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The map label for this gene is etfA [H]

Identifier: 167624858

GI number: 167624858

Start: 3579124

End: 3580047

Strand: Reverse

Name: etfA [H]

Synonym: Shal_2944

Alternate gene names: 167624858

Gene position: 3580047-3579124 (Counterclockwise)

Preceding gene: 167624859

Following gene: 167624857

Centisome position: 68.49

GC content: 47.19

Gene sequence:

>924_bases
ATGGCAATTTTAGTATTAGCAGAACACGATAACGCCAGTCTAAAACTGGATACCGCTAAGGTCGTTGCATGTGCCGAAGC
CATCGGTGGGGATATAGACCTATTAGTTATCGGTCATAACTGTGGTTCAGTGGCAAGCGAAGCTCAAAAACTCAGTGGTG
TACGTAATGTCTTAGTGGCAGACGCGCCAGCATACGCGAATCATCTGGCTGATAGTGTATCTGAGTTGATGCTGGAAATT
GCATCCGATTACCAACATATTCTTGCCGCAGCTTCAAGCTTTGGTAAAGACGTCTTACCTCGCGTAGCAGCACTTTTAGA
TGTGTCTCAGCTTTCAGAAGTGATTGAGGTCGTCAGCAGTGACACATTCGTTCGCCCTATATACGCGGGTAACGGTTTAG
CGACAGTGCAGAGCTTAGATGATAAAAAAGTGATGACAGTGCGTTCTAGTGCGTTTGATGCAGTAGCAGCAGACGGTAGT
GCAGCACTAGTGACGCTTTCGCAAGCGTTTAGCTCACAGGTTGAGTTTGTTGCTCAAAGCCTGACTGAATCAGAGCGTCC
TGAGCTGGGTAGTGCATCAGTTGTAGTCGCTGGCGGTCGTGCTTTAGGCAATTGCGAGAACTTCGCTATGTTAGAGCAAC
TTGCTGACAAGCTTGATGGTGCGGTTGGTGCATCTCGTGCAGCGGTTGATGCAGGCTTTGTAGCAAATGATTTACAAGTG
GGTCAAACGGGTAAAATAGTTGCGCCTGACTTATATATTGCCGTCGGTATTTCGGGCGCGATTCAGCACCTTGCTGGTAT
GAAAGACTCAAAGGTGATTGTGGCCATCAACAAAGATCCTGAAGCGCCGATTTTCCAGATAGCAGATTACGGTCTTGAAG
CCGATCTATTTGAAGCGGTACCAGAATTATTAGCCAAGCTTTAA

Upstream 100 bases:

>100_bases
TTATTAAAGTGACACCACCAGCCCAGCGCAGTGGTGGTGTGATGGTAGCGTCTGTAGAAGAGTTGGTTGAAAAGTTAAAG
AATGAAGCGAAGGTGATCTA

Downstream 100 bases:

>100_bases
TGTAACCCTTAAAGCCAGAACAACGCTTACACAGTGTGGAAATGTTATGCACTGATAGTTGAGTTGTTAATGGCTATAAG
TTGCATTTGGTATTATTGGT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAILVLAEHDNASLKLDTAKVVACAEAIGGDIDLLVIGHNCGSVASEAQKLSGVRNVLVADAPAYANHLADSVSELMLEI
ASDYQHILAAASSFGKDVLPRVAALLDVSQLSEVIEVVSSDTFVRPIYAGNGLATVQSLDDKKVMTVRSSAFDAVAADGS
AALVTLSQAFSSQVEFVAQSLTESERPELGSASVVVAGGRALGNCENFAMLEQLADKLDGAVGASRAAVDAGFVANDLQV
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAVPELLAKL

Sequences:

>Translated_307_residues
MAILVLAEHDNASLKLDTAKVVACAEAIGGDIDLLVIGHNCGSVASEAQKLSGVRNVLVADAPAYANHLADSVSELMLEI
ASDYQHILAAASSFGKDVLPRVAALLDVSQLSEVIEVVSSDTFVRPIYAGNGLATVQSLDDKKVMTVRSSAFDAVAADGS
AALVTLSQAFSSQVEFVAQSLTESERPELGSASVVVAGGRALGNCENFAMLEQLADKLDGAVGASRAAVDAGFVANDLQV
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAVPELLAKL
>Mature_306_residues
AILVLAEHDNASLKLDTAKVVACAEAIGGDIDLLVIGHNCGSVASEAQKLSGVRNVLVADAPAYANHLADSVSELMLEIA
SDYQHILAAASSFGKDVLPRVAALLDVSQLSEVIEVVSSDTFVRPIYAGNGLATVQSLDDKKVMTVRSSAFDAVAADGSA
ALVTLSQAFSSQVEFVAQSLTESERPELGSASVVVAGGRALGNCENFAMLEQLADKLDGAVGASRAAVDAGFVANDLQVG
QTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAVPELLAKL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=55.5555555555556, Blast_Score=321, Evalue=5e-88,
Organism=Homo sapiens, GI189181759, Length=265, Percent_Identity=58.1132075471698, Blast_Score=293, Evalue=2e-79,
Organism=Escherichia coli, GI1786226, Length=168, Percent_Identity=38.6904761904762, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787990, Length=234, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082157, Length=274, Percent_Identity=28.4671532846715, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=310, Percent_Identity=52.258064516129, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6325261, Length=247, Percent_Identity=52.6315789473684, Blast_Score=252, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=58.8424437299035, Blast_Score=344, Evalue=5e-95,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=58.8424437299035, Blast_Score=344, Evalue=5e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31691; Mature: 31560

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLAEHDNASLKLDTAKVVACAEAIGGDIDLLVIGHNCGSVASEAQKLSGVRNVLVA
CEEEEEEECCCCEEEECHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEE
DAPAYANHLADSVSELMLEIASDYQHILAAASSFGKDVLPRVAALLDVSQLSEVIEVVSS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGNGLATVQSLDDKKVMTVRSSAFDAVAADGSAALVTLSQAFSSQVEFVAQS
CCEEEEEEECCCEEEHHCCCCCCEEEEHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHH
LTESERPELGSASVVVAGGRALGNCENFAMLEQLADKLDGAVGASRAAVDAGFVANDLQV
HHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCEECCCEE
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAV
CCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCHHHHHHH
PELLAKL
HHHHHCC
>Mature Secondary Structure 
AILVLAEHDNASLKLDTAKVVACAEAIGGDIDLLVIGHNCGSVASEAQKLSGVRNVLVA
EEEEEEECCCCEEEECHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEE
DAPAYANHLADSVSELMLEIASDYQHILAAASSFGKDVLPRVAALLDVSQLSEVIEVVSS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGNGLATVQSLDDKKVMTVRSSAFDAVAADGSAALVTLSQAFSSQVEFVAQS
CCEEEEEEECCCEEEHHCCCCCCEEEEHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHH
LTESERPELGSASVVVAGGRALGNCENFAMLEQLADKLDGAVGASRAAVDAGFVANDLQV
HHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCEECCCEE
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAV
CCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCHHHHHHH
PELLAKL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]