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The map label for this gene is yqjI [H]

Identifier: 167624813

GI number: 167624813

Start: 3522959

End: 3524506

Strand: Reverse

Name: yqjI [H]

Synonym: Shal_2899

Alternate gene names: 167624813

Gene position: 3524506-3522959 (Counterclockwise)

Preceding gene: 167624814

Following gene: 167624811

Centisome position: 67.43

GC content: 47.48

Gene sequence:

>1548_bases
ATGAAGAACCAATCAAATCTTTACGATATCGGTGTTATTGGCTTGGGCGTAATGGGTAAGAACCTTGCACTTAATATAGC
CGACAACCAATATCGCGTCGCTGCATTTGACCTTGATGAACTCAAGGTGCAAGACACTGTTGCACAAGAAGAACTAGAGC
GTAAGCGATACCTAAAACAGATAACTGAGCCACGAATAGAAGGCTGTAACAATCTTTCTGAAATGTTATCTAAATTAGAA
AAGCCCCGCGTACTGCTTCTATCTGTACCGGCAGGAGCTCCTGTCGACGGTGTTTGTCAGTCTCTAATTGAAGCCGGGAT
CGAGAATGATGATATCGTGATTGATACAGGTAACAGCTTATGGACGGATACGGTTGAGCGCGAGAAGCGCTACGCCGACA
ATTTTCTTTTCTTTAGCTGCGCGGTATCAGGTGGTGAAGTCGGTGCGCGTTTTGGTCCATCTCTGATGCCAAGTGGCAGC
TTAAAAGCCTGGAATAGAATTGAGCCAATATGGCAAGCAATTGCCGCTAAAGTCGATGCTAAAACAGGTTTGCCTATCGA
GCGTTTTGAGCCGGGAAACCCCGTGAAAGAAGGCGAGCCTTGTACCACCTATATTGGTCCTGCGGGTTCTGGTCATTACG
TTAAAATGGTACATAACGGTATTGAATATGCTGACATGCAACTTATCTGCGAGGCTTATCAGCTATTAAATCAGGGCTTA
GGATTATCACCGAGTGAAGTGGGTGATGTGTTTGAACGGTGGGATCAAGGGATCTTAAACAGCTACTTGATGCAGATCAG
CGCCGATGTGCTCAAACAAGCAGACCCATTAACCGGGGCGCCACTGGTCGATATGATCTTGGATAAGGCGGGGCAAAAAG
GCACGGGTCTTTGGACTGCGGTAAGCAGTTTACAGATAGGCTGCCCAGCACCCACCATCGCTGAAGCGGTTTATGCCCGC
GCAGTCAGTACTCAAAAAGCTCAAAGACAGCAACTTAGCCAACAGTTATCCGGGCCAAGCGAAGCGCTGTTGGCCACGAT
TAACCGTGGTGAAAAGCAGACATTTATCGCTCAGCTTGAAAATGCGCTCTATTGCGCCAAAGTGTCTTGCTACGCCCAAG
GTTTTCAGTTGATGGCTATGCAAGCTAAGGAGCAAGCTTGGCAGTTGGATTTTGCTGAAATCGCTAAAATTTGGCGGGCC
GGCTGTATTATCCGCGCCACTTTCTTGCAATCGATCACCAAGGCATATCAGCAAGATAGTGAGCTTGAAAACCTGCTGAT
GGCAGACTCTTTTGCTAAAGCTTTGTCTGAAAAACAACAAGATTGGAGAGAAGCCGTATCGCAAGCCGTACTGAGTGGTA
TACCCGCGCCTTGTATCAGTTCGGCTTTAGCTTATTACGACAGTTATCGCTGTGAAACCTTGCCAGCGAGTTTACTACAA
GGGCAGCGAGACTTTTTCGGTGCCCATACTTTTGAGCGAACCGACAAGCCAGCGGGTGAGAAGTATCACCTGAACTGGAG
TGGAGATCGCAGTTTACATAAGATGTAA

Upstream 100 bases:

>100_bases
AACAAAATTAAACCCGTCACTCCAATAGGCAGCACCAGCTATTGTTGCCTATATAAAATAATAGACGGGTAATTCTCTGT
GACCTACGGAAGAAATCTAC

Downstream 100 bases:

>100_bases
TTCGGTGTCTTTACTCTGAGCTGTACATACAAAAAAGCCTATCAATCGATAGGCTTTTTTATTGCTCATTAGAGGCTAGC
GAATGGCTAGACTAGGTCAC

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKNQSNLYDIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELERKRYLKQITEPRIEGCNNLSEMLSKLE
KPRVLLLSVPAGAPVDGVCQSLIEAGIENDDIVIDTGNSLWTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGS
LKAWNRIEPIWQAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
GLSPSEVGDVFERWDQGILNSYLMQISADVLKQADPLTGAPLVDMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYAR
AVSTQKAQRQQLSQQLSGPSEALLATINRGEKQTFIAQLENALYCAKVSCYAQGFQLMAMQAKEQAWQLDFAEIAKIWRA
GCIIRATFLQSITKAYQQDSELENLLMADSFAKALSEKQQDWREAVSQAVLSGIPAPCISSALAYYDSYRCETLPASLLQ
GQRDFFGAHTFERTDKPAGEKYHLNWSGDRSLHKM

Sequences:

>Translated_515_residues
MKNQSNLYDIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELERKRYLKQITEPRIEGCNNLSEMLSKLE
KPRVLLLSVPAGAPVDGVCQSLIEAGIENDDIVIDTGNSLWTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGS
LKAWNRIEPIWQAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
GLSPSEVGDVFERWDQGILNSYLMQISADVLKQADPLTGAPLVDMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYAR
AVSTQKAQRQQLSQQLSGPSEALLATINRGEKQTFIAQLENALYCAKVSCYAQGFQLMAMQAKEQAWQLDFAEIAKIWRA
GCIIRATFLQSITKAYQQDSELENLLMADSFAKALSEKQQDWREAVSQAVLSGIPAPCISSALAYYDSYRCETLPASLLQ
GQRDFFGAHTFERTDKPAGEKYHLNWSGDRSLHKM
>Mature_515_residues
MKNQSNLYDIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELERKRYLKQITEPRIEGCNNLSEMLSKLE
KPRVLLLSVPAGAPVDGVCQSLIEAGIENDDIVIDTGNSLWTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGS
LKAWNRIEPIWQAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
GLSPSEVGDVFERWDQGILNSYLMQISADVLKQADPLTGAPLVDMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYAR
AVSTQKAQRQQLSQQLSGPSEALLATINRGEKQTFIAQLENALYCAKVSCYAQGFQLMAMQAKEQAWQLDFAEIAKIWRA
GCIIRATFLQSITKAYQQDSELENLLMADSFAKALSEKQQDWREAVSQAVLSGIPAPCISSALAYYDSYRCETLPASLLQ
GQRDFFGAHTFERTDKPAGEKYHLNWSGDRSLHKM

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=501, Percent_Identity=45.7085828343313, Blast_Score=421, Evalue=1e-118,
Organism=Escherichia coli, GI1788341, Length=498, Percent_Identity=44.578313253012, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17542558, Length=501, Percent_Identity=45.7085828343313, Blast_Score=433, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321695, Length=507, Percent_Identity=45.1676528599605, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321977, Length=507, Percent_Identity=44.9704142011834, Blast_Score=425, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24639279, Length=502, Percent_Identity=45.0199203187251, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 56628; Mature: 56628

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQSNLYDIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELERKRYLKQ
CCCCCCEEEEHHHHHCCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
ITEPRIEGCNNLSEMLSKLEKPRVLLLSVPAGAPVDGVCQSLIEAGIENDDIVIDTGNSL
HCCHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCH
WTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGSLKAWNRIEPIWQAIAAKVDA
HHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
KTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHCCC
GLSPSEVGDVFERWDQGILNSYLMQISADVLKQADPLTGAPLVDMILDKAGQKGTGLWTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHH
VSSLQIGCPAPTIAEAVYARAVSTQKAQRQQLSQQLSGPSEALLATINRGEKQTFIAQLE
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
NALYCAKVSCYAQGFQLMAMQAKEQAWQLDFAEIAKIWRAGCIIRATFLQSITKAYQQDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELENLLMADSFAKALSEKQQDWREAVSQAVLSGIPAPCISSALAYYDSYRCETLPASLLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHCCHHHHC
GQRDFFGAHTFERTDKPAGEKYHLNWSGDRSLHKM
CCHHHHCCCCHHCCCCCCCCEEEEECCCCCHHCCC
>Mature Secondary Structure
MKNQSNLYDIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELERKRYLKQ
CCCCCCEEEEHHHHHCCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
ITEPRIEGCNNLSEMLSKLEKPRVLLLSVPAGAPVDGVCQSLIEAGIENDDIVIDTGNSL
HCCHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCH
WTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGSLKAWNRIEPIWQAIAAKVDA
HHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
KTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHCCC
GLSPSEVGDVFERWDQGILNSYLMQISADVLKQADPLTGAPLVDMILDKAGQKGTGLWTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHH
VSSLQIGCPAPTIAEAVYARAVSTQKAQRQQLSQQLSGPSEALLATINRGEKQTFIAQLE
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
NALYCAKVSCYAQGFQLMAMQAKEQAWQLDFAEIAKIWRAGCIIRATFLQSITKAYQQDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELENLLMADSFAKALSEKQQDWREAVSQAVLSGIPAPCISSALAYYDSYRCETLPASLLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHCCHHHHC
GQRDFFGAHTFERTDKPAGEKYHLNWSGDRSLHKM
CCHHHHCCCCHHCCCCCCCCEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]