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The map label for this gene is gfa [H]

Identifier: 167625384

GI number: 167625384

Start: 4229499

End: 4230098

Strand: Reverse

Name: gfa [H]

Synonym: Shal_3474

Alternate gene names: 167625384

Gene position: 4230098-4229499 (Counterclockwise)

Preceding gene: 167625390

Following gene: 167625383

Centisome position: 80.93

GC content: 40.5

Gene sequence:

>600_bases
ATGATTTCTAAAATATTAAAACTTTTTCTGAGAAAAAATAGTACCAAGGTATTAATTCACCCATCTGTTGATAATAATAT
TTTCCCTATATTGTCCGGTTTTAGTGGTGGTTCGTTAACGTGTCACTGTAAGAGCAAGCCTGTTACTGTAAGGCTAAGCG
GTCAAACAGCACATAACCATGTATGCGGCTGCTCAAAGTGCTGGAAGCCTAAAGGTGCTTCATTCTCTCAAGTTGCAGTG
ATTGGACGTGATAACGTTAAGATAACTGCAAACGAAAGCAAATTAGTCGTGGTTGATGCTGAAGCAGCCATTAATCGTTA
TGCCTGTAAAGATTGTGGCGTACATATGTATGGCCGTATTCATAATGAGGCCCATCCATTTTTTGGTTTAGACTTTGTCC
ATACAGAGCTAAGCAAGCAATCAGGCTGGGCACCAGCAGAATTTGCTGCATTTGTGTCATCAATTATTGAAACAGGCACC
AACCCTGAAAATATGCCTGCGATCCGTGAGCGTTTATTGGAGCTAGGGTTAGAGCCATATGATTGCTTATCACCAGATCT
AATGGATGCGATTGCAGCACATGTTGCTAAAAAAGCTTAA

Upstream 100 bases:

>100_bases
AGTAGCTAACTCATTAAGTAATAATTGGAGTCTCTCAATTAAAATTTTGAGACTAATAGCTCAACGATTTCAGTTGTTAA
TTATTCTGTTTGTATTGATT

Downstream 100 bases:

>100_bases
TTAGCAATCAATAGTTATTCGTAGACTCTAGATTAAAAAAGCCCCAATCATAATAATTCTCATGATTGGGGCTTTTTGTT
GGACAGATGATTGTTCGCCC

Product: glutathione-dependent formaldehyde-activating protein

Products: NA

Alternate protein names: S-(hydroxymethyl)glutathione synthase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MISKILKLFLRKNSTKVLIHPSVDNNIFPILSGFSGGSLTCHCKSKPVTVRLSGQTAHNHVCGCSKCWKPKGASFSQVAV
IGRDNVKITANESKLVVVDAEAAINRYACKDCGVHMYGRIHNEAHPFFGLDFVHTELSKQSGWAPAEFAAFVSSIIETGT
NPENMPAIRERLLELGLEPYDCLSPDLMDAIAAHVAKKA

Sequences:

>Translated_199_residues
MISKILKLFLRKNSTKVLIHPSVDNNIFPILSGFSGGSLTCHCKSKPVTVRLSGQTAHNHVCGCSKCWKPKGASFSQVAV
IGRDNVKITANESKLVVVDAEAAINRYACKDCGVHMYGRIHNEAHPFFGLDFVHTELSKQSGWAPAEFAAFVSSIIETGT
NPENMPAIRERLLELGLEPYDCLSPDLMDAIAAHVAKKA
>Mature_199_residues
MISKILKLFLRKNSTKVLIHPSVDNNIFPILSGFSGGSLTCHCKSKPVTVRLSGQTAHNHVCGCSKCWKPKGASFSQVAV
IGRDNVKITANESKLVVVDAEAAINRYACKDCGVHMYGRIHNEAHPFFGLDFVHTELSKQSGWAPAEFAAFVSSIIETGT
NPENMPAIRERLLELGLEPYDCLSPDLMDAIAAHVAKKA

Specific function: Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione [H]

COG id: COG3791

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfa family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014185
- InterPro:   IPR006913
- InterPro:   IPR011057 [H]

Pfam domain/function: PF04828 GFA [H]

EC number: =4.4.1.22 [H]

Molecular weight: Translated: 21663; Mature: 21663

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKILKLFLRKNSTKVLIHPSVDNNIFPILSGFSGGSLTCHCKSKPVTVRLSGQTAHNH
CHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCC
VCGCSKCWKPKGASFSQVAVIGRDNVKITANESKLVVVDAEAAINRYACKDCGVHMYGRI
CCCCHHHCCCCCCCCCEEEEEECCCEEEEECCCEEEEEECHHHHHHHHHHHCCEEEEEEE
HNEAHPFFGLDFVHTELSKQSGWAPAEFAAFVSSIIETGTNPENMPAIRERLLELGLEPY
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCC
DCLSPDLMDAIAAHVAKKA
CCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISKILKLFLRKNSTKVLIHPSVDNNIFPILSGFSGGSLTCHCKSKPVTVRLSGQTAHNH
CHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCC
VCGCSKCWKPKGASFSQVAVIGRDNVKITANESKLVVVDAEAAINRYACKDCGVHMYGRI
CCCCHHHCCCCCCCCCEEEEEECCCEEEEECCCEEEEEECHHHHHHHHHHHCCEEEEEEE
HNEAHPFFGLDFVHTELSKQSGWAPAEFAAFVSSIIETGTNPENMPAIRERLLELGLEPY
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCC
DCLSPDLMDAIAAHVAKKA
CCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]