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The map label for this gene is melR [H]

Identifier: 167624555

GI number: 167624555

Start: 3194757

End: 3195635

Strand: Reverse

Name: melR [H]

Synonym: Shal_2635

Alternate gene names: 167624555

Gene position: 3195635-3194757 (Counterclockwise)

Preceding gene: 167624556

Following gene: 167624554

Centisome position: 61.14

GC content: 44.71

Gene sequence:

>879_bases
ATGTTTGATTGGGTCGAAAAAATTGCCTTTAACGAGGCCAGTCCATTAACGGTGCAGGCTCAAGATACACAGTTTGGCTT
TCATCGTAAAAAGCCTGCGGTGATGGAGCACAGTCATTGGCATGGTCATATTGAAATTAATTACCTGTTTGATTGCTCAG
CCGACTATCTGATTAATGGCCAAGAGATCACCGTGCCCGAGGGGCGAATGATCATCTTCTGGGCATCGTTTCCCCATCAA
ATGACCGCCTCTCGTGGCAATGGTGAACTGGTCAATATCTATATCCCCTTGCCGTCTTTTCTGACCTGGATGCTACCAAG
TGGCTTTGTTAGCCAGTTACTACATGGTGAGGTTATTGTCTCAGACAGTCTTTACGCCTGTGATAAGCAGCTGACTCAGA
TCTGGGAAACCGATATTAAGGGTAATGAACCGCTTTTGACTAGCCAAGTGATTAACGAGATCCGCGGCCGTATTCGTCGC
ATGTCGATAGAGCAGTACAGCACCTATGAATTAGCCAATAAAGTGGTTAAGCGCGAGGACAAACCTGTGTTTGGTGGCTT
AAACCATATTCAAACCATGCTGCGTTATATTGCCGATAATTACGATCAGAAAATTACAATTGAAAATGTTTCAAGCTCAA
CCGGCCTGCATAAAAACTATGCCATGAAGCTATTTAATCGGGTGATGAAGGTGTCGATTAAGCAATACATCAACCAACTT
AGGCTGCAACATGCCCAGGCATTATTGATTGATACCCAAAGCCCTGTGCTCAATATTGCCCTTGAAGCCGGCTTTGGTTC
CGTGAGTCGCTTTTACGATATTTTTCAGCGTGAATTTGCCATGTCACCTTTGGAGTTTCGTCGTAAGGTGAATGGCTAA

Upstream 100 bases:

>100_bases
TAAGCAATGGATTAGCTTGGCAATGAATTGGTGGCCAATGGCTTGGTTTGAAATAAGCAGACTATCAATAGCAAACGGGT
GAATAATAGGGATTAGGCTG

Downstream 100 bases:

>100_bases
TACTAAGCCTGATATTCTAACGTTCTGCTCATTCAGATTAGTTAAGGTGATTTTTTAGGAAGGCTTTACGACTTTCTAGT
AAGCGAACTCATGATTGTTC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFDWVEKIAFNEASPLTVQAQDTQFGFHRKKPAVMEHSHWHGHIEINYLFDCSADYLINGQEITVPEGRMIIFWASFPHQ
MTASRGNGELVNIYIPLPSFLTWMLPSGFVSQLLHGEVIVSDSLYACDKQLTQIWETDIKGNEPLLTSQVINEIRGRIRR
MSIEQYSTYELANKVVKREDKPVFGGLNHIQTMLRYIADNYDQKITIENVSSSTGLHKNYAMKLFNRVMKVSIKQYINQL
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFAMSPLEFRRKVNG

Sequences:

>Translated_292_residues
MFDWVEKIAFNEASPLTVQAQDTQFGFHRKKPAVMEHSHWHGHIEINYLFDCSADYLINGQEITVPEGRMIIFWASFPHQ
MTASRGNGELVNIYIPLPSFLTWMLPSGFVSQLLHGEVIVSDSLYACDKQLTQIWETDIKGNEPLLTSQVINEIRGRIRR
MSIEQYSTYELANKVVKREDKPVFGGLNHIQTMLRYIADNYDQKITIENVSSSTGLHKNYAMKLFNRVMKVSIKQYINQL
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFAMSPLEFRRKVNG
>Mature_292_residues
MFDWVEKIAFNEASPLTVQAQDTQFGFHRKKPAVMEHSHWHGHIEINYLFDCSADYLINGQEITVPEGRMIIFWASFPHQ
MTASRGNGELVNIYIPLPSFLTWMLPSGFVSQLLHGEVIVSDSLYACDKQLTQIWETDIKGNEPLLTSQVINEIRGRIRR
MSIEQYSTYELANKVVKREDKPVFGGLNHIQTMLRYIADNYDQKITIENVSSSTGLHKNYAMKLFNRVMKVSIKQYINQL
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFAMSPLEFRRKVNG

Specific function: Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790559, Length=276, Percent_Identity=34.0579710144928, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008917
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33667; Mature: 33667

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDWVEKIAFNEASPLTVQAQDTQFGFHRKKPAVMEHSHWHGHIEINYLFDCSADYLING
CCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHCCCCCEEEEEEEEEEECCCCEEECC
QEITVPEGRMIIFWASFPHQMTASRGNGELVNIYIPLPSFLTWMLPSGFVSQLLHGEVIV
CEEECCCCCEEEEEECCCCHHHCCCCCCCEEEEEECHHHHHHHHCCHHHHHHHHCCCEEE
SDSLYACDKQLTQIWETDIKGNEPLLTSQVINEIRGRIRRMSIEQYSTYELANKVVKRED
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KPVFGGLNHIQTMLRYIADNYDQKITIENVSSSTGLHKNYAMKLFNRVMKVSIKQYINQL
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFAMSPLEFRRKVNG
HHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MFDWVEKIAFNEASPLTVQAQDTQFGFHRKKPAVMEHSHWHGHIEINYLFDCSADYLING
CCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHCCCCCEEEEEEEEEEECCCCEEECC
QEITVPEGRMIIFWASFPHQMTASRGNGELVNIYIPLPSFLTWMLPSGFVSQLLHGEVIV
CEEECCCCCEEEEEECCCCHHHCCCCCCCEEEEEECHHHHHHHHCCHHHHHHHHCCCEEE
SDSLYACDKQLTQIWETDIKGNEPLLTSQVINEIRGRIRRMSIEQYSTYELANKVVKRED
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KPVFGGLNHIQTMLRYIADNYDQKITIENVSSSTGLHKNYAMKLFNRVMKVSIKQYINQL
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFAMSPLEFRRKVNG
HHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]