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The map label for this gene is clpX [H]

Identifier: 167624685

GI number: 167624685

Start: 3358293

End: 3359570

Strand: Reverse

Name: clpX [H]

Synonym: Shal_2767

Alternate gene names: 167624685

Gene position: 3359570-3358293 (Counterclockwise)

Preceding gene: 167624686

Following gene: 167624684

Centisome position: 64.27

GC content: 43.9

Gene sequence:

>1278_bases
ATGGGTGAAGACAAAGGTAACGGTGACGGCGGAAAACTGCTGTACTGCTCTTTTTGTGGCAAGAGCCAGCATGAGGTAAG
AAAACTCATTGCAGGGCCTTCTGTATATGTTTGCGATGAGTGTGTTGAACTCTGCAATGACATCATTAGAGAAGAAATTA
AAGAGATTTCACCAAAGCAAGATCAAGACAAGTTGCCGACCCCTCATGAGCTAAGAGCTCATTTGGATGATTATGTAATT
GGTCAAGATAAAGCTAAAAAAGTACTTGCTGTTGCAGTGTATAACCACTACAAGCGCCTTAGAAATGCTACCCCTAAAGA
TGGCGTAGAACTGGGTAAGAGTAACATCTTGCTAATTGGCCCAACGGGTAGTGGTAAAACCTTACTAGCAGAAACACTTG
CACGTGTCCTTGACGTGCCATTTACGATGGCCGATGCAACCACGCTAACTGAGGCGGGTTACGTAGGTGAAGATGTTGAG
AACATCATTCAAAAGCTACTGCAAAAGTGCGACTACGATGTAGAAAAAGCCCAGCGCGGTATCGTGTATATCGATGAGAT
TGATAAAATCAGTCGTAAGTCTGATAATCCATCGATTACTCGTGACGTATCGGGTGAGGGTGTGCAGCAAGCACTGCTTA
AGCTAATTGAAGGCACTATTGCAGCTGTACCGCCACAAGGTGGTCGTAAGCACCCACAGCAAGAGTTCTTACAAGTCGAT
ACTTCTAAGATCTTGTTCATCTGTGGTGGTGCATTCGCAGGCCTTGAAAAGGTCATTGAGCAGCGTGCTCATGTTGGTAC
CGGTATTGGTTTTGGTGCTGAAGTAAAAGGTGAAGCAGATAAGAAGTCTATCTCTGATACGCTTTTACAAGTTGAGCCTG
AAGATTTAGTTAAGTTCGGTCTTATTCCTGAATTTATCGGTCGTCTGCCTGTACTTGCGACACTGTCAGAGCTTGACGAT
GAAGCCTTGATTCAAATTCTGTCTGAGCCAAAAAATGCGATTACTAAACAGTTTGCCGCATTATTTGAGATGGAAAATGT
AGAGCTTGAGTTTAGAGACGATGCATTAAAGGCGATTGCTCTTAAAGCACAAACTCGTAAGACGGGGGCTCGTGGTCTTC
GTTCTATTGTTGAAGGGATCCTACTTGATATCATGTATGATCTGCCATCGACAGATGATGTCGCTAAAGTGGTTATCGAT
GAGTCTGTGGTTAAAGGTGAGTCAAGTCCTATCTTGATCTACGCTAATAGCGAAGCACAAACCGCATCGGCAGAATAA

Upstream 100 bases:

>100_bases
AGCAAAACGAAGCTGATTTTTACTTCGCTCTGAGCTATGCTCAAATAAGAAGTAACGAAAAGATTTAGGCAGTGAAAATA
CTGCAAATAGAGGTAAAGTA

Downstream 100 bases:

>100_bases
AATCTCGTCTACACTCATGAGTGAATTATAAAGGAGCCTATTTGGCTCCTTTTTTGTACACTTATTTAATTAATTGTTTT
TCGGCATTGAATCCTATCTA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVI
GQDKAKKVLAVAVYNHYKRLRNATPKDGVELGKSNILLIGPTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
TSKILFICGGAFAGLEKVIEQRAHVGTGIGFGAEVKGEADKKSISDTLLQVEPEDLVKFGLIPEFIGRLPVLATLSELDD
EALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVID
ESVVKGESSPILIYANSEAQTASAE

Sequences:

>Translated_425_residues
MGEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVI
GQDKAKKVLAVAVYNHYKRLRNATPKDGVELGKSNILLIGPTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
TSKILFICGGAFAGLEKVIEQRAHVGTGIGFGAEVKGEADKKSISDTLLQVEPEDLVKFGLIPEFIGRLPVLATLSELDD
EALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVID
ESVVKGESSPILIYANSEAQTASAE
>Mature_424_residues
GEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVIG
QDKAKKVLAVAVYNHYKRLRNATPKDGVELGKSNILLIGPTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLEKVIEQRAHVGTGIGFGAEVKGEADKKSISDTLLQVEPEDLVKFGLIPEFIGRLPVLATLSELDDE
ALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVIDE
SVVKGESSPILIYANSEAQTASAE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=335, Percent_Identity=51.6417910447761, Blast_Score=308, Evalue=8e-84,
Organism=Escherichia coli, GI1786642, Length=422, Percent_Identity=81.5165876777251, Blast_Score=707, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=107, Percent_Identity=42.9906542056075, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=327, Percent_Identity=44.0366972477064, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71982905, Length=327, Percent_Identity=44.0366972477064, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=38.8324873096447, Blast_Score=247, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=41.2955465587045, Blast_Score=176, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=424, Percent_Identity=39.8584905660377, Blast_Score=267, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24648291, Length=317, Percent_Identity=47.3186119873817, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24648289, Length=317, Percent_Identity=47.3186119873817, Blast_Score=284, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46303; Mature: 46172

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQ
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DQDKLPTPHELRAHLDDYVIGQDKAKKVLAVAVYNHYKRLRNATPKDGVELGKSNILLIG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEE
PTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRG
CCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
EEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHC
TSKILFICGGAFAGLEKVIEQRAHVGTGIGFGAEVKGEADKKSISDTLLQVEPEDLVKFG
CCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHC
LIPEFIGRLPVLATLSELDDEALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIA
CHHHHHCCCHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHH
LKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVIDESVVKGESSPILIYANSEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
TASAE
CCCCC
>Mature Secondary Structure 
GEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQ
CCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DQDKLPTPHELRAHLDDYVIGQDKAKKVLAVAVYNHYKRLRNATPKDGVELGKSNILLIG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEE
PTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRG
CCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
EEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHC
TSKILFICGGAFAGLEKVIEQRAHVGTGIGFGAEVKGEADKKSISDTLLQVEPEDLVKFG
CCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHC
LIPEFIGRLPVLATLSELDDEALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIA
CHHHHHCCCHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHH
LKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVIDESVVKGESSPILIYANSEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
TASAE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA