGTACTAAAAGACGACGGTGTGACGCGTGTTTATGCTCCAGGACTTCATTTGA
AGATCCCGATGCTTGATAAAATTAAGTATATGGATTCACGAGTGCAAACTTTGGATGGCGCAGCAGATCGCTTTGTAACG
TCAGAGAAAAAAGACTTGATGGTCGATTCATACGTGAAGTGGCGCATTAAAGACTTTGAACGTTATTACCTTTCGACTAA
CGGTGGTATTAAGGCTAACGCTGAAACCTTGTTACAGCGTAAGATCAATAACGATCTTCGTACCGAGTTTGGTCGCAGAA
CCATTAAAGAGATTGTTTCTGGTAGCCGTGATGAGCTGCAATCAGATGCGCTTAAAAATGCTGCTGAGAGTGCTAAAGAC
TTAGGTGTTGAGGTAGTTGATGTGCGAGTTAAGCAGATTAACTTACCAGCAAACGTCAGTACCAGTATTTACCAGCGTAT
GCGTGCAGAACGTCAAGCTGTGGCTAAAGAGCATCGCGCTCAAGGTCAAGAGCAAGCGGAAATTATCCGTGCGAAGACTG
ACGCAAGTGTGACTATTCAGACTGCAGAAGCAGAGCGTAAAGCTTTGACTATTCGCGGTGAAGGTGACGCAGAAGCAGCT
AAGATTTATGCCGATGCATATACTAAAGATCCTGAGTTCTTTAGCTTTATGCGAAGCTTAGATGCTTATAAAGCAAGTTT
CTCTGGTAAGAATGACGTTATGGTGCTTGAGCCTGATAGTGAGTTCTTCAGATATATGAATAGTTCATCTGGAAAGTAG

Upstream 100 bases:

>100_bases
GTCTGTTATGTCAGTTAATAGTACAACTCATACTAACAGCAGTATTCCTCTTGATGGTCGCCCATCTCGAGGTGAACGTT
CGTTGGGGAGGAACTAATTG

Downstream 100 bases:

>100_bases
TTATTCTAAAGTTTTATAAAAAAGGTCTAACGCAAGTTAGGCCTTTTTTTATGCCTGTCTGATTTATGTTAGCCACTATT
GTTTATTCCTAGCTCTTCAG

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MGRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDKIKYMDSRVQTLDGAADRFVT
SEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQRKINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKD
LGVEVVDVRVKQINLPANVSTSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
KIYADAYTKDPEFFSFMRSLDAYKASFSGKNDVMVLEPDSEFFRYMNSSSGK

Sequences:

>Translated_292_residues
MGRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDKIKYMDSRVQTLDGAADRFVT
SEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQRKINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKD
LGVEVVDVRVKQINLPANVSTSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
KIYADAYTKDPEFFSFMRSLDAYKASFSGKNDVMVLEPDSEFFRYMNSSSGK
>Mature_291_residues
GRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDKIKYMDSRVQTLDGAADRFVTS
EKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQRKINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKDL
GVEVVDVRVKQINLPANVSTSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAAK
IYADAYTKDPEFFSFMRSLDAYKASFSGKNDVMVLEPDSEFFRYMNSSSGK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=312, Percent_Identity=52.5641025641026, Blast_Score=323, Evalue=8e-90,
Organism=Escherichia coli, GI1786697, Length=289, Percent_Identity=24.5674740484429, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 32697; Mature: 32565

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDK
CCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCEEECCHHHH
IKYMDSRVQTLDGAADRFVTSEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQR
HHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHH
KINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKDLGVEVVDVRVKQINLPANVS
HHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCC
TSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
KIYADAYTKDPEFFSFMRSLDAYKASFSGKNDVMVLEPDSEFFRYMNSSSGK
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCC
>Mature Secondary Structure 
GRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDK
CHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCEEECCHHHH
IKYMDSRVQTLDGAADRFVTSEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQR
HHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHH
KINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKDLGVEVVDVRVKQINLPANVS
HHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCC
TSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
KIYADAYTKDPEFFSFMRSLDAYKASFSGKNDVMVLEPDSEFFRYMNSSSGK
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]