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The map label for this gene is zraR [H]

Identifier: 167624441

GI number: 167624441

Start: 3039240

End: 3040592

Strand: Reverse

Name: zraR [H]

Synonym: Shal_2519

Alternate gene names: 167624441

Gene position: 3040592-3039240 (Counterclockwise)

Preceding gene: 167624442

Following gene: 167624439

Centisome position: 58.17

GC content: 49.15

Gene sequence:

>1353_bases
ATGAGTCATGCCCCCCTACAGATCTTAGTCGTTGAAGATGAACCGGATCAACGCGAGCTTATCTGCCAAATTTTAGCTGC
AAATGAATATCAGATCCGCAGCGCTGCAAGCGTTGAAGAAGCCATACTATCGATAAAACAGAGTGTGCCAGACCTCGTGT
TTTCAGACTGGAAGCTTGGACAATTGACTGGTATGGATCTGCTGAGCTACGTGAGACGAGAGTACCCCGACCTTGGCTTT
ATTATCGCCACGGCTTACGGCACTATCACCCACGCGGTAGATGCCATGCAAGCGGGGGCTGATGATTATCTGTCAAAGCC
ATATCAGCGCCAATCACTGTTGATGGCGATAGACAAAGTCGCTAAGTCGTTGACACTTAAACAGCAAAATCGACGCTTAG
CCTCAGAGTTATCCCAGCAACAAGAGCTGGTGGGCTTAGTGGGTAAGGCGCCCTGTATGCAAAAGGTGTACGCCCGTGTG
CAACGGGTGAGTGCAACCGACGCCACTGTGCTGATTGGCGGCGAAAGTGGTACGGGTAAGGAGCTTGCGGCTCGGGCCTT
GTACCAACTGTCGAGCCGACAGCATAAGCCGTTTGTCGCTATCAACTGTGGCGCCATTCCTGAAACCCTTGCCGAATCAG
AGCTTTTTGGCGCAGAGAAGGGGGCGTTTACCGGTGCGAATACCTTAAAGATAGGTAAGCTTGAAGCCGCTAATGGGGGC
ACCATATTTCTTGATGAGATAGGGGAGCTGCCTCTGCTGCAACAAACTAAGCTATTGCGATTTTTACAAGAAGGAGTGAT
CTCACGGCTTGGACAAAATGGTGAGATAAAGTTAGATGTTAGGGTCATCGCAGCGACTCACCGAAATCTTAAAGAGGAGG
TGGAGCTGGGTAACTTCAGAGAAGATCTGTTTTATCGATTGAACGTGGTTCCCATTGATATGCCGCCACTTAGAGCACGT
CGAGAAGACATTGGCCGACTGATTGAACATTTTCTCAAAATCCACGGTGGTCAGTACGGGGTTGAAGTCGTTAAGCTAAG
CGCTGACACCATGAAATCACTGCTGGATTATCCTTGGCCTGGTAATGTACGCGAGCTGTCGAATCGAATTGAGCGATTTG
TGCTACTCGGTGATGAACAAGAGCTGGTTGCCGAATTACAATCTGGCAAAAGTACAATTAACCCCAATCATTTTGTGCTA
CCCGTTGATGGTTTTGAGTGGGAAGCATTTGAGAAAGATTGCTTACAGCAGGCGATGGCACGTCATGACCGCAATCGAAC
CCAAGCGGCAAAGCAACTGGGTTTAAGCTACAAGGCCTTCTTGTACCGCCTAGAGAAACATCAACTGGTGTAA

Upstream 100 bases:

>100_bases
TTGCAGATAATCCCCAAGGAGGCACAATCGTGACACTCATTTTTGGTCTTGGTACGCAACAGCTTGAACAACAAGCCGAT
ATAGAACAAGGAGGTCACTC

Downstream 100 bases:

>100_bases
CCCGTTACTGATACTTGAACGCTAATAGGAATAGCGATGAGCACTCGCTATTCGCATTAGCGACTATTGTGACGCCACGA
GCCCGGAGATAATTATCAGT

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSHAPLQILVVEDEPDQRELICQILAANEYQIRSAASVEEAILSIKQSVPDLVFSDWKLGQLTGMDLLSYVRREYPDLGF
IIATAYGTITHAVDAMQAGADDYLSKPYQRQSLLMAIDKVAKSLTLKQQNRRLASELSQQQELVGLVGKAPCMQKVYARV
QRVSATDATVLIGGESGTGKELAARALYQLSSRQHKPFVAINCGAIPETLAESELFGAEKGAFTGANTLKIGKLEAANGG
TIFLDEIGELPLLQQTKLLRFLQEGVISRLGQNGEIKLDVRVIAATHRNLKEEVELGNFREDLFYRLNVVPIDMPPLRAR
REDIGRLIEHFLKIHGGQYGVEVVKLSADTMKSLLDYPWPGNVRELSNRIERFVLLGDEQELVAELQSGKSTINPNHFVL
PVDGFEWEAFEKDCLQQAMARHDRNRTQAAKQLGLSYKAFLYRLEKHQLV

Sequences:

>Translated_450_residues
MSHAPLQILVVEDEPDQRELICQILAANEYQIRSAASVEEAILSIKQSVPDLVFSDWKLGQLTGMDLLSYVRREYPDLGF
IIATAYGTITHAVDAMQAGADDYLSKPYQRQSLLMAIDKVAKSLTLKQQNRRLASELSQQQELVGLVGKAPCMQKVYARV
QRVSATDATVLIGGESGTGKELAARALYQLSSRQHKPFVAINCGAIPETLAESELFGAEKGAFTGANTLKIGKLEAANGG
TIFLDEIGELPLLQQTKLLRFLQEGVISRLGQNGEIKLDVRVIAATHRNLKEEVELGNFREDLFYRLNVVPIDMPPLRAR
REDIGRLIEHFLKIHGGQYGVEVVKLSADTMKSLLDYPWPGNVRELSNRIERFVLLGDEQELVAELQSGKSTINPNHFVL
PVDGFEWEAFEKDCLQQAMARHDRNRTQAAKQLGLSYKAFLYRLEKHQLV
>Mature_449_residues
SHAPLQILVVEDEPDQRELICQILAANEYQIRSAASVEEAILSIKQSVPDLVFSDWKLGQLTGMDLLSYVRREYPDLGFI
IATAYGTITHAVDAMQAGADDYLSKPYQRQSLLMAIDKVAKSLTLKQQNRRLASELSQQQELVGLVGKAPCMQKVYARVQ
RVSATDATVLIGGESGTGKELAARALYQLSSRQHKPFVAINCGAIPETLAESELFGAEKGAFTGANTLKIGKLEAANGGT
IFLDEIGELPLLQQTKLLRFLQEGVISRLGQNGEIKLDVRVIAATHRNLKEEVELGNFREDLFYRLNVVPIDMPPLRARR
EDIGRLIEHFLKIHGGQYGVEVVKLSADTMKSLLDYPWPGNVRELSNRIERFVLLGDEQELVAELQSGKSTINPNHFVLP
VDGFEWEAFEKDCLQQAMARHDRNRTQAAKQLGLSYKAFLYRLEKHQLV

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=452, Percent_Identity=39.6017699115044, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1788550, Length=449, Percent_Identity=38.3073496659243, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1790299, Length=376, Percent_Identity=42.2872340425532, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1788905, Length=453, Percent_Identity=39.514348785872, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1789233, Length=356, Percent_Identity=39.0449438202247, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87082117, Length=272, Percent_Identity=48.1617647058824, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082152, Length=323, Percent_Identity=43.6532507739938, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789087, Length=257, Percent_Identity=47.8599221789883, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1786524, Length=362, Percent_Identity=39.5027624309392, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787583, Length=311, Percent_Identity=40.1929260450161, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=36.9565217391304, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789828, Length=258, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081858, Length=209, Percent_Identity=34.9282296650718, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=32.2314049586777, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50255; Mature: 50124

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAPLQILVVEDEPDQRELICQILAANEYQIRSAASVEEAILSIKQSVPDLVFSDWKLG
CCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCC
QLTGMDLLSYVRREYPDLGFIIATAYGTITHAVDAMQAGADDYLSKPYQRQSLLMAIDKV
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
AKSLTLKQQNRRLASELSQQQELVGLVGKAPCMQKVYARVQRVSATDATVLIGGESGTGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
ELAARALYQLSSRQHKPFVAINCGAIPETLAESELFGAEKGAFTGANTLKIGKLEAANGG
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCC
TIFLDEIGELPLLQQTKLLRFLQEGVISRLGQNGEIKLDVRVIAATHRNLKEEVELGNFR
EEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHCCCHH
EDLFYRLNVVPIDMPPLRARREDIGRLIEHFLKIHGGQYGVEVVKLSADTMKSLLDYPWP
HHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCC
GNVRELSNRIERFVLLGDEQELVAELQSGKSTINPNHFVLPVDGFEWEAFEKDCLQQAMA
CCHHHHHHHHHHEEEECCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
RHDRNRTQAAKQLGLSYKAFLYRLEKHQLV
HHCCHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SHAPLQILVVEDEPDQRELICQILAANEYQIRSAASVEEAILSIKQSVPDLVFSDWKLG
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCC
QLTGMDLLSYVRREYPDLGFIIATAYGTITHAVDAMQAGADDYLSKPYQRQSLLMAIDKV
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
AKSLTLKQQNRRLASELSQQQELVGLVGKAPCMQKVYARVQRVSATDATVLIGGESGTGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
ELAARALYQLSSRQHKPFVAINCGAIPETLAESELFGAEKGAFTGANTLKIGKLEAANGG
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCC
TIFLDEIGELPLLQQTKLLRFLQEGVISRLGQNGEIKLDVRVIAATHRNLKEEVELGNFR
EEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHCCCHH
EDLFYRLNVVPIDMPPLRARREDIGRLIEHFLKIHGGQYGVEVVKLSADTMKSLLDYPWP
HHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCC
GNVRELSNRIERFVLLGDEQELVAELQSGKSTINPNHFVLPVDGFEWEAFEKDCLQQAMA
CCHHHHHHHHHHEEEECCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
RHDRNRTQAAKQLGLSYKAFLYRLEKHQLV
HHCCHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]