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The map label for this gene is tesB [H]

Identifier: 167624810

GI number: 167624810

Start: 3519760

End: 3520626

Strand: Reverse

Name: tesB [H]

Synonym: Shal_2896

Alternate gene names: 167624810

Gene position: 3520626-3519760 (Counterclockwise)

Preceding gene: 167624811

Following gene: 167624809

Centisome position: 67.36

GC content: 48.1

Gene sequence:

>867_bases
ATGAGCCAAGTATTAGATGATCTTTTAGCGTTACTTTCGTTAGAGCGGATCGAAGTGGGGCTGTTTCGTGGTCAAAGCCA
AGATCTAGGTTTTGGTCACGTCTTTGGTGGTCAAGTCATGGGGCAAGCCTTAAGTGCGGCTAAGCAGACTGTCAGTCCTG
ACCGTAAGGTGCACTCTTTACACTCCTATTTTTTACGTGCCGGCGATGAGAAACTACCTATTGTGTATGATGTTGAAATC
ATGCGTGATGGTGGCAGCTTCAGTGCAAGAAGAGTTAAAGCCATCCAGAAAGGCCGTCCCATCTTCTATATGACCTGCTC
TTTTCAAACTGCTGAAGAAGGCTATGACCATCAAGCCGTGATGCCTGATGTGCCGGGACCCGATGGCCTGCTTAATCAAC
AAGAGTTAGCGATGACCCTTAGAGATAAAGTGCCGTCTAAAGTGCTAGAAAAGTTTATGGCCGATACGCCAATTGAGATG
CGCTTAGTCAACCCAAGTGATCCGATCGCACCGGCAGCTCGGGAGCCTATTCGGCATGTGTGGATCCGCGCTAATGGTAA
AGTGCCTGATAATATGTCTGTGCACGATTATTTGCTCGCCTATGCGTCGGACTTTAACTTTTTAGTTACGGCAGCTCAGC
CACACGGGGTTTCATTTTTAACACCCGGTATGCGTATGGCCACCATAGATCATGCAATGTGGTTTCACCGCCCATTCGAC
TTGAGCCAGTGGCTTTTGTATACCATAGACAGTCCCAATGCCAGCGGTGGTCGAGGTTTTGTCAGAGGGCAGTTTTTTAA
TCAGCAAGGCGAGCTCGTTGCATCAGCGACACAAGAGGGGCTTATTCGGATGATGAAAACATCATAA

Upstream 100 bases:

>100_bases
GCCGTATCGTATTAGAGTAGTGCTAGATTGAGTAGAACTGGCGAGACTAGGGGATCTTGAGTTAAGCTTATGGCCATAAT
TAGCTGATTTTTAGGTTGCA

Downstream 100 bases:

>100_bases
TGCCGCAACTGTTTGTTTATATTTTGTATTTAGGGTTTAAATCATGATCTCATTATTGAAAAAAAGTGTTGTACTGCTCT
GTATGTTGGTATTAACAGCT

Product: acyl-CoA thioesterase II

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSQVLDDLLALLSLERIEVGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVSPDRKVHSLHSYFLRAGDEKLPIVYDVEI
MRDGGSFSARRVKAIQKGRPIFYMTCSFQTAEEGYDHQAVMPDVPGPDGLLNQQELAMTLRDKVPSKVLEKFMADTPIEM
RLVNPSDPIAPAAREPIRHVWIRANGKVPDNMSVHDYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAMWFHRPFD
LSQWLLYTIDSPNASGGRGFVRGQFFNQQGELVASATQEGLIRMMKTS

Sequences:

>Translated_288_residues
MSQVLDDLLALLSLERIEVGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVSPDRKVHSLHSYFLRAGDEKLPIVYDVEI
MRDGGSFSARRVKAIQKGRPIFYMTCSFQTAEEGYDHQAVMPDVPGPDGLLNQQELAMTLRDKVPSKVLEKFMADTPIEM
RLVNPSDPIAPAAREPIRHVWIRANGKVPDNMSVHDYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAMWFHRPFD
LSQWLLYTIDSPNASGGRGFVRGQFFNQQGELVASATQEGLIRMMKTS
>Mature_287_residues
SQVLDDLLALLSLERIEVGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVSPDRKVHSLHSYFLRAGDEKLPIVYDVEIM
RDGGSFSARRVKAIQKGRPIFYMTCSFQTAEEGYDHQAVMPDVPGPDGLLNQQELAMTLRDKVPSKVLEKFMADTPIEMR
LVNPSDPIAPAAREPIRHVWIRANGKVPDNMSVHDYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAMWFHRPFDL
SQWLLYTIDSPNASGGRGFVRGQFFNQQGELVASATQEGLIRMMKTS

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=290, Percent_Identity=43.448275862069, Blast_Score=218, Evalue=7e-57,
Organism=Escherichia coli, GI1786657, Length=283, Percent_Identity=60.7773851590106, Blast_Score=356, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI71988741, Length=294, Percent_Identity=35.7142857142857, Blast_Score=182, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17531889, Length=278, Percent_Identity=35.2517985611511, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI115532456, Length=278, Percent_Identity=35.2517985611511, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17531885, Length=278, Percent_Identity=35.2517985611511, Blast_Score=163, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17558508, Length=319, Percent_Identity=35.1097178683386, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI212645202, Length=276, Percent_Identity=32.6086956521739, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71982224, Length=299, Percent_Identity=27.4247491638796, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32072; Mature: 31941

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVLDDLLALLSLERIEVGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVSPDRKVHSL
CHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
HSYFLRAGDEKLPIVYDVEIMRDGGSFSARRVKAIQKGRPIFYMTCSFQTAEEGYDHQAV
HHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCHHCCCCCCCC
MPDVPGPDGLLNQQELAMTLRDKVPSKVLEKFMADTPIEMRLVNPSDPIAPAAREPIRHV
CCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCEEE
WIRANGKVPDNMSVHDYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAMWFHRPFD
EEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEECCCCEEHHHHHHHHHCCCCC
LSQWLLYTIDSPNASGGRGFVRGQFFNQQGELVASATQEGLIRMMKTS
CCCEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQVLDDLLALLSLERIEVGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVSPDRKVHSL
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
HSYFLRAGDEKLPIVYDVEIMRDGGSFSARRVKAIQKGRPIFYMTCSFQTAEEGYDHQAV
HHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCHHCCCCCCCC
MPDVPGPDGLLNQQELAMTLRDKVPSKVLEKFMADTPIEMRLVNPSDPIAPAAREPIRHV
CCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCEEE
WIRANGKVPDNMSVHDYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAMWFHRPFD
EEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEECCCCEEHHHHHHHHHCCCCC
LSQWLLYTIDSPNASGGRGFVRGQFFNQQGELVASATQEGLIRMMKTS
CCCEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]