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The map label for this gene is apbE [H]

Identifier: 167624762

GI number: 167624762

Start: 3461233

End: 3462249

Strand: Reverse

Name: apbE [H]

Synonym: Shal_2846

Alternate gene names: 167624762

Gene position: 3462249-3461233 (Counterclockwise)

Preceding gene: 167624763

Following gene: 167624756

Centisome position: 66.24

GC content: 42.38

Gene sequence:

>1017_bases
ATGAGAAAACTAAAGATAGTTTGTTTAATGTTATTGTTACTCGCTCACAAAGTCTCAGCTGAATCGAGCCATATCCAGAT
ACATGGAAATACGATGGGGACGACATATAGTCTAACGCTTGATACGGCTGATATATCGTTATCTGAATTAGAGTTACAGA
TTGCAGTGGAACAAGAGCTCAATAAGGTCAATAACGGCTTGTCTATTTTTAGAGCAGAGTCAGAGATCTCTAAACTTAAT
CTTAACCATGGGCGGCAAGCTATCGAGATATCTCAACAGCTATGGGACGTTCTCGCTATTTCAAAACAAGTGTCGCAGCA
AACTGAGGGTGCGTTAGATATCACCTTGGAGCCAGTCATCGAGTTTTGGGGCTTTGGTGTTAAGGCGAGAGATCTCAAAG
GGAAAAACCGTGGTCAATTAGAATATGCACGTTCAAAAACAGGCATGGATGGATATGTTTTAGATAATGGGATGATTGTT
AAAGTTATTCCAGATCTAGCGATTAACCCCTCTGCTGTAGCAAAAGGTTACGGAGTCGATAGAGTCGCCAACGTATTGGA
TGACTTAGGAATTGCCAACTATTTAGTAGAGATTGGTGGTGAGCTGCGCGCCAAAGGCGTTGCTGCAGACGGTCATTTTT
GGAATATCGCCATATTGCGTCCTGAAAAGTTTAGTATGCAGATCCAAGAGGTTGTTAGCCTTAATAATATGGCTATAGCC
ACATCTGGAAGCTACGTTAATTACCTCGAAAGCGGTGAAAGCCAGCTGAGCCATATCATTAATCCCAATACCGGTATGCC
CGTTAATAATAGTGTCGTTTCTGCCACAGTACTGCATAAGCAATGCGCTGTTGCCGATGCTTTTGCTACCGCTCTAATGG
TGTTAGATGTGGAACGTTCGTTGCAAATTGCCGATAGTTTAGGACTTGCAGTGATGTTAATTGAGCAAACTGATAAGGGA
TCTGTGACTCATTTTAGCAGAGGCATTTTCCGATACTTACCCAATAAGGAGCCTTGA

Upstream 100 bases:

>100_bases
TTTGTGATAGCGCTTAACGTAAATGCCGCTCACGACAGTGAGCGGCATTTTTTTGCTTATTAAATAGATGATAGCTGTTG
GATTTTCCTCTAGGTGCTGT

Downstream 100 bases:

>100_bases
TACATGATGGATTTTGATCAGGTATTGCGTAAAGTCGCTGGCTTCAGCGCCCTTGTTCTGGTTTTTTGTGGTTTAACGTT
AGGCTTGTTAATTACGTCCG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRKLKIVCLMLLLLAHKVSAESSHIQIHGNTMGTTYSLTLDTADISLSELELQIAVEQELNKVNNGLSIFRAESEISKLN
LNHGRQAIEISQQLWDVLAISKQVSQQTEGALDITLEPVIEFWGFGVKARDLKGKNRGQLEYARSKTGMDGYVLDNGMIV
KVIPDLAINPSAVAKGYGVDRVANVLDDLGIANYLVEIGGELRAKGVAADGHFWNIAILRPEKFSMQIQEVVSLNNMAIA
TSGSYVNYLESGESQLSHIINPNTGMPVNNSVVSATVLHKQCAVADAFATALMVLDVERSLQIADSLGLAVMLIEQTDKG
SVTHFSRGIFRYLPNKEP

Sequences:

>Translated_338_residues
MRKLKIVCLMLLLLAHKVSAESSHIQIHGNTMGTTYSLTLDTADISLSELELQIAVEQELNKVNNGLSIFRAESEISKLN
LNHGRQAIEISQQLWDVLAISKQVSQQTEGALDITLEPVIEFWGFGVKARDLKGKNRGQLEYARSKTGMDGYVLDNGMIV
KVIPDLAINPSAVAKGYGVDRVANVLDDLGIANYLVEIGGELRAKGVAADGHFWNIAILRPEKFSMQIQEVVSLNNMAIA
TSGSYVNYLESGESQLSHIINPNTGMPVNNSVVSATVLHKQCAVADAFATALMVLDVERSLQIADSLGLAVMLIEQTDKG
SVTHFSRGIFRYLPNKEP
>Mature_338_residues
MRKLKIVCLMLLLLAHKVSAESSHIQIHGNTMGTTYSLTLDTADISLSELELQIAVEQELNKVNNGLSIFRAESEISKLN
LNHGRQAIEISQQLWDVLAISKQVSQQTEGALDITLEPVIEFWGFGVKARDLKGKNRGQLEYARSKTGMDGYVLDNGMIV
KVIPDLAINPSAVAKGYGVDRVANVLDDLGIANYLVEIGGELRAKGVAADGHFWNIAILRPEKFSMQIQEVVSLNNMAIA
TSGSYVNYLESGESQLSHIINPNTGMPVNNSVVSATVLHKQCAVADAFATALMVLDVERSLQIADSLGLAVMLIEQTDKG
SVTHFSRGIFRYLPNKEP

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=292, Percent_Identity=32.8767123287671, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 36875; Mature: 36875

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLKIVCLMLLLLAHKVSAESSHIQIHGNTMGTTYSLTLDTADISLSELELQIAVEQEL
CCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCCHHHEEEEEEEHHHH
NKVNNGLSIFRAESEISKLNLNHGRQAIEISQQLWDVLAISKQVSQQTEGALDITLEPVI
HHHCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
EFWGFGVKARDLKGKNRGQLEYARSKTGMDGYVLDNGMIVKVIPDLAINPSAVAKGYGVD
HHHCCCCEEECCCCCCCCCEEEHHHCCCCCCEEECCCEEEEEECCCCCCHHHHHCCCCHH
RVANVLDDLGIANYLVEIGGELRAKGVAADGHFWNIAILRPEKFSMQIQEVVSLNNMAIA
HHHHHHHHHHHHHHHHHHCCCCEECEEEECCCEEEEEEECCHHHHHHHHHHHCCCCEEEE
TSGSYVNYLESGESQLSHIINPNTGMPVNNSVVSATVLHKQCAVADAFATALMVLDVERS
ECCCHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQIADSLGLAVMLIEQTDKGSVTHFSRGIFRYLPNKEP
HHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRKLKIVCLMLLLLAHKVSAESSHIQIHGNTMGTTYSLTLDTADISLSELELQIAVEQEL
CCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCCHHHEEEEEEEHHHH
NKVNNGLSIFRAESEISKLNLNHGRQAIEISQQLWDVLAISKQVSQQTEGALDITLEPVI
HHHCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
EFWGFGVKARDLKGKNRGQLEYARSKTGMDGYVLDNGMIVKVIPDLAINPSAVAKGYGVD
HHHCCCCEEECCCCCCCCCEEEHHHCCCCCCEEECCCEEEEEECCCCCCHHHHHCCCCHH
RVANVLDDLGIANYLVEIGGELRAKGVAADGHFWNIAILRPEKFSMQIQEVVSLNNMAIA
HHHHHHHHHHHHHHHHHHCCCCEECEEEECCCEEEEEEECCHHHHHHHHHHHCCCCEEEE
TSGSYVNYLESGESQLSHIINPNTGMPVNNSVVSATVLHKQCAVADAFATALMVLDVERS
ECCCHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQIADSLGLAVMLIEQTDKGSVTHFSRGIFRYLPNKEP
HHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]