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The map label for this gene is tpiA [H]

Identifier: 167625063

GI number: 167625063

Start: 3846944

End: 3847726

Strand: Reverse

Name: tpiA [H]

Synonym: Shal_3151

Alternate gene names: 167625063

Gene position: 3847726-3846944 (Counterclockwise)

Preceding gene: 167625064

Following gene: 167625062

Centisome position: 73.61

GC content: 45.08

Gene sequence:

>783_bases
ATGGCACTCAGACGTCCCATGGTTGCTGGTAATTGGAAAATGAATGGCAGTGCGCAACTTGCGCAAGAGCTTTTCAAAAA
ATTCGCTACCAAGCTCCAAGATGATTCAGCGGAAGTGGTATTGTGTCCACCTTCTATTTACTTAGAGAGTGTACGACAGC
TACTGGATGAAAATAAAGAAGCCTTAAATGGTTGCTTAGTCAGAATGGGCGCGCAAAACCTAAGTCAACATGACTTTGGT
GCTTATACTGGTGAAATATCTGGTCAGATGTTAAAAGATTCCGGATGTCGATATGTTATTATCGGGCATTCAGAGCGTCG
CCGTATGTACGGAGAGACGAGTGTTATCGTGGCAGAGAAATTTGCTGCAGCTCAGAAACATGGTTTGACCCCAATATTAT
GTGTTGGTGAGTCGGGTCCAGCTCGTGAAGCAAGACGCACTTTTGAAGTGATTGCCGAAGAGTTAGATGTGGTCATTGAA
AAAAATGGTACCATGGCTTTTGACAACGCAATTATCGCCTACGAGCCATTATGGGCAGTAGGGACAGGTAAGAGCGCTAC
GCCAGAGCAGGCACAGGAAGTTCATGCGTTTATTCGCAAACGCCTCTCTGAAGTATCTCCATTTATCGGAGAAAATATCA
GGATTTTGTACGGTGGTAGCGTAACACCGAGTAATGCAGCAGACTTGTTTGCTCAACCTGATGTAGACGGTGGATTGATT
GGCGGTGTAAGCCTCAATGCTACCGAATTTCTCAGTTTATGTACGATAGCGATGAGCGCATAA

Upstream 100 bases:

>100_bases
AACACGCGTTCTCGCCGTATTTTTGAAAAATAACGCCTTTAGGTATTGTAACTTAACAAGCGGTTCGCTATTATTCTCGC
CGCTTTCAAAGGAGACAGTG

Downstream 100 bases:

>100_bases
TATGTATGAAGTTCTAATGATTATTTACTTGATGGTTGCGATTGGTCTAGTTGGCCTTATCCTTATCCAGCAAGGTAAAG
GTGCTGACATGGGGGCCTCA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MALRRPMVAGNWKMNGSAQLAQELFKKFATKLQDDSAEVVLCPPSIYLESVRQLLDENKEALNGCLVRMGAQNLSQHDFG
AYTGEISGQMLKDSGCRYVIIGHSERRRMYGETSVIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIE
KNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
GGVSLNATEFLSLCTIAMSA

Sequences:

>Translated_260_residues
MALRRPMVAGNWKMNGSAQLAQELFKKFATKLQDDSAEVVLCPPSIYLESVRQLLDENKEALNGCLVRMGAQNLSQHDFG
AYTGEISGQMLKDSGCRYVIIGHSERRRMYGETSVIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIE
KNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
GGVSLNATEFLSLCTIAMSA
>Mature_259_residues
ALRRPMVAGNWKMNGSAQLAQELFKKFATKLQDDSAEVVLCPPSIYLESVRQLLDENKEALNGCLVRMGAQNLSQHDFGA
YTGEISGQMLKDSGCRYVIIGHSERRRMYGETSVIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIEK
NGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLIG
GVSLNATEFLSLCTIAMSA

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=252, Percent_Identity=43.6507936507937, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI226529917, Length=252, Percent_Identity=43.6507936507937, Blast_Score=194, Evalue=5e-50,
Organism=Escherichia coli, GI1790353, Length=259, Percent_Identity=47.1042471042471, Blast_Score=248, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17536593, Length=244, Percent_Identity=43.8524590163934, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320255, Length=251, Percent_Identity=40.6374501992032, Blast_Score=184, Evalue=1e-47,
Organism=Drosophila melanogaster, GI28572008, Length=251, Percent_Identity=44.6215139442231, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI28572006, Length=251, Percent_Identity=44.6215139442231, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI28572004, Length=251, Percent_Identity=44.6215139442231, Blast_Score=208, Evalue=3e-54,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 28187; Mature: 28055

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRRPMVAGNWKMNGSAQLAQELFKKFATKLQDDSAEVVLCPPSIYLESVRQLLDENKE
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCHH
ALNGCLVRMGAQNLSQHDFGAYTGEISGQMLKDSGCRYVIIGHSERRRMYGETSVIVAEK
HHHHHHHHHCHHHCCCCCCCCCCCCCCCEEECCCCCEEEEECCCHHHHHCCCCCEEHHHH
FAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIEKNGTMAFDNAIIAYEPLWAV
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEECCEEEE
GTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCEE
GGVSLNATEFLSLCTIAMSA
CCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALRRPMVAGNWKMNGSAQLAQELFKKFATKLQDDSAEVVLCPPSIYLESVRQLLDENKE
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCHH
ALNGCLVRMGAQNLSQHDFGAYTGEISGQMLKDSGCRYVIIGHSERRRMYGETSVIVAEK
HHHHHHHHHCHHHCCCCCCCCCCCCCCCEEECCCCCEEEEECCCHHHHHCCCCCEEHHHH
FAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIEKNGTMAFDNAIIAYEPLWAV
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEECCEEEE
GTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCEE
GGVSLNATEFLSLCTIAMSA
CCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA