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The map label for this gene is atoB [H]

Identifier: 167624792

GI number: 167624792

Start: 3499267

End: 3500457

Strand: Reverse

Name: atoB [H]

Synonym: Shal_2878

Alternate gene names: 167624792

Gene position: 3500457-3499267 (Counterclockwise)

Preceding gene: 167624798

Following gene: 167624791

Centisome position: 66.97

GC content: 52.64

Gene sequence:

>1191_bases
ATGAGTTCAGTTCAGTCAAACCAAGATATTGTTATTGTTGCGGCAAAGCGCACCCCAATGGGGGGATTTCAAGGTGCATT
GTCCACTGTGGCCTCACCAACATTAGCAGCAACGGCGATTAAGGGCTTGATGCAACAAACAGATCTTGCAGGCGAACAGA
TCGACGAAGTCTTGATGGGTTGTGTACTGCCGGCAGGCTTAGGTCAGGCGCCAGCAAGGCAAGCCACATTAGGCGCTGAG
TTGCCACTATCGGTAGCTGCAACCACGGTTAATAAGGTGTGTGGCTCGGGAATGAAAACCGTGATGCTAGCTCATGATTT
AATTAAAGCGGGTAGTGCAAATATTGTGATTGCCGGTGGTATGGAAAGCATGAGCCAAGCGCCTTACTTGTTAGATAAGG
CCCGCAGTGGCATGCGCATGGGACATGGCAAGGTGATGGATCATATGTTCCTCGACGGTCTCGAAGATGCCTACACTGGC
GGCGCCATGGGGACATTTGCACAAGACACCGCCAACGACTTTAAACTAACCCGTGAGCAGATGGACAGTTTTGCATTGAG
CTCACTCGAAAAAGCCAATGCCGCTATCGAATCGGGAGCATTTAGCGATGAGATCACCCCTGTCACCGTGTCGAATCGCC
GCGGTGATACCGTAGTCGATACCGATGAGCAACCCGGTAATGCGCGCCCAGATAAAATTCCTACCCTGCGACCAGCCTTT
GCTAAAAACGGCACGATTACCGCCGCCAACTCAAGCTCAATCTCCGATGGCGCAGCCGCACTGATGCTAATGAGCCGCGA
GCAAGCAAATGACTTAGGGCTTGATGTGCTAGCCACCATTAAAGGTCACGCCACCCACGCGCAAGAGCCGTCGATGTTTA
CCACCGCGCCAGTGGCGGCTATGAATAAGCTGCTCGAAAAAGTGAGCTGGAGTAAGGATGAGGTGGACCTTTATGAGATC
AACGAAGCCTTCGCCATGGTGACCATGTTGGCTATTTCCGAGCTTGGACTCGACGCCAACAAGGTTAATGTTAATGGTGG
CGCCTGCGCGCTTGGGCATCCCATTGGCTGCTCGGGCGCACGTTTACTCGTCACCTTGATTTATGCCCTAAAAGCCCGCG
GTCTTAAGCGCGGCGTGGCATCACTTTGTATTGGCGGTGGTGAAGCAACAGCGATGGCGATTGAGCTATAA

Upstream 100 bases:

>100_bases
AGCCTGAGAACAGTCAATAAGCAAAGTTGCTGAACCCTACAGCGAGAGCGGCTTTGGACTACTTCTAATAAAGGTTAACT
AGCATATTACCGGAGTTACT

Downstream 100 bases:

>100_bases
GCCTCCTTGGTAAAGATAAATGCAAGACAAACCACAGTATTCAACAAGACAGGATTGAACTTAGGACCATGGCCTTAACA
GCAGTTTTGCTGTTAAGGCC

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSSVQSNQDIVIVAAKRTPMGGFQGALSTVASPTLAATAIKGLMQQTDLAGEQIDEVLMGCVLPAGLGQAPARQATLGAE
LPLSVAATTVNKVCGSGMKTVMLAHDLIKAGSANIVIAGGMESMSQAPYLLDKARSGMRMGHGKVMDHMFLDGLEDAYTG
GAMGTFAQDTANDFKLTREQMDSFALSSLEKANAAIESGAFSDEITPVTVSNRRGDTVVDTDEQPGNARPDKIPTLRPAF
AKNGTITAANSSSISDGAAALMLMSREQANDLGLDVLATIKGHATHAQEPSMFTTAPVAAMNKLLEKVSWSKDEVDLYEI
NEAFAMVTMLAISELGLDANKVNVNGGACALGHPIGCSGARLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL

Sequences:

>Translated_396_residues
MSSVQSNQDIVIVAAKRTPMGGFQGALSTVASPTLAATAIKGLMQQTDLAGEQIDEVLMGCVLPAGLGQAPARQATLGAE
LPLSVAATTVNKVCGSGMKTVMLAHDLIKAGSANIVIAGGMESMSQAPYLLDKARSGMRMGHGKVMDHMFLDGLEDAYTG
GAMGTFAQDTANDFKLTREQMDSFALSSLEKANAAIESGAFSDEITPVTVSNRRGDTVVDTDEQPGNARPDKIPTLRPAF
AKNGTITAANSSSISDGAAALMLMSREQANDLGLDVLATIKGHATHAQEPSMFTTAPVAAMNKLLEKVSWSKDEVDLYEI
NEAFAMVTMLAISELGLDANKVNVNGGACALGHPIGCSGARLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL
>Mature_395_residues
SSVQSNQDIVIVAAKRTPMGGFQGALSTVASPTLAATAIKGLMQQTDLAGEQIDEVLMGCVLPAGLGQAPARQATLGAEL
PLSVAATTVNKVCGSGMKTVMLAHDLIKAGSANIVIAGGMESMSQAPYLLDKARSGMRMGHGKVMDHMFLDGLEDAYTGG
AMGTFAQDTANDFKLTREQMDSFALSSLEKANAAIESGAFSDEITPVTVSNRRGDTVVDTDEQPGNARPDKIPTLRPAFA
KNGTITAANSSSISDGAAALMLMSREQANDLGLDVLATIKGHATHAQEPSMFTTAPVAAMNKLLEKVSWSKDEVDLYEIN
EAFAMVTMLAISELGLDANKVNVNGGACALGHPIGCSGARLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI4557237, Length=390, Percent_Identity=43.8461538461538, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI148539872, Length=389, Percent_Identity=43.9588688946015, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI167614485, Length=391, Percent_Identity=36.0613810741688, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI4501853, Length=406, Percent_Identity=36.2068965517241, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4504327, Length=426, Percent_Identity=29.5774647887324, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI194353979, Length=83, Percent_Identity=50.6024096385542, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI87082165, Length=389, Percent_Identity=46.0154241645244, Blast_Score=347, Evalue=6e-97,
Organism=Escherichia coli, GI1788554, Length=390, Percent_Identity=50, Blast_Score=337, Evalue=8e-94,
Organism=Escherichia coli, GI1787663, Length=392, Percent_Identity=39.5408163265306, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI48994986, Length=403, Percent_Identity=37.468982630273, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1788683, Length=402, Percent_Identity=28.1094527363184, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25147385, Length=394, Percent_Identity=42.8934010152284, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17535921, Length=392, Percent_Identity=40.3061224489796, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI133906874, Length=387, Percent_Identity=35.4005167958656, Blast_Score=258, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17535917, Length=398, Percent_Identity=35.1758793969849, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17551802, Length=423, Percent_Identity=29.5508274231678, Blast_Score=164, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6325229, Length=395, Percent_Identity=46.5822784810127, Blast_Score=335, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6322031, Length=389, Percent_Identity=35.2185089974293, Blast_Score=205, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24655093, Length=388, Percent_Identity=46.1340206185567, Blast_Score=352, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24640423, Length=389, Percent_Identity=43.4447300771208, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17648125, Length=397, Percent_Identity=36.7758186397985, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI17137578, Length=426, Percent_Identity=31.2206572769953, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41021; Mature: 40889

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00098 THIOLASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVQSNQDIVIVAAKRTPMGGFQGALSTVASPTLAATAIKGLMQQTDLAGEQIDEVLMG
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
CVLPAGLGQAPARQATLGAELPLSVAATTVNKVCGSGMKTVMLAHDLIKAGSANIVIAGG
HHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECC
MESMSQAPYLLDKARSGMRMGHGKVMDHMFLDGLEDAYTGGAMGTFAQDTANDFKLTREQ
HHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCHHHCHHHHHHHHHH
MDSFALSSLEKANAAIESGAFSDEITPVTVSNRRGDTVVDTDEQPGNARPDKIPTLRPAF
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCHH
AKNGTITAANSSSISDGAAALMLMSREQANDLGLDVLATIKGHATHAQEPSMFTTAPVAA
CCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEHHHHHH
MNKLLEKVSWSKDEVDLYEINEAFAMVTMLAISELGLDANKVNVNGGACALGHPIGCSGA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCCHH
RLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure 
SSVQSNQDIVIVAAKRTPMGGFQGALSTVASPTLAATAIKGLMQQTDLAGEQIDEVLMG
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
CVLPAGLGQAPARQATLGAELPLSVAATTVNKVCGSGMKTVMLAHDLIKAGSANIVIAGG
HHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECC
MESMSQAPYLLDKARSGMRMGHGKVMDHMFLDGLEDAYTGGAMGTFAQDTANDFKLTREQ
HHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCHHHCHHHHHHHHHH
MDSFALSSLEKANAAIESGAFSDEITPVTVSNRRGDTVVDTDEQPGNARPDKIPTLRPAF
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCHH
AKNGTITAANSSSISDGAAALMLMSREQANDLGLDVLATIKGHATHAQEPSMFTTAPVAA
CCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEHHHHHH
MNKLLEKVSWSKDEVDLYEINEAFAMVTMLAISELGLDANKVNVNGGACALGHPIGCSGA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCCHH
RLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]