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The map label for this gene is mdtN [H]

Identifier: 167625255

GI number: 167625255

Start: 4084276

End: 4085394

Strand: Reverse

Name: mdtN [H]

Synonym: Shal_3344

Alternate gene names: 167625255

Gene position: 4085394-4084276 (Counterclockwise)

Preceding gene: 167625256

Following gene: 167625254

Centisome position: 78.16

GC content: 45.58

Gene sequence:

>1119_bases
ATGCCAACAAGTAAAGATACTGCATCAACTGGTGATTCCGAAATTACTCAGAAAAAAACGGTTGCCTCCTCTAAGCGTGT
GACGTGGATTTTATTAGTTATTGTCTTTTTATTATGGATTTATACGCTCTGGGCTGATCGTGTTACTCCGATGAATAATC
ACGCGAGAGTTAACGCTCAATTGATCCAAATCACTCCTCAAGTTTCCGCTGATATTTACAAGGTATCAGTGCTCAATAAT
GCAGAGGTCCGCCAAGGCGACGCTCTAGTTGATTTAGATAATGCCCCTTTTTTATTAAAAATCACCGCCGCTCGCCTACA
TTTGCAGCAAACAACGTTGTCATTAGGGGCTGATTCGGCAGGGATCCAAGAGGCTCAAGCCAACTTAGTGGCTAGCGAAA
TCAAACATGATAATGCCTTTAAACATACTCAGCGAATGGCGGCTTTAGGGCGCACAGGGGTGATAAGCAAGCAGTCTTTA
GAGGACAGTCAAGATCAGCTTAAAGATGCCGAGGCGCAGGTCGTTCAAGCTAAGGCCGCACTTGAACGCGCCAAAAAAGC
TCTTGGACCAAAGGGTGAAAATAATCCACAGCTGCAAAGTGCGCTTAATCAGCTCCATCAAGCACTACTTGAAGAGTCAT
ATTGTCACCTGCGATCACCAGGTGACGGAGTCATTACTCACCTTAATTTGGCGGCGGGTAATTTTGCTGTAGCAGGTCAC
CCTTTAATCACCTTTATCAATAATAAGCACACTTGGATCACCGCGATGCTGAGGGAGAACTCTCTCATTTATTTGAAACC
GGGTACGCCTGTTAAAATTGTATTTGATGCCTATCCCGGCCAAGTCTTTCGTGGTGAGGTGCAATCTATTGGCTGGGGAA
GCAGTGGTAATGGCAATTTACAAACCGATCAAACGACGGGATTATTGATCTCTCCTGATGGGCTGCAACACTCGCAACGT
TTTCCTGTCAATATCAATCTCGGGCCGGAGGCGAGTGCATTACAGCAGCGCTATGGTGCTCGAGCCATGATAAGTTTTTA
CCCTGGGGAGTCGGGGGTAGGTGAAACATTGTTGAATATATGGACTTGGACTTGGAGCTACTTATCCTATGTTTCATAG

Upstream 100 bases:

>100_bases
AACAGGTTCATTGTACCTATACCTACGACTTCCGTTTTAGAGGCTTAGTTGTGGGCATGTCGACTAACCCAATCACCTCA
TACTATGAAGATGAAAACTT

Downstream 100 bases:

>100_bases
CCGGGCAAATGCGCTGATCCGATTGGCTGTATTTCCAGTTTTATTGTTATATTGGCAGGATTTTTACGGTACACGTCTAC
CACTACTTGGGCCTGCCTTG

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MPTSKDTASTGDSEITQKKTVASSKRVTWILLVIVFLLWIYTLWADRVTPMNNHARVNAQLIQITPQVSADIYKVSVLNN
AEVRQGDALVDLDNAPFLLKITAARLHLQQTTLSLGADSAGIQEAQANLVASEIKHDNAFKHTQRMAALGRTGVISKQSL
EDSQDQLKDAEAQVVQAKAALERAKKALGPKGENNPQLQSALNQLHQALLEESYCHLRSPGDGVITHLNLAAGNFAVAGH
PLITFINNKHTWITAMLRENSLIYLKPGTPVKIVFDAYPGQVFRGEVQSIGWGSSGNGNLQTDQTTGLLISPDGLQHSQR
FPVNINLGPEASALQQRYGARAMISFYPGESGVGETLLNIWTWTWSYLSYVS

Sequences:

>Translated_372_residues
MPTSKDTASTGDSEITQKKTVASSKRVTWILLVIVFLLWIYTLWADRVTPMNNHARVNAQLIQITPQVSADIYKVSVLNN
AEVRQGDALVDLDNAPFLLKITAARLHLQQTTLSLGADSAGIQEAQANLVASEIKHDNAFKHTQRMAALGRTGVISKQSL
EDSQDQLKDAEAQVVQAKAALERAKKALGPKGENNPQLQSALNQLHQALLEESYCHLRSPGDGVITHLNLAAGNFAVAGH
PLITFINNKHTWITAMLRENSLIYLKPGTPVKIVFDAYPGQVFRGEVQSIGWGSSGNGNLQTDQTTGLLISPDGLQHSQR
FPVNINLGPEASALQQRYGARAMISFYPGESGVGETLLNIWTWTWSYLSYVS
>Mature_371_residues
PTSKDTASTGDSEITQKKTVASSKRVTWILLVIVFLLWIYTLWADRVTPMNNHARVNAQLIQITPQVSADIYKVSVLNNA
EVRQGDALVDLDNAPFLLKITAARLHLQQTTLSLGADSAGIQEAQANLVASEIKHDNAFKHTQRMAALGRTGVISKQSLE
DSQDQLKDAEAQVVQAKAALERAKKALGPKGENNPQLQSALNQLHQALLEESYCHLRSPGDGVITHLNLAAGNFAVAGHP
LITFINNKHTWITAMLRENSLIYLKPGTPVKIVFDAYPGQVFRGEVQSIGWGSSGNGNLQTDQTTGLLISPDGLQHSQRF
PVNINLGPEASALQQRYGARAMISFYPGESGVGETLLNIWTWTWSYLSYVS

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=324, Percent_Identity=27.4691358024691, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790024, Length=279, Percent_Identity=29.0322580645161, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788711, Length=325, Percent_Identity=25.8461538461538, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790012, Length=284, Percent_Identity=26.056338028169, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789041, Length=303, Percent_Identity=26.0726072607261, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081951, Length=311, Percent_Identity=23.1511254019293, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40660; Mature: 40528

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSKDTASTGDSEITQKKTVASSKRVTWILLVIVFLLWIYTLWADRVTPMNNHARVNAQ
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
LIQITPQVSADIYKVSVLNNAEVRQGDALVDLDNAPFLLKITAARLHLQQTTLSLGADSA
EEEECCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCC
GIQEAQANLVASEIKHDNAFKHTQRMAALGRTGVISKQSLEDSQDQLKDAEAQVVQAKAA
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
LERAKKALGPKGENNPQLQSALNQLHQALLEESYCHLRSPGDGVITHLNLAAGNFAVAGH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEECC
PLITFINNKHTWITAMLRENSLIYLKPGTPVKIVFDAYPGQVFRGEVQSIGWGSSGNGNL
CEEEEECCCCEEEEEEEECCCEEEECCCCCEEEEEECCCCCEECCHHHHCCCCCCCCCCE
QTDQTTGLLISPDGLQHSQRFPVNINLGPEASALQQRYGARAMISFYPGESGVGETLLNI
ECCCCCEEEECCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
WTWTWSYLSYVS
HHHHHHHHHHCC
>Mature Secondary Structure 
PTSKDTASTGDSEITQKKTVASSKRVTWILLVIVFLLWIYTLWADRVTPMNNHARVNAQ
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
LIQITPQVSADIYKVSVLNNAEVRQGDALVDLDNAPFLLKITAARLHLQQTTLSLGADSA
EEEECCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCC
GIQEAQANLVASEIKHDNAFKHTQRMAALGRTGVISKQSLEDSQDQLKDAEAQVVQAKAA
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
LERAKKALGPKGENNPQLQSALNQLHQALLEESYCHLRSPGDGVITHLNLAAGNFAVAGH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEECC
PLITFINNKHTWITAMLRENSLIYLKPGTPVKIVFDAYPGQVFRGEVQSIGWGSSGNGNL
CEEEEECCCCEEEEEEEECCCEEEECCCCCEEEEEECCCCCEECCHHHHCCCCCCCCCCE
QTDQTTGLLISPDGLQHSQRFPVNINLGPEASALQQRYGARAMISFYPGESGVGETLLNI
ECCCCCEEEECCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
WTWTWSYLSYVS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]