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The map label for this gene is rlmM

Identifier: 167624983

GI number: 167624983

Start: 3747157

End: 3748239

Strand: Reverse

Name: rlmM

Synonym: Shal_3070

Alternate gene names: 167624983

Gene position: 3748239-3747157 (Counterclockwise)

Preceding gene: 167624984

Following gene: 167624981

Centisome position: 71.71

GC content: 43.86

Gene sequence:

>1083_bases
ATGATAAACCTATTTTTATTTTGCCGTGCTGGTTACGAGAAAGATTGCGCTGCAGAGATCCAAGTGCGCGCGGCTGAGCT
CGACATTGGTGGATTTGTAAAAACCAACACCAATGATGCCTATGTCATTTTTCAGTGCTTTCAAGCCGGCGATGCTGAAG
TTTTGGCTAAAAACATTAGCTTGGACTCACTTATTTTTGCCAGACAGATGTTTGCCGCAAAAGAGTTACTAAAAGGCTTA
CCTGAACAAGATAGAATTAGCCCGATTGTTGAAGCCTTGGCTCAAGTACACAAAGCAGGCGAATTGCGCGTTGAAACGCC
TGACACGAACGAAGCGAAAGAGTTATCTAACTTCTGTCGTAAGTTCACTGTTCCGCTTAGACAGGCATTGAAAAAGTCGG
GCGCACTGCTTGAAAAAGAAAACCCAAAGCGTCCAATTATTCATGTGTGTTTTGTTGCATCTGGTCAAGCTTATGTTGGT
TTCTCACTGAGCAATAACAGTTCGCCTTATTTTATGGGGATCCCAAGACTTAAGATTGCTGCTGACGCGCCGAGTCGCTC
GACGCTTAAACTTGACGAAGCCTTTATTCACTTTATTCCTAAAGAAGAACAAGAAACTCGTCTAAGTAGTGGTATGAAGG
CGGTGGATCTTGGTGCTTGTCCTGGTGGTTGGACATATCAGCTTGTGAGACGTGGTATGTTTGTTGCGGCTGTCGATAAC
GGTCCAATGGATCAAGGTTTAATGGATACCGGACAGGTAAAACATTACCAAGCCGATGGATTTAGATTCGAGCCTCCAAG
AAAGAACATCACTTGGCTTGTGTGTGACATGATTGAAAAGCCATCTCGCGTAGCCGAGCTTATTGAAGCATGGGCGATTA
ATGGCTGGTTTAAAGAGTCAATCTTCAACTTAAAACTGCCTATGAAGGCACGTTATAAAGAAGTTTCGACAATTCTAGCG
ACGATGGAAGAGATCTTAAAAGAAAATGGTGTCGATGATTTCTCTATCGCGGCCAAGCATCTTTACCATGACCGTGATGA
AGTGACGGTTCATCTTTGCTTGAGACCGTCTCAACCTTGGTAA

Upstream 100 bases:

>100_bases
TCAAATACGCTGGCTGTTTTAAGCGCTATGCTTTTGAAGCCTTGTGTCATTTTTTAAAATGACACTTTGATTGATATTAT
TTTTATCTTCAGGAAATTCA

Downstream 100 bases:

>100_bases
TAGCTTAATTTTATTTAGCTTAATTTTGTCTAGCTTAGCCGAGCTTGGTTTTAAACTCGGTTAACGCAAGAGCATAAAAA
AGGCCTCATGTGAAAACATG

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNISLDSLIFARQMFAAKELLKGL
PEQDRISPIVEALAQVHKAGELRVETPDTNEAKELSNFCRKFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVG
FSLSNNSSPYFMGIPRLKIAADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKESIFNLKLPMKARYKEVSTILA
TMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW

Sequences:

>Translated_360_residues
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNISLDSLIFARQMFAAKELLKGL
PEQDRISPIVEALAQVHKAGELRVETPDTNEAKELSNFCRKFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVG
FSLSNNSSPYFMGIPRLKIAADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKESIFNLKLPMKARYKEVSTILA
TMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW
>Mature_360_residues
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNISLDSLIFARQMFAAKELLKGL
PEQDRISPIVEALAQVHKAGELRVETPDTNEAKELSNFCRKFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVG
FSLSNNSSPYFMGIPRLKIAADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKESIFNLKLPMKARYKEVSTILA
TMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=353, Percent_Identity=58.9235127478753, Blast_Score=437, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_SHEHH (B0TPH1)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001675277.1
- ProteinModelPortal:   B0TPH1
- SMR:   B0TPH1
- GeneID:   5904677
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_3070
- HOGENOM:   HBG681972
- OMA:   LYCRPGF
- ProtClustDB:   PRK11760
- BioCyc:   SHAL458817:SHAL_3070-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 40410; Mature: 40410

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNIS
CEEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEEEEECCCCHHHHHHCCC
LDSLIFARQMFAAKELLKGLPEQDRISPIVEALAQVHKAGELRVETPDTNEAKELSNFCR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVGFSLSNNSSPYFMGIPRLKIA
HHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEECCCEEEE
ADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
ECCCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHCCEEEEEECC
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKES
CCCCCCCCCCCCEEEEECCCEEECCCCCCCEEEEEHHHHCCHHHHHHHHHHHCCCHHHHH
IFNLKLPMKARYKEVSTILATMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW
HHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MINLFLFCRAGYEKDCAAEIQVRAAELDIGGFVKTNTNDAYVIFQCFQAGDAEVLAKNIS
CEEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEEEEECCCCHHHHHHCCC
LDSLIFARQMFAAKELLKGLPEQDRISPIVEALAQVHKAGELRVETPDTNEAKELSNFCR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQALKKSGALLEKENPKRPIIHVCFVASGQAYVGFSLSNNSSPYFMGIPRLKIA
HHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEECCCEEEE
ADAPSRSTLKLDEAFIHFIPKEEQETRLSSGMKAVDLGACPGGWTYQLVRRGMFVAAVDN
ECCCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHCCEEEEEECC
GPMDQGLMDTGQVKHYQADGFRFEPPRKNITWLVCDMIEKPSRVAELIEAWAINGWFKES
CCCCCCCCCCCCEEEEECCCEEECCCCCCCEEEEEHHHHCCHHHHHHHHHHHCCCHHHHH
IFNLKLPMKARYKEVSTILATMEEILKENGVDDFSIAAKHLYHDRDEVTVHLCLRPSQPW
HHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA