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The map label for this gene is xapR [H]

Identifier: 167624464

GI number: 167624464

Start: 3072690

End: 3073667

Strand: Reverse

Name: xapR [H]

Synonym: Shal_2542

Alternate gene names: 167624464

Gene position: 3073667-3072690 (Counterclockwise)

Preceding gene: 167624468

Following gene: 167624462

Centisome position: 58.8

GC content: 44.48

Gene sequence:

>978_bases
ATGGATACTAAATTTGTGAACAATGACCATAGCGTTGCACCGCTAGATTTAAATAGCCTCTATTGGGCTGAGCGTATTAG
TATGAAAATGCTGCGGTATTTTTATGTGGCAAGTCATAGTCAAACTTTAACTCAGGCTGCTGAGCGGCTACATATTTCCA
AGTCTCCCTTGAGCGCAAAGATGAGAGAGCTTGAAACGATTCTTGGCGTCAAGCTATTTAATCGGGATAAAAGAAGTGTT
CAGCTGACTTCCACTGGCTTGATGTTACGCCATGAGTGCCAGTCAATTTTTAGTGTAATGGAAGGTGCGGTGAGTAAAGT
GACTCAGCACGCTAGAGAAACCCAGGGGCAGCTTCGTTTAGGTATTGTTAGTTCGATATTTTGGGCGGGGTTTGGTTATG
CCTGTCAGCAGTTGAAAGCCCAATATCCAAGTATTCAATTTGAGTTCTTGGAGCTATCGCCACAGCAGCAGAAGGTGGCA
CTGTTTAATAATGAGATCGATATAGGCTTTGTTCGTTACGCCGACACTTTAGATATTACCCCGTTAGAGTCCTGCAATCT
TTACTGCGAGCCTATGGTGATCGCGCTTTGTGACCGGCATGAACTCAGTGGACGGTCTCAGTTATGTTTGTCGGAACTGG
CCAATGAAAAGTTTGTCATCATGAGTCATAAAAACTCGGCTTCGGCACAGTTGGTCGTCAATCATTGCATCAAGGAGGGC
TTTATCCCACAAATCACTCAAGAGGTGGTGGAGCCGATGACTTTGATGAACGTGATAGAGAGTCAGGCTGGGATCTCTGT
CGTTCCCCAAAGCTTTAGTCGTCAGAGTTGGAGACATATTCGCTTTATATCGCTAAGGCAAGAGATCCACGCCAATATTT
GCGCCGTGTATAACCCACAAAAAATCAACCCAGAGAAACAGGCTCTGATCCAGTCATTGCATCAGTTTATGAATGCAGAA
TCATTAAAGCCTATTTAG

Upstream 100 bases:

>100_bases
GCGGATTGAACGCTTTGAGTGGTAAAACTGTTATTTAAGATATTGAAAACTGCTTCAACGTTCAGTTTTTACACCGGAAT
AGCCCAGTTATGGCAAAGAA

Downstream 100 bases:

>100_bases
TCTTTACCCTGATAGGTATAACAATGCAGATAGAAGAAGCCCGCTCTCACAAGAGCGGTTTTTTTGATAGCGAAAAGCTA
TTGGTTTTCGATTCGTTTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MDTKFVNNDHSVAPLDLNSLYWAERISMKMLRYFYVASHSQTLTQAAERLHISKSPLSAKMRELETILGVKLFNRDKRSV
QLTSTGLMLRHECQSIFSVMEGAVSKVTQHARETQGQLRLGIVSSIFWAGFGYACQQLKAQYPSIQFEFLELSPQQQKVA
LFNNEIDIGFVRYADTLDITPLESCNLYCEPMVIALCDRHELSGRSQLCLSELANEKFVIMSHKNSASAQLVVNHCIKEG
FIPQITQEVVEPMTLMNVIESQAGISVVPQSFSRQSWRHIRFISLRQEIHANICAVYNPQKINPEKQALIQSLHQFMNAE
SLKPI

Sequences:

>Translated_325_residues
MDTKFVNNDHSVAPLDLNSLYWAERISMKMLRYFYVASHSQTLTQAAERLHISKSPLSAKMRELETILGVKLFNRDKRSV
QLTSTGLMLRHECQSIFSVMEGAVSKVTQHARETQGQLRLGIVSSIFWAGFGYACQQLKAQYPSIQFEFLELSPQQQKVA
LFNNEIDIGFVRYADTLDITPLESCNLYCEPMVIALCDRHELSGRSQLCLSELANEKFVIMSHKNSASAQLVVNHCIKEG
FIPQITQEVVEPMTLMNVIESQAGISVVPQSFSRQSWRHIRFISLRQEIHANICAVYNPQKINPEKQALIQSLHQFMNAE
SLKPI
>Mature_325_residues
MDTKFVNNDHSVAPLDLNSLYWAERISMKMLRYFYVASHSQTLTQAAERLHISKSPLSAKMRELETILGVKLFNRDKRSV
QLTSTGLMLRHECQSIFSVMEGAVSKVTQHARETQGQLRLGIVSSIFWAGFGYACQQLKAQYPSIQFEFLELSPQQQKVA
LFNNEIDIGFVRYADTLDITPLESCNLYCEPMVIALCDRHELSGRSQLCLSELANEKFVIMSHKNSASAQLVVNHCIKEG
FIPQITQEVVEPMTLMNVIESQAGISVVPQSFSRQSWRHIRFISLRQEIHANICAVYNPQKINPEKQALIQSLHQFMNAE
SLKPI

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=291, Percent_Identity=30.2405498281787, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787879, Length=265, Percent_Identity=28.3018867924528, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=26.7206477732794, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788887, Length=251, Percent_Identity=28.2868525896414, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=21.0714285714286, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=25.7028112449799, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=242, Percent_Identity=23.5537190082645, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36981; Mature: 36981

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKFVNNDHSVAPLDLNSLYWAERISMKMLRYFYVASHSQTLTQAAERLHISKSPLSAK
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHH
MRELETILGVKLFNRDKRSVQLTSTGLMLRHECQSIFSVMEGAVSKVTQHARETQGQLRL
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GIVSSIFWAGFGYACQQLKAQYPSIQFEFLELSPQQQKVALFNNEIDIGFVRYADTLDIT
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHEECCCCCEEEEEEECCCCCC
PLESCNLYCEPMVIALCDRHELSGRSQLCLSELANEKFVIMSHKNSASAQLVVNHCIKEG
CCCCCCCEECHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCC
FIPQITQEVVEPMTLMNVIESQAGISVVPQSFSRQSWRHIRFISLRQEIHANICAVYNPQ
CCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
KINPEKQALIQSLHQFMNAESLKPI
CCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDTKFVNNDHSVAPLDLNSLYWAERISMKMLRYFYVASHSQTLTQAAERLHISKSPLSAK
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHH
MRELETILGVKLFNRDKRSVQLTSTGLMLRHECQSIFSVMEGAVSKVTQHARETQGQLRL
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GIVSSIFWAGFGYACQQLKAQYPSIQFEFLELSPQQQKVALFNNEIDIGFVRYADTLDIT
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHEECCCCCEEEEEEECCCCCC
PLESCNLYCEPMVIALCDRHELSGRSQLCLSELANEKFVIMSHKNSASAQLVVNHCIKEG
CCCCCCCEECHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCC
FIPQITQEVVEPMTLMNVIESQAGISVVPQSFSRQSWRHIRFISLRQEIHANICAVYNPQ
CCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
KINPEKQALIQSLHQFMNAESLKPI
CCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]