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The map label for this gene is cdsA [H]

Identifier: 167624890

GI number: 167624890

Start: 3620880

End: 3621737

Strand: Reverse

Name: cdsA [H]

Synonym: Shal_2976

Alternate gene names: 167624890

Gene position: 3621737-3620880 (Counterclockwise)

Preceding gene: 167624891

Following gene: 167624889

Centisome position: 69.29

GC content: 45.34

Gene sequence:

>858_bases
TTGCTAAAACAACGAATAATAACAGCAATATGGTTAATCCCCTTAGTTTTTGGTGCCATCTTCGGTTTACCGACTGAGTA
TTTTTCTTGGGCACTATTGGGAGTATTTTTAATCGCCGCTAAGGAGTGGGGGCGCATTATCGATAGTCGCTGTCAGATGA
CTCAGTGGAGTTTCACAGTGACTATTGGTGTTTTGCTAGCGGCCCTGAATATCTTGGTTCCAGCCGACGAGATTTGGTTA
CGAGGTATGATGCACCCGATATTTCTTGGGGTGATCCTTATCGGTGGCTTCTGGTGGTTTATCTCCTTTATCATGGTGTT
GTCTTTCCCTAAAAGCGCTCGCTTCTGGGAAAATAGCCACATGTTAAAATCTATGTTTGGCCAGTTAACGCTGATCCCAT
GTTTCGTTTCGCTCGTCTCGCTTAAGGCTCTGAGTACTCAAGCTTCACCTTATTACGGTGGCACCTTAGTATTGTTAGTG
ATGCTAGTCGTCTGGGCTACCGATTCTGGCGCCTATTTTGTAGGCAAGCGATTTGGTAAGCGTAAGTTGATGCCAAATGT
TAGCCCTGCTAAAACTATCGAAGGTCTGCTTGGCGGCCTGTTGACGACCATGATAGTGGTAGCGGGTATTATGTATTTCT
CTCCTGAGCAGGAGCTCGGTTTAGTTATCGCAGTAACCCTGTTTACGGCATTAGCCTCCGCAGTTGGTGACCTGTCTGAG
AGTATGTTTAAGCGAGTCGCAAAAATTAAAGACTCTGGCACTATCCTACCGGGTCACGGTGGCGTATTAGATAGAATCGA
TAGCCTAACGGCTGCTCTACCTGTATTCACATTAATCTATATAGCTTTTTGGATGTAA

Upstream 100 bases:

>100_bases
ACGCGATTGCTATTTTTGCTAATCGTCAGCGTCGATTCGGTTTGACAGGAACTCAAATCGATACCATCCGCTCTTTGTAA
TAATTAGTGAGGGAAGTTTT

Downstream 100 bases:

>100_bases
CTAAATGCAAAACATGGTGATTTTAGGCGCGACGGGCTCTATCGGTGCCAGCACCTTGAGTGTTGTAGCGTGTAATCCAG
AGCAATACAAGGTATATGCT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLKQRIITAIWLIPLVFGAIFGLPTEYFSWALLGVFLIAAKEWGRIIDSRCQMTQWSFTVTIGVLLAALNILVPADEIWL
RGMMHPIFLGVILIGGFWWFISFIMVLSFPKSARFWENSHMLKSMFGQLTLIPCFVSLVSLKALSTQASPYYGGTLVLLV
MLVVWATDSGAYFVGKRFGKRKLMPNVSPAKTIEGLLGGLLTTMIVVAGIMYFSPEQELGLVIAVTLFTALASAVGDLSE
SMFKRVAKIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM

Sequences:

>Translated_285_residues
MLKQRIITAIWLIPLVFGAIFGLPTEYFSWALLGVFLIAAKEWGRIIDSRCQMTQWSFTVTIGVLLAALNILVPADEIWL
RGMMHPIFLGVILIGGFWWFISFIMVLSFPKSARFWENSHMLKSMFGQLTLIPCFVSLVSLKALSTQASPYYGGTLVLLV
MLVVWATDSGAYFVGKRFGKRKLMPNVSPAKTIEGLLGGLLTTMIVVAGIMYFSPEQELGLVIAVTLFTALASAVGDLSE
SMFKRVAKIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM
>Mature_285_residues
MLKQRIITAIWLIPLVFGAIFGLPTEYFSWALLGVFLIAAKEWGRIIDSRCQMTQWSFTVTIGVLLAALNILVPADEIWL
RGMMHPIFLGVILIGGFWWFISFIMVLSFPKSARFWENSHMLKSMFGQLTLIPCFVSLVSLKALSTQASPYYGGTLVLLV
MLVVWATDSGAYFVGKRFGKRKLMPNVSPAKTIEGLLGGLLTTMIVVAGIMYFSPEQELGLVIAVTLFTALASAVGDLSE
SMFKRVAKIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=280, Percent_Identity=42.5, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787677, Length=113, Percent_Identity=45.1327433628319, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31455; Mature: 31455

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQRIITAIWLIPLVFGAIFGLPTEYFSWALLGVFLIAAKEWGRIIDSRCQMTQWSFTV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIGVLLAALNILVPADEIWLRGMMHPIFLGVILIGGFWWFISFIMVLSFPKSARFWENSH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MLKSMFGQLTLIPCFVSLVSLKALSTQASPYYGGTLVLLVMLVVWATDSGAYFVGKRFGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCC
RKLMPNVSPAKTIEGLLGGLLTTMIVVAGIMYFSPEQELGLVIAVTLFTALASAVGDLSE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMFKRVAKIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM
HHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLKQRIITAIWLIPLVFGAIFGLPTEYFSWALLGVFLIAAKEWGRIIDSRCQMTQWSFTV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIGVLLAALNILVPADEIWLRGMMHPIFLGVILIGGFWWFISFIMVLSFPKSARFWENSH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MLKSMFGQLTLIPCFVSLVSLKALSTQASPYYGGTLVLLVMLVVWATDSGAYFVGKRFGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCC
RKLMPNVSPAKTIEGLLGGLLTTMIVVAGIMYFSPEQELGLVIAVTLFTALASAVGDLSE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMFKRVAKIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM
HHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]